BIOBAR : USER MANUAL
BIOBAR : USER MANUAL
BIOBAR : USER MANUAL
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o Returns the best result<br />
REPLACE<br />
o Highlights the motif in each sequence<br />
o Dyad Motif Search<br />
The Dyad Motif Search can only be completed for DNA sequences. An<br />
error message will be displayed if a protein or RNA sequence is selected.<br />
If sequences of all types are selected, the motif search will only be<br />
completed for the DNA sequence(s).<br />
o Consensus Logo<br />
The consensus logo can only be generated with a motif of DNA sequences<br />
The motif to generate a pseudo-consensus logo can be selected in the<br />
document or entered into a pop-up input box when the button is clicked.<br />
Information Content will be calculated using R sequence or Relative<br />
Entropy, depending on which is selected in the Advanced Options<br />
The text is likely to be small, and can be scaled up or down using the<br />
arrows in the Resources Group (though resolution may be lost)<br />
Pair-Wise Alignment<br />
o Needleman-Wuncsh and Smith-Watermann<br />
Pair-wise alignment can be performed with both DNA and Protein<br />
sequences.<br />
Protein sequences are scored using the BLOSUM62 matrix and DNA<br />
sequences are scored using user-defined values.
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