Jennifer Kehlet Barton, Ph.D. - Department of Biomedical ...

Curriculum Vitae Jennifer Kehlet Barton
Jennifer Kehlet Barton, Ph.D.
The University of Arizona: Home:
1657 E Helen St. 6939 N Pusch Peak Pl
Tucson, AZ 85721-0240 Tucson, AZ 85718
p: 520-621-4116 f: 520-621-8076 c: 520-360-5088
Education:
1988 B.S., Electrical Engineering, The University of Texas at Austin
1993 M.S., Electrical Engineering, The University of California, Irvine
1998 Ph.D., Biomedical Engineering, The University of Texas at Austin
Positions:
1988-1994 McDonnell Douglas Aerospace (now Boeing Corp.), Huntington Beach, CA. Engineer/Scientist
Specialist, International Space Station
1994-1998 The University of Texas, Austin, TX. Research Assistant, Biomedical Engineering Program
1998-pres. The University of Arizona, Tucson, AZ. Assistant Professor (1998-2003), Associate Professor
(2003-2009), Professor (2009-pres.) Biomedical Engineering (primary appointment), Electrical
and Computer Engineering Department, College of Optical Sciences, Agriculture and Biosystems
Engineering Department, Arizona Cancer Center, Bio5 Institute
2006 Visiting Scientist, Beckman Laser Institute, The University of California, Irvine
2007-2009 Director, Division of Biomedical Engineering, The University of Arizona
2007-pres. Chair, Biomedical Engineering Graduate Interdisciplinary Program, The University of Arizona
2009-pres. Head, Department of Biomedical Engineering, The University of Arizona
2009-pres. Assistant Director, BIO5 Institute
Professional Activities:
2003-2007 National Institutes of Health Biomedical Imaging Technology (BMIT, formerly DMG) Study Section
Charter Member (3 review sessions per year)
Various: Proposal reviewer for: National Science Foundation, National Institutes of Health ad hoc and site
visit committees, California Breast Cancer Research Program, California Tobacco-Related
Disease Research Program, Philip Morris External Research Program, The University of Arizona
Small Grants Program, Center for Integration of Medicine and Innovative Technology, Technology
Foundation STW (Dutch Foundation), Connecticut Innovations, Science and Technology Center
Ukraine
Various: Journal Reviewer for: Annals of Biomedical Engineering, Applied Optics, Dermatological Surgery,
Expert Reviews in Dermatology, IEEE Transactions on Biomedical Engineering, IEEE
Transactions on Education, IEEE Transactions on Medical Imaging, Journal of Biomedical Optics,
Journal of Lightwave Technology, Journal of the Optical Society of America, Lasers in Surgery
and Medicine, Medical Physics, Microcirculation, Nature Photonics, Optics Express, Optics and
Lasers in Engineering, Optics Letters, Physics in Medicine and Biology, Technology in Cancer
Research and Treatment
Societies:
American Society for Laser Medicine and Surgery: Fellow; 2004-2007 Board of Directors; 2004-pres.
Research and Development Committee; 2005-2006 Ethics Committee; 2002,3,4,5,6,7 Session
chair Annual meeting
Biomedical Engineering Society: Member; 2000-pres. Faculty Advisor UA student chapter; 2003 Session
chair for Annual Meeting
Institute of Electrical and Electronic Engineers: Member; 2004 Committee IEEE LEOS annual meeting
Optical Society of America: Member; 2003 Optics in Biology and Medicine vice-chair; 2003, 2005 Session
chair annual meeting

Curriculum Vitae Jennifer Kehlet Barton
SPIE: Fellow; 2001 Co-chair, SPIE Opto-Southwest, Conference on Optical Imaging in Medicine;
2003,4,5,6,7,8 Session chair and program committee, Photonics West; 2005-pres. Co-chair
International Biomedical Optics Society; 2005,7 Session chair and program committee European
Conferences on Biomedical Optics; 2006 Women in Optics Calendar of Days; 2006 Featured in
“Your Society” Member Guide; 2006 Essay in SPIE “50 Years” publication
Awards:
1996,1997 NASA/Texas Space Grant Fellowship
1996,1997 A.D. Hutchinson/University of Texas Endowment Fellowship
1997 SPIE D.J. Lovell Scholarship
1998 Research Paper Award, 18th Ann. Mtg, ASLMS
1999 Award for Excellence at the Student Interface, College of Engineering and Mines
Publications:
Peer Reviewed Articles:
Barton JK, Milner TE, Pfefer TJ, Nelson JS, Welch AJ: Optical low coherence reflectometry to enhance
Monte Carlo modeling of skin. Journal of Biomedical Optics, 2(2):226-234, 1997.
Pfefer TJ, Barton JK, Chan EK, Ducros MG, Sorg BS, Welch AJ: A three dimensional modular adaptable grid
numerical model for light propagation during laser irradiation of skin tissue. Journal of Selected Topics in
Quantum Electronics, 2(4):934-942, 1997.
Wright CHG, Barton JK, Protsenko DE, Rylander HG, Welch AJ: Anomalous reflectance of laser-induced
retinal lesions. Journal of Selected Topics in Quantum Electronics, 2(4):1035-1040, 1997.
Izatt JA, Kulkarni MD, Yazdanfar S, Barton JK, Welch AJ: In vivo bidirectional Doppler flow imaging of
picoliter blood volumes using optical coherence tomography. Optics Letters, 22(18):1439-1441, 1997.
Choi B, Barton JK, Chan EK, Welch AJ: Imaging of the irradiation of skin with a clinical CO2 laser system:
Implications for laser skin resurfacing: Lasers in Surgery and Medicine, 23:185-193, 1998.
Barton JK, Pfefer TJ, Welch AJ, Smithies DJ, Nelson JS, van Gemert MJC: Optical Monte Carlo modeling of
a true port wine stain anatomy. Optics Express 2, 391, 1998.
