A systematic review of the effectiveness of adalimumab

A systematic review of the effectiveness of adalimumab A systematic review of the effectiveness of adalimumab

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tumor necrosis factor therapy in the clinic. Arthritis Rheum 2005;52:3873–9. 94. Gomez-Puerta JA, Rodriguez-Cros JR, Graell E, Cañete JD, Albaladejo C, Sanmarti R. One-year efficacy of etanercept in rheumatoid arthritis patients who previously failed to infliximab