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Docteur de l'université Automatic Segmentation and Shape Analysis ...

Docteur de l'université Automatic Segmentation and Shape Analysis ...

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Chapter 4 Statistical shape mo<strong>de</strong>l of Hippocampus 89<br />

Algorithm 9 Groupwise optimization with fluid regularization. Adapted <strong>and</strong><br />

modified from Davies et al. (2008b).<br />

1: Initialize with ui ← 0, vi ← 0, i = 1, · · · , n.<br />

2: while u not converging do<br />

3: for all shapes images Si, i = 1, · · · , n do<br />

4: Compute Fi given ui (eq. 4.37)<br />

5: Compute vi given Fi (eq. 4.41, Cahill et al., 2007)<br />

6: Update ui: ← ui + τ(vi − (vi · ∇)ui) (eq. 4.45)<br />

7: end for<br />

8: if the minimum Jacobian of any ui is below threshold then<br />

9: for all shapes images Si, i = 1, · · · , n do<br />

10: Si(x) ← Si(x − ui) (eq. 4.46)<br />

11: ui ← 0, vi ← 0<br />

12: end for<br />

13: end if<br />

14: if reorientation required then<br />

15: for all shapes images Si, i = 1, · · · , n do<br />

16: Si(x) ← Si(x − ui) (eq. 4.46)<br />

17: reorient the octahedron unfolding gi<br />

18: update Si<br />

19: ui ← 0, vi ← 0<br />

20: end for<br />

21: end if<br />

22: end while<br />

where<br />

(x s i , y s i , z s i ) T = fi ◦ γi(θs, φs) = Si ◦ ψi(ıs, js), s = 1, 2, · · · , k (4.48)<br />

are the sampled points. For sampling on subdivi<strong>de</strong>d octahedron k = 4N 2 +2. The<br />

mean<br />

gives the data matrix<br />

¯X = 1<br />

n<br />

n∑<br />

Xi, (4.49)<br />

i=1<br />

X = (X1 − ¯ X, X2 − ¯ X, · · · , Xn − ¯ X). (4.50)<br />

A PCA is performed such that each shape can be approximated by a subspace<br />

spanned by the eigenvectors of the larger covariance matrix<br />

X = ¯ X + Wb, (4.51)

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