Barton JK, Izatt JA, Welch AJ: Investigating pulsed dye laser-blood vessel interaction with color Doppler
optical coherence tomography. Optics Express 2:251-256, 1998.
Barton JK, Izatt JA, Kulkarni MD, Yazdanfar S, and Welch AJ: Three-dimensional reconstruction of blood
vessels from in vivo color Doppler optical coherence tomography images. Dermatology, 198:355-361,
1999.
Barton JK, Hammer DX, Pfefer TJ, Lund TJ, Stuck BE, Welch AJ: Simultaneous irradiation and imaging of
cutaneous blood vessels. Lasers in Surgery and Medicine, 24:236-243, 1999.
Choi B, Chan EK, Barton JK, Thomsen SL, Welch AJ: Thermographic and histological evaluation of laser skin
resurfacing scans. IEEE Journal of Selected Topics in Quantum Electronics, 5:1116-1126, 1999.
Vargas G, Chan EK, Barton JK, Rylander HG, Welch AJ: Use of an agent to reduce scattering in skin.
Lasers in Surgery and Medicine, 24:133-141 1999.
Pfefer TJ, Barton JK, Smithies DJ, Milner TE, Nelson JS, van Gemert MJC, Welch AJ: Modeling laser
treatment of port wine stains with a computer-reconstructed biopsy. Lasers in Surgery and Medicine,
24:151-166, 1999.
Barton JK, Vargas G, Pfefer TJ, Welch AJ: Laser fluence for permanent damage of cutaneous blood vessels.
Photochemistry and Photobiology, 70:916-920, 1999.
Barton JK, Rollins A, Yazdanfar S, Pfefer TJ, Westphal V, Izatt JA: Photothermal coagulation of blood
vessels: a comparison of high-speed optical coherence tomography and numerical modeling. Physics in
Medicine and Biology, 46:1665-1678, 2001.
Barton JK, Frangineas G, Pummer H, Black JF: Cooperative phenomena in two-pulse, two-color laser
photocoagulation of cutaneous blood vessels. Photochemistry and Photobiology, Jun;73(6):642-50, 2001.
Barton JK, Popok D, Black JF: Thermal analysis of blood undergoing laser photocoagulation. IEEE Journal
of Selected Topics in Quantum Electronics, 7:936-943, 2001.
Wong RC, Yazdanfar S, Izatt JA, Kulkarni M, Barton JK, Welch AJ, Willis J, Sivak MV: Visualization of
subsurface blood vessels by color Doppler-optical coherence tomography in rats: before and after
hemostatic therapy. Gastrointestinal Endoscopy, 55(1):88-95, 2002.
Hansen KA, Weiss JA, Barton JK: Recruitment of tendon crimp with applied tensile strain. Journal of
Biomechanical Engineering, 124:72-77, 2002.

Curriculum Vitae Jennifer Kehlet Barton
Rollins AM, Yazdanfar S, Barton JK, and Izatt JA: Real-time in vivo color Doppler optical coherence
tomography. Journal of Biomedical Optics, 7:123-129, 2002.
Barton JK, Hoying JB, Sullivan CJ: Use of microbubbles as an optical coherence tomography contrast agent.
Acad Radiol, 9 Suppl 1:S52-5, 2002.
Gossage K, Tkaczyk T, Rodriguez J, Barton JK: Texture Analysis of Optical Coherence Tomography Images:
Feasibility for Tissue Classification,” Journal of Biomedical Optics 8:570-575, 2003.
Loeb G, Barton JK: Optical Coherence Tomography for Morphological Imaging of Fruits. Transactions of the
American Society of Agricultural Engineering, 46:1751-1757, 2003.
Barton JK, Gossage KW, Xu W, Ranger-Moore J, Saboda K, Brooks CA, Duckett LD, Salache SJ, Warneke
JA, Alberts DS: Investigating sundamaged skin and actinic keratosis with optical coherence tomography: a
pilot study. Technology in Cancer Research and Treatment, 2:525-535, 2003.
Tumlinson AR, Hariri LP, Utzinger U, Barton JK: A miniature endoscope for simultaneous OCT-LIF
measurement. Applied Optics, 43:113-121, 2004.
Barton JK, Guzman F, Tumlinson AR: Dual modality instrument for simultaneous optical coherence
tomography imaging and fluorescence spectroscopy. Journal of Biomedical Optics, 9:618-623, 2004.
Alberding J, Barton JK, Wiley EB, Baldwin AL: Onset of pulsatile pressure causes transiently increased
filtration through artery wall, American Journal of Physiology, Heart Circ. Physiol., 286:H1827-35, 2004.
Loo C, Lin A, Hirsch L, Lee M, Barton JK, Halas N, West J, Drezek R: Nanoshell-enabled photonics-based
imaging and therapy of cancer, Technology in Cancer Research and Treatment, 3:33-40 2004.
Scepanovic M, Castillo JE, Barton JK, Mathine D, Kostuk RK, Sato A: Design and processing of high-density
single-mode fiber arrays for imaging and parallel interferometer applications, Appl. Opt. 43: 4150-4156,
2004.
Brewer M, Utzinger U, Barton JK, Hoying JB, Kirkpatrick ND, Brands WR, Davis JR, Hunt K, Stevens SJ,
Gmitro AF, Imaging of the Ovary, Technology in Cancer Research and Treatment, 3: 617-628, 2004.
Kariya R, Mathine DL, Barton JK, Analog CMOS Circuit Design and Characterization for Optical Coherence
Tomography Signal Processing, IEEE Transactions on Biomedical Engineering, 51:2160-3, 2004.
Black JF and Barton JK, “Chemical and Structural Changes in Blood Undergoing Laser Photocoagulation,”
Photochemistry and Photobiology, 80:89-97, 2004.
