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Docteur de l'université Automatic Segmentation and Shape Analysis ...

Docteur de l'université Automatic Segmentation and Shape Analysis ...

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84 Chapter 4 Statistical shape mo<strong>de</strong>l of Hippocampus<br />

position in the l<strong>and</strong>mark Si(x) has been <strong>de</strong>rived by Ericsson <strong>and</strong> Åström (2003)<br />

based on the SVD <strong>de</strong>composition of the data matrix, <strong>and</strong> by Hladůvka <strong>and</strong> Bühler<br />

(2005) on the eigen-<strong>de</strong>composition of the covariance matrix Σ.<br />

The variation based on eigen-<strong>de</strong>composition is used in the implementation. The<br />

variation of the cost function with respect to the displacement ui at pixel (ı, j) in<br />

i-th shape image can be calculated by applying the chain rule<br />

δLMDL<br />

δui(xıj)<br />

∂LMDL ∂λm<br />

= · ·<br />

∂λm ∂Σjl<br />

δΣjl<br />

δSi(xıj)<br />

δSi(xıj)<br />

· , (4.31)<br />

δui(xıj)<br />

where Einstein summation convention applies to the repeated subscripts m, j, l.<br />

The partial <strong>de</strong>rivative of the cost function with respect to the eigenvalues is<br />

∂LMDL<br />

=<br />

∂λm ⎧<br />

⎪⎨ 1<br />

λm<br />

⎪⎩<br />

1<br />

λc<br />

if λm ≥ λc,<br />

if λm < λc.<br />

(4.32)<br />

The partial <strong>de</strong>rivative of the eigenvalue with respect to the element of covariance<br />

matrix Σjl is calculated from the eigen-<strong>de</strong>composition<br />

Σ = WΛW T , (4.33)<br />

where Λ is the diagonal matrix of eigenvalues, <strong>and</strong> W is the matrix of eigenvectors,<br />

which gives the <strong>de</strong>rivative<br />

∂λ m<br />

∂Σjl<br />

= WjmWlm, (4.34)<br />

where Wlm, Wjm are elements of W. The variation of the covariance matrix with<br />

respect to the position of the point Si(xıj) is <strong>de</strong>rived from (4.29)<br />

δΣjl<br />

δSi(xıj) =<br />

1<br />

(2N + 1) 2<br />

[(<br />

δij − 1<br />

) (<br />

Sl(xıj) + δil −<br />

n<br />

1<br />

) ]<br />

Sj(xıj) ∈ R<br />

n<br />

1×3 . (4.35)<br />

The variation of the point Si(xıj) with respect to the displacement u<br />

[ ]<br />

δSi(xıj)<br />

δui(xıj)<br />

∈ R 3×2<br />

(4.36)

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