The Basics of MRI: T1 vs. T2
The Basics of MRI: T1 vs. T2
The Basics of MRI: T1 vs. T2
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Frank Minja, HMS III<br />
Gillian Lieberman, MD<br />
<strong>The</strong> Fifth Element<br />
• MR contrast agents<br />
• Gadolinium (Gd) is a paramagnetic metal ion that causes<br />
fluctuating magnetic fields around protons.<br />
• Gd alters <strong>T1</strong> and <strong>T2</strong> values <strong>of</strong> tissues.<br />
• Tissues that are vascular will have a brighter signal<br />
compared to non-vascular tissues.<br />
• Difference in signal = MR contrast!!<br />
• Gd is typically chelated to lessen its toxicity.<br />
• MR contrast agents are very safe to use in patients with<br />
renal insufficiency or allergies to CT contrast<br />
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