Black JF, Wade N, Barton JK, “Mechanistic comparison of blood undergoing laser photocoagulation at 532
and 1,064 nm,” Lasers Surg. Med. 36:155-165, 2005.
Barton JK, Stromski S, "Flow measurement without phase information in optical coherence tomography
images," Optics Express, 13:5234-5239, 2005.
Alberding JP, Baldwin AL, Barton JK, Wiley E, “Effects of pulsation frequency and endothelial integrity on
enhanced arterial transmural filtration produced by pulsatile pressure,” Am J Physiol Heart Circ Physiol.
289(2):H931-7 2005.
Gossage KW, Smith CM, Kanter EM, Hariri LP, Stone AL, Rodriguez JJ, Williams SK, Barton JK, “Texture
analysis of speckle in optical coherence tomography images of tissue phantoms", Physics in Medicine and
Biology, 51:1563-1575, 2006.
Hariri LP, Tumlinson AR, Wade NH, Besselsen D, Utzinger U, Gerner E, Barton JK, “Endoscopic optical
coherence tomography and laser induced fluorescence spectroscopy in a murine colon cancer model,”
Lasers in Surgery and Medicine, 38:305-313, 2006.
Xu W, Bonnema GT, Gossage KW, Wade NH, Medford J, Bartonm JK, “Customized analog circuit design for
fiber based optical coherence microscopy,” Review of Scientific Instruments 77: 016104, 2006.
McNally J, Kirkpatrick N, Hariri LP, Tumlinson AR, Besselsen D, Gerner E, Urs Utzinger U, Barton J., “Task
Based Imaging of Colon Cancer in a Mouse Model (Apc Min/+ ),” Applied Optics, 45: 3049-3062, 2006.
Kanter EM, Walker RM, Marion SL, Brewer M, Hoyer PB, Barton JK, “Dual modality imaging of a novel rat
model of ovarian carcinogenesis,” Journal of Biomedical Optics, Vol. 11, 041123, 2006.
Agrawal A, Huang S, Wei A, Lin H, Lee M, Barton JK, Drezek R, Pfefer J, “Quantitative evaluation of optical
coherence tomography signal enhancement with gold nanoshells,” Journal of Biomedical Optics, Vol. 11,
041121, 2006.
Tumlinson AR, Barton JK, Povazay B, Sattman H, Unterhuber A, Leitgeb RA, Drexler W, “Endoscope-tip
interferometer for ultrahigh resolution frequency domain optical coherence tomography in mouse colon,”
Optics Express, 14: 1878-1887, 2006.
Xu W, Mathine DL, Barton JK, “High-gain differential CMOS transimpedance amplifier with on-chip buried
double junction photodiode,” Electronics Letters 42(14):803-5, 2006.

Curriculum Vitae Jennifer Kehlet Barton
Tumlinson AR, Povazay B, Hariri LP, McNally J, Unterhuber A, Hermann B, Sattmann H, Drexler W, Barton
JK, “In vivo ultrahigh-resolution optical coherence tomography of mouse colon with an achromatized
endoscope,” Journal of Biomedical Optics, 11:064003, 2006.
Cardinal KO, Bonnema GT, Hofer H, Barton JK, Williams SK, "Tissue Engineered Vascular Grafts as In Vitro
Blood Vessel Mimics to Evaluate Endothelialization of Intravascular Devices" Tissue Engineering, 12:3431-
8, 2006.
Luo Y , Castillo J, Arauz L, Barton JK, Kostuk RK, "Coupling and crosstalk effects in high density fiber
imaging," Applied Optics 46:253-261, 2007.
Hariri LP, Tumlinson AR, Wade NH, Besselsen DG, Utzinger U, Gerner EW, Barton JK, “Ex Vivo Optical
Coherence Tomography and Laser-induced Fluorescence Spectroscopy Imaging of Murine
Gastrointestinal Tract,” Comparative Medicine, 57 02 04, 2007.
Bonnema GT, Cardinal KO, McNally JB, Williams SK, Barton JK, “Assessment of Blood Vessel Mimics with
Optical Coherence Tomography,” Journal of Biomedical Optics, 12:024018, 2007.
Troutman T, Barton JK, Romanowski M, “Optical Coherence Tomography with Plasmon Resonant Nanorods
of Gold,” Optics Letters, 32:1438-1440, 2007.
Hariri LP, Qiu L, Tumlinson AR, Besselsen DG, Gerner EG, Ignatenko N, Povazay B, Hermann B, Sattmann H,
McNally J, Unterhuber, Drexler W, Barton JK, “Serial endoscopy in azoxymethane treated mice using
ultrahigh resolution optical coherence tomography,” Cancer Biology and Therapy, 6:11 1-10, 2007.
Korde V, Bonnema G, Xu W, Krishnamurthy C, Ranger-Moore J, Saboda K, Slayton L, Salasche S, Warneke
J, Alberts D, and Barton JK, “Using Optical Coherence Tomography to Evaluate Skin Sun Damage and
Precancer,” Lasers in Surgery and Medicine, 39:687-695, 2007.
Luo Y, Arauz L, Castillo J, Barton JK, Kostuk R, “Parallel Optical Coherence Tomography System” Applied
Optics, 46(34):8291-7, 2007.
Xu W, Mathine DL, Barton JK, “Analog CMOS design for optical coherence tomography signal detection and
processing,” IEEE Transactions on Biomedical Engineering, 55(2):485-9, 2008.
Tumlinson AR, Hofer B, Winkler A, Povazay B, Drexler W, Barton JK, Inherent homogenous media dispersion
compensation in frequency domain optical coherence tomography by accurate “k-sampling,” Applied Optics
47(5):687-93, 2008.
Black KC, Kirkpatrick ND, Troutman TS, Xu L, Vagner J, Gillies RJ, Barton JK, Utzinger U, Romanowski M,
“Gold nanorods targeted to delta opioid receptor: plasmon-resonant contrast and photothermal agents,”
Molecular Imaging 7(1):50-7, 2008.
Luo Y, Gelsinger PJ, Barton JK, Barbastathis G, Kostuk RK, “Optimization of multiplexed holographic gratings
in PQ-PMMA for spectral-spatial imaging filters,” Opt Lett 33:566-8, 2008.
Vargas G, Barton JK, Welch AJ “The Use of Hyper-osmotic Chemical Agent to Improve the Laser Treatment
of Cutaneous Vascular Lesions,” Journal of Biomedical Optics, 13:021114, 2008.
Troutman T, Barton JK, Romanowski MR “Biodegradable Plasmon Resonant Nanoshells,” Advanced
Materials, 20:2604-2608, 2008.
Arauz LJ, Luo Y, Castillo JE, Barton JK, Kostuk RK “Fiber Array Fabrication Technique for 15µm Diameter
Single Mode Fibers,” Optical Engineering, 47: 074002, 2008.
Bonnema GT, O’Halloran Cardinal K, Williams SK, Barton JK “An automatic algorithm for detecting stent
endothelialization from volumetric optical coherence tomography datasets,” Physics in Medicine and
Biology, 53:3083-3098, 2008.
Luo Y, Gelsinger-Austin PJ, Watson JM, Barbastathis G, Barton JK, Kostuk RK, “Laser-induced fluorescence
imaging of subsurface tissue structures with a volume holographic spatial-spectral imaging system,” Opt
Lett. 33(18):2098-2100, 2008.
Zhang Y, Davidson BR, Stamer WD, Barton JK, Marmorstein L, Marmorstein AD, “Enhanced inflow and
outflow rates despite lower IOP in Bestrophin-2 deficient mice,” Invest Ophthalmol Vis Sci. 50:765-70,
2009.
Hoyer PB, Davis JR, Bedrnicek JB, Marion SL, Christian PJ, Barton JK, Brewer MA, "Ovarian neoplasm
development by 7,12-dimethylbenz[a]anthracene (DMBA) in a chemically-induced rat model of ovarian
failure,” Gynecological Oncology, 112:610615, 2009.
Book Chapters:
J.K. Barton, A. Tumlinson, U. Utzinger, “Combined Endoscopic Optical Coherence Tomography and Laser

Curriculum Vitae Jennifer Kehlet Barton
Induced Fluorescence,” in Optical Coherence Tomography: Technology and Applications, W. Drexler and
J. Fujimoto, eds., Springer, 2008.
J.K Barton, “Dynamic Optical Properties,” in Optical-Thermal Response to Laser-Irradiated Tissues, A.J.
Welch and M.J.C. van Gemert, eds. to be published in 2009.
Reviews, comments, and other publications:
J.A. Izatt, M.D. Kulkarni, K. Kobayashi, M.V. Sivak, J.K. Barton, and A.J. Welch, "Optical Coherence
Tomography for Biodiagnostics," Optics and Photonics News 8:41-47, 1997.
J.K. Barton, "Optical Coherence Tomography," McGraw-Hill 2000 Yearbook of Science and Technology,
McGraw-Hill, New York, NY, 2000.
J.F. Black and J.K. Barton “Two-photon laser techniques for diagnostic and therapeutic medicine,” DOPS-
NYT Journal of the Danish Optical Society, 4:29-33 2001.
J.K. Barton “Big Images Small Features.” Nature Photonics 1:684-685, 2007.
Full-length Manuscript Conference Proceedings:
E.K. Chan, B. Amini, J.K. Barton, A.J. Welch, S.L. Thomsen, R.C. Stoneman, L. Esterowitz. “Wavelength
dependency of soft tissue coagulation with a tunable cw laser,” proc. SPIE, 2581, p. 102-113, 1996.
J.K. Barton, J.A. Izatt, M.D. Kulkarni, A.J. Welch, "Three-dimensional reconstruction of rat dermal blood
vessels in vivo," proc. SPIE, v. 2970, p. 266-275, 1997.
A.J. Welch, E.K. Chan, J.K. Barton, B. Choi, S. L. Thomsen. “Infrared imaging of CO2 laser resurfacing,” proc.
SPIE, 2970, p. 305-311, 1997.
T.J. Pfefer, J.K. Barton, E.K. Chan, M.G. Ducros, B.S. Sorg, T.E. Milner, J.S. Nelson, A.J. Welch. “Adaptable
three-dimensional Monte Carlo modeling of imaged blood vessels in skin,” proc. SPIE, 2975 p. 2-13, 1997.
J.K. Barton J.A. Izatt, A.J. Welch, "Investigating laser-blood vessel interaction with color Doppler optical
coherence tomography." proc. SPIE, 3251 p. 102-113, 1998.
S. Yazdanfar, M.D. Kulkarni, R.C.K. Wong, M.V. Sivak, J. Willis, J.K. Barton, A.J. Welch, J.A. Izatt,
"Diagnostic blood flow monitoring during therapeutic interceptions using color Doppler optical coherence
tomography," proc. SPIE, 3251 p. 126-132, 1998.
B. Choi, J.K. Barton, E.K. Chan, S.L. Thomsen, A.J. Welch, "Infrared imaging of CO2 laser ablation:
Implications for laser skin resurfacing," proc. SPIE, 3245 p. 344-355, 1998.
T.J. Pfefer, J.K. Barton, D. Smithies, T.E. Milner, M.J.C. van Gemert, J.S. Nelson, A.J. Welch, "Laser
Treatment of Port Wine Stains: Three-Dimensional Simulation Using Biopsy-Defined Geometry in an
Optical-Thermal Model," proc. SPIE, 3245 p. 322-333, 1998.
G. Vargas, J.K. Barton, B. Choi, J.A. Izatt, A.J. Welch, "Assessing vessel damage with color Doppler optical
coherence tomography," proc. SPIE, 3598, p.185-194, 1999.
J.K. Barton, D.B. Dal Ponte, S/K. Williams, B.K. Ford, M.R. Descour, “Imaging vascular implants with optical
coherence tomography,” proc. SPIE Vol. 3915, p. 229-236, 2000.
K.A. Hansen, J.K. Barton, J.A. Weiss, Optical coherence tomography imaging of collagenous tissue
microstructure proc. SPIE Vol. 3914, p. 581-587, 2000.
G. Vargas, J.K. Barton, A.J. Welch, “Selective photocoagulation of cutaneous blood vessels with evaluation of
vessel damage by color Doppler optical coherence tomography,” proc. SPIE 3907:136-142, 2000.
J.K. Barton, A.M. Rollins, S. Yazdanfar, T.J. Pfefer, V. Westphal, J.A. Izatt, “Optical-thermal model verification
by high-speed optical coherence tomography,” proc. SPIE Vol. 4251, p. 174-182, 2001.
F. Guzman, J.K. Barton, “Dual OCT/spectroscopy system for identification of vascular pathology,” proc. SPIE
Vol. 4244, p. 413-418, 2001.
J.F. Black, J.K. Barton, “Cooperative phenomena in two-pulse two-color laser photocoagulation of cutaneous
blood vessels, proc. SPIE vol. 4244, p. 13-24, 2001.
J.K. Barton, S.J. Loui, J.F. Black, “Optical and magnetic resonance changes in photothermally coagulating
blood,” proc. SPIE Vol. 4609:10-19, 2002.
T.S. Tkaczyk, K.W. Gossage, J.K. Barton, “Speckle image properties in optical coherence tomography,” proc.
SPIE Vol. 4619, p. 59-70, 2002.
F. Guzman, J.K. Barton, “Catheter-based instrument for simultaneous OCT imaging and fluorescence
spectroscopy,” proc. SPIE Vol. 4609, p. 430-437, 2002.
K.W. Gossage, T.S. Tkaczyk, J.K. Barton, “Using optical coherence tomography to evaluate glaucoma implant
healing response in rabbit eyes,” proc. SPIE Vol. 4611, p. 37-47, 2002.

Curriculum Vitae Jennifer Kehlet Barton
K.W. Gossage, T.S. Tkaczyk, J.J. Rodriquez, J.K. Barton, “Texture analysis for tissue classification of optical
coherence tomography images,” proc. SPIE Vol. 4958, p. 109-117, 2003.
A. Tumlinson, L. Hariri, J.K. Barton, “Miniature endoscope for a combined OCT-LIF system,” proc. SPIE Vol.
4956, p. 129-138, 2003.
J.K. Barton, N.J. Halas, J.L West, R.A. Drezek, “Nanoshells as an Optical Coherence Tomography Contrast
Agent,” proc. SPIE Vol 5316, p. 96-106, 2004.
K.W. Gossage, C.M. Smith, E.M. Kanter, L.P. Hariri, A.L. Stone, J.J. Rodriguez, S.K. Williams, J.K. Barton,
“Texture analysis of speckle in optical coherence tomography images of tissue phantoms,” proc. SPIE Vol.
5318, p. 140-150, 2004.
A.R. Tumlinson, J. McNally, A. Unterhuber, B. Hermann, H. Sattmann, L. Hariri, W. Drexler, J.K. Barton,
"Endoscopic ultrahigh-resolution OCT for in vivo imaging colon disease model mice," proc. SPIE, vol. 5692,
p. 307-315, 2005.
L. Hariri, A. Tumlinson, N. Wade, D. Besselsen, U. Utzinger, E. Gerner, J.K. Barton. "Ex vivo optical
coherence tomography and laser induced fluorescence spectroscopy imaging of murine gastrointestinal
tract," proc. SPIE, vol. 5692, p. 295-306, 2005.
J.K. Barton, S. Stromski. “Flow measurement using speckle in optical coherence tomography imaging,” Proc.
SPIE, vol. 5690, p. 245-256, 2005.
W. Xu, G. Bonnema, K. Gossage, N. Wade, J. Medford, J.K. Barton. “A low cost customized analog circuit
design for optical coherence microscopy,” proc. SPIE vol. 5692, p. 283-294, 2005.
E. Kanter, R. Walker, S. Marion, P. Hoyer, J.K. Barton, “Use of multiple imaging modalities to detect ovarian
cancer,” proc. SPIE vol. 5686, p. 596-605, 2005.
L.P. Hariri, Z. Qiu, A.R. Tumlinson, D.G. Besselsen, E.W. Gerner, N. Ignatenko, B. Považay, B. Hermann, H.
Sattmann, J. McNally, A. Unterhuber, W. Drexler, and J K. Barton, “Serial endoscopy in azoxymethane
treated mice using ultra-high-resolution optical coherence tomography” proc. SPIE vol. 6432, 643208 2007.
L.J. Arauz, Y. Luo, J.E. Castillo, R.K. Kostuk, and J.K. Barton, “10-channel fiber array fabrication technique for
parallel optical coherence tomography system,” proc. SPIE vol. 6429, 64292H 2007.
A.R. Tumlinson, B. Hofer, B. Považay, A. Winkler, W. Drexler, and J.K. Barton, “Inherent media dispersion
compensation by FD-OCT,” proc. SPIE vol. 6429, 64291C 2007.
J.K. Barton, S. Tang, R. Lim, B.J. Tromberg, “Simultaneous Optical Coherence and Multiphoton Microscopy of
Skin-Equivalent Tissue Models,” proc. SPIE vol. 6627, 66270X, 2007.
V.R. Korde, J Bartels, J Ranger-Moore, J.K. Barton. Automatic segmentation of cell nuclei in bladder and skin
tissue for karyometric analysis. Biophotonics 2007: Optics in Life Science. proc. SPIE vol. 6633, 66330V,
2007.
A.R. Tumlinson, L.P. Hariri, W. Drexler, J.K. Barton, “Scatter sensitive microscopic techniques to identify
contrasting mucosal structures in ultrahigh-resolution optical coherence tomograms of mouse colon,” proc.
SPIE 6851, 68510A, 2008.
L.P.Hariri, Bonnema GT, Schmidt K, Hatch K, Brewer M, Barton JK, “Laparoscopic optical coherence
tomographic imaging of human ovarian cancer proc. SPIE vol. 6851, 685107, 2008.
Y. Luo, P.J. Gelsinger, J.K. Barton, G Barbastathis, R Kostuk, “Multiplexing volume holographic gratings for a
spectral-spatial imaging system”, proc. SPIE vol. 6912, 69120A, 2008.
A.W. Winkler, Rice PS, Troutman TS, Backer MV, Backer JM, Drezek RA, Romanowski M, Barton JK,
“Fluorescent and scattering contrast agents in a mouse model of colorectal cancer,” proc. SPIE, Vol. 6851,
68510L, 2008.
G.T. Bonnema, K.O. Cardinal, S.K. Williams, J.K. Barton Imaging stented tissue engineered blood vessel
mimics, proc. SPIE, Vol. 6858, 68580F, 2008.
Other conference proceedings
J.K. Barton, D. Smithies, M.J.C. van Gemert, J.S. Nelson, A.J. Welch, "Monte Carlo modeling of a true port
wine stain anatomy," Conference on Lasers and Electro-optics, Baltimore, MD, May 18-23, 1997.
J.A. Izatt, M.D. Kulkarni, J.K. Barton, A.J. Welch, "In vivo Doppler flow imaging of picoliter blood volumes using
optical coherence tomography," Conference on Lasers and Electro-optics, Baltimore, MD, May 18-23,
1997.
M.D. Kulkarni, J.A. Izatt, K. Kobayashi, S. Yazdanfar, R.C.K. Wong, M.V. Sivak, J.K. Barton, A.J. Welch,
"Optical coherence tomography: a novel tool for micron-resolution biomedical diagnostics," 19 th Annual
International Congress of the IEEE Engineering in Medicine and Biology Society, 883-886, 1997.

Curriculum Vitae Jennifer Kehlet Barton
J.A. Izatt, M.D. Kulkarni, S. Yazdanfar, R.C.K. Wong, J.K. Barton, A.J. Welch, "In vivo color Doppler optical
coherence tomography," OSA Annual Meeting, October 12-17, 1997.
J.K. Barton, J.B. Hoying, C.J. Sullivan, "Use of Microbubbles as an Optical Coherence Tomography Contrast
Agent," Contrast Media Research 1999 , Woodstock, VT, 9/12-17, 1999 (published in Academic
Radiology 9(S1): S52-S55, 2001).
J.K. Barton, G. Frangineas, H. Pummer, J.F. Black, “Two-Color Laser Photocoagulation of Cutaneous Blood
Vessels,” World Congress on Medical Physics and Biomedical Engineering, Chicago, IL, July 23-28, 2000.
Baldwin A L, Alberding J, Barton J K and Wiley E B, “Use of optical coherence tomography to measure
mechanical and transport properties of pulsing arterial walls," Proc. 2001 Bioengineering Conference,
ASME BED-Vol. 50:677-678.
T. Tkaczyk, J.K. Barton “Analysis of optical system influences on imaging results in optical coherence
tomography,” SPIE Opto-SW, Tucson, AZ, Sept. 17-18 2001.
J.K. Barton, J.F. Black, “Time-domain optical properties of laser irradiated blood,” SPIE Opto-SW, Tucson, AZ,
Sept. 17-18 2001.
Lin, A., Barton, J., Halas, N., and Drezek, R. "Nanoengineered Contrast Agents for Biophotonics" Advances in
Optics for Biotechnology, Medicine, and Surgery. Banff, Canada. August 2003.
J.K. Barton, S. Priya, N. Wade, J.F. Black, “Dynamic optical properties of blood irradiated at 1064 nm,” Annual
meeting of the ASLMS, Anaheim, CA, April 2003.
J.K. Barton, L. Hariri, A. Tumlinson, “Combined optical coherence tomography and fluorescence spectroscopy
for characterization of tissues,” IEEE LEOS Ann Mtg Proc. Vol. 1, p. 458-459, 2003.
J. K. Barton, S. Priya, N. Wade, J. F. Black, “Dynamic optical properties of blood irradiated at 1064 nm,” Joint
International Laser Meeting, Edinburgh, Scotland, Sept 21-23 2003.
G.T. Bonnema. S.K. Williams, J.K. Barton, “Imaging vascular implant development with optical coherence
tomography,” IEEE LEOS Ann Mtg Proc. Vol. 2, p. 763-764, 2004.
R. K. Kostuk, M. Scepanovic, and J. E. Castillo, ``Low coherence interferometer for accurate fiber length
measurement and fiber array device fabrication,’’ 88 th OSA Annual Meeting, p. 95, Rochester, N. Y., 10-14
October, 2004.
K. O’Halloran, Bonnema G, Barton J, Williams SK. “Stent Evaluation in a Blood Vessel Mimic.” Surfaces in
Biomaterials: BioInterface; October 2005.
Y. Luo, J. E. Castillo, L. J. Arauz, J. K. Barton, and R. K. Kostuk, ``Modeling and experimental measurement of
scattering effects in a high parallel fiber imaging system,’’ 89 th OSA Annual Meeting, p. 100, Tucson, AZ.,
16-20 October, 2005.
J. E. Castillo, Y. Luo, L. J. Arauz, M. Scepanovic, J. K. Barton, and R. K. Kostuk, ``Ten channel interferometer
for endoscopic parallel optical coherence tomography,’’ 89 th OSA Annual Meeting, p. 94, Tucson, AZ., 16-
20 October, 2005.
Y. Luo, L. J. Arauz, J. E. Castillo, J. K. Barton, and R. K. Kostuk, ``Coherent proximity sensor with high density
fiber array,’’ 90 th OSA Annual Meeting, paper FThN1, Rochester, N.Y., 8-12 October, 2006.
V. Korde, Chetankumar Krishnamurthy,James Ranger-Moore, David S. Alberts, Jennifer K. Barton, "Optical
Coherence Tomography as an Aid in Chemoprevention of Skin Cancer, Lasers in Surgery and Medicine,
38(S18) p. 14, 2006.
G.T. Bonnema, Cardinal KO, Williams SK, Barton JK. “Imaging Blood Vessel Mimics with Optical Coherence
Tomography” American Society for Laser Medicine and Surgery Annual Meeting; April 2006.
K.O. Cardinal, Bonnema GT, Barton JK, Williams SK. “Effect of Flow on Tissue Responses to Intravascular
Stents.” Biomedical Engineering Society: Unlimited Horizons; October 2006.
L.J. Arauz, Y. Luo, J. Castillo, R. Kostuk, J. Barton, “10-Channel fiber array fabrication technique for Parallel
Optical Coherence Tomography System,” Photonics West BIOS 2007 Conference, [6429-88], 20-25
January 2007, San Jose, CA.
Patents
6,275,726 E.K. Chan, J.K. Barton, A.J. Welch, “Methods of enhanced light transmission through turbid
biological media,” August 14, 2001
6,766,187 J.F. Black and J.K. Barton, “Method for detecting coagulation in laser treatment of blood vessels”,
July 20, 2004

Curriculum Vitae Jennifer Kehlet Barton
6,942,663 G. Vargas, J.K. Barton, E.K. Chan, T.E. Milner, A.J. Welch, “Laser treatment of cutaneous vascular
lesions,” September 13, 2005
PCT/AT2006/000277 A. Tumlinson, W. Drexler, J.K. Barton, “Optical Coherence Tomography Endoscope
Utilizing a Distally Integrated Interferometer”
Research Projects Ongoing or Recently Completed:
“Optical Imaging of Ovarian Carcinogenesis in a Novel Rat Model”
Principal Investigator: Jennifer Barton
Type: Research Grant 12/12/06-12/11/11
Agency: National Institutes of Health/ NCI R01 CA119200
Total Direct Costs: $875,000 Effort: 15%
A novel post-menopausal rat model of ovarian cancer will be developed under this grant and imaged with
optical coherence tomography, optical coherence microscopy, and laser-induced fluorescence. Technology
development will include miniature OCT and OCM probes.
“Optical Holographic Spatial-Spectral Imaging”
Principal Investigator: Raymond Kostuk (Barton Co-investigator)
Type: Research Grant 08/25/06-07/31/08 ncx 07/31/09
Agency: National Institutes of Health/ NCI R21 CA118167
Total Direct Costs: $154,400 Effort 7%
This grant funds development of an imaging system capable of simultaneously obtaining three spatial and one
spectral dimensions.
“Dual-modality system for imaging colon cancer in mice”
Principal Investigator: Jennifer Barton
Type: Research Grant 07/01/04-04/30/09 ncx 2010 (renewal 2.6%)
Agency: National Institutes of Health/NCI R01 CA109835
Total Direct Costs $1,126,022 Effort 20%
This grant funds development of a dual modality imaging system (optical coherence tomography and
fluorescence spectroscopy) and the application of this system to minimally invasive imaging of mouse colon
cancer models.
“Chemoprevention of Skin Cancer”
Principal Investigator: David Alberts (Barton investigator)
Type: Program Project Grant 07/01/04-06/30/09
Agency: National Institutes of Health/NCI P01 CA27502
Total Direct Costs: $14,403,950 Effort: 2%
Barton’s role in the grant is to develop optical coherence tomography as a non-invasive biomarker for skin
sundamage and chemopreventive agent efficacy.
“Cardiovascular Biomedical Engineering”
Principle Investigator: Jennifer Barton
Type: Training Grant 04/01/00-06/30/11
Agency: National Institutes of Health/NHLBI T32 HL007955
Total Direct Costs: Approximately $210,000/year
This grant funds student training in the field of cardiovascular biomedical engineering
“Molecular Targeted Imaging in Colon Cancer” (Past)
Principle Investigator: Joseph Backer, SibTec, Inc. (Barton subcontract PI)
Type: SBIR Phase I 10/01/07-03/31/08 ncx 09/30/08
Agency: National Institutes of Health/ NCI R43 CA132528
Total Direct Costs: $150,000 Effort: 10% (for six months)

Curriculum Vitae Jennifer Kehlet Barton
This grant funds development of a fluorescence contrast agent targeted to the VEGF receptor. The subcontract
is to image this agent in a mouse model using endoscopic OCT/LIF
“Metrology Applications of OCT” (Past)
Principle Investigator: Jennifer Barton
Type: Contract 4/1/07-3/31/09
Company: CIBA Vision
Total Direct Costs: $49,500 (y1)+ $49,983 (y2) Effort: 1%
This contract covers efforts related to developing automated metrology of contact lenses
“Novel Superluminescent LEDs and Ultrahigh-resolution OCT for medical imaging applications” (Past)
Dual PI: Jennifer Barton, together with Yong-Hang Zhang, Arizona State University
Type: Research Grant 4/1/07-3/31/09
Agency: ASU-UA Collaborative on Biomedical Research
Total Direct Costs: $325,955 Effort: 5%
A new class of SLED light sources will be developed for optical coherence tomography applications, with broad
bandwidth and high power. They will be tested in a broadband OCT system with various tissue samples.
“Advanced Intravital Microscope” (Past)
Co-PI: Jennifer Barton (PI: Urs Utzinger)
Type: Shared Instrumentation Grant 04/01/07-03/31/08 ncx 03/31/09
Agency: National Institutes of Health/NCRR S10 RR23737
Total Direct Costs: $457,779
This grant will support the purchase of components to create an advanced intravital microscope, with
multiphoton imaging capabilities and the ability to measure tissue cultures and small animals.
“Advanced Intravital Microscope” (SFA supplement) (Past)
Dual PI: Jennifer Barton and Urs Utzinger
Type: Bridge Fund Grant 05/07/07-05/06/08
Agency: Science Foundation Arizona
Total Direct Costs: $45,752
This grant supplements the NIH award to build an advanced intravital microscope.
“Contrast Agents for Optical Coherence Tomography” (Past)
Principal Investigator: Marek Romanowski (Barton Co-investigator)
Type: Research Grant 07/01/04-06/30/07
Agency: Arizona Disease Control and Research Commission/ 9-002
Total Direct Costs: $250,000 Effort: 5%
This grant funds creation of liposome-scaffold, gold nanoparticles for OCT imaging contrast.
“Imaging the Vascular Response to Implants” (Past)
Principal Investigator: Jennifer Barton
Type: Independent Scientist Award 07/01/02-06/30/07
Agency: National Institutes of Health/NIBIB K02 EB000163
Total direct costs: $448,250 Effort 75%
This independent scientist award provides salary support and relief from some teaching/service activities, so
that more time can be spent on research.
“Parallel Optical Coherence Tomography for Endoscopic Imaging” (Past)
Principal Investigator: Jennifer Barton
Type: Research Grant 10/01/02-03/31/07
Agency: National Institutes of Health/NIBIB R01 EB01032
Total Direct Costs $690,642 Effort 25%

Curriculum Vitae Jennifer Kehlet Barton
This project fund development of a novel, parallel-imaging OCT system, using arrays of superluminescent
diodes, detectors, and CMOS processing channels. Feasibility will be tested by imaging the bladders of rabbits
and humans.
Classes Taught:
BME 417/517 Measurement and Data Analysis in Biomedical Engineering
ECE 340 Engineering Systems Analysis
ECE 4/529 Digital Signal Processing
OPTI/BME 630 Biomedical Imaging and Biophotonics
Students Graduated:
2000 Kristi Hansen, M.S. Biomedical Engineering (Engineer, Sebra, Tucson, AZ)
2001 Xianfeng Li, M.S. Electrical Engineering (Software Engineer, Kronos, Inc., Beaverton, OR)
2003 Alexandre Tumlinson, M.S. Optical Sciences (continued on to PhD)
2003 Steven Stromski, M.S. Optical Sciences (Engineer, Envisioneering, Inc., VA)
2003 Ajay Jain, M.S. Electrical Engineering (Conexant Systems, Hyderabad, India)
2004 Kirk Gossage, Ph.D. Biomedical Engineering, “Optical Coherence Tomography and Texture Analysis:
Non-Invasive Monitoring of Tissue Response to Glaucoma Implant” (Staff Scientist, Unilever,
Worcester, MA)
2005 Elizabeth Kanter, M.S. Biomedical Engineering (Postdoctoral Fellow- BrainHealth at University of Texas,
Dallas)
2005 James McNally, M.S. Optical Sciences (Engineer, Boston Scientific, Natick, MA)
2006 Wei Xu, Ph.D. Systems and Industrial Engineering, “Analog Signal Processing for Optical Coherence
Imaging Systems” (Engineer, Texas Instruments Inc., Tucson, AZ)
2007 Lida Hariri, Ph.D. Biomedical Engineering, “Optical Coherence Tomography and Laser Induced
Fluorescence in Mouse Models of Colorectal Cancer” (Resident, Harvard Medical School)
2007 Alexandre Tumlinson, Ph.D. Biomedical Engineering, “Ultrahigh-resolution endoscopic optical
coherence tomography for in vivo mouse colonoscopy” (Post-doctoral Associate, Cardiff University,
Wales)
2008 Garret Bonnema, Ph.D., Optical Sciences, “Imaging tissue engineered blood vessel mimics with optical
coherence tomography” (Senior Scientist, 4D, Dallas, TX)
2008 Paul Gelsinger, M.S. Optical Sciences (Optical Engineer, Edmund Optics, Barrington, NJ)
2009 Bryan Davidson, M.S. Electrical and Computer Engineering (Engineer, Amnis, Seattle, WA)
2009 Vrushali Korde, Ph.D. Optical Sciences (Research Specialist, U Arizona, Tucson, AZ)
Student Awards:
2001 Kirk Gossage, Arizona Graduate Imaging Fellowship
2001 Jonathan Alberding, NIH Predoctoral Fellowship for Students with Disabilities (co-sponsor)
2003 Alexandre Tumlinson, Arizona Graduate Imaging Fellowship
2004 Alexandre Tumlinson, Fulbright Comprehensive Grant (to University of Vienna)
2004 Garret Bonnema, Christopher Karl Schultz Memorial Scholarship
2005 James McNally, Arizona Graduate Imaging Fellowship
2005 Ross Walker, Outstanding Electrical Engineering Senior of the Class
2005 Ross Walker, International Engineering Consortium Award
2006, 2007 Amy Winkler, Achievement Rewards for College Scientists (ARCS) Fellowship
2006 Lida Hariri, P.E.O. Scholar Award
2006 Lida Hariri, Arizona Graduate Imaging Fellowship
2007 Vrushali Korde, SPIE Scholarship Award in Optical Science and Engineering
2007 Varun Bhartia, Outstanding College of Engineering Senior
2008 Jan Weichsel, Richard "Dick" Roberts Memorial Scholarship
2009 Amy Winkler, P.E.O. Scholar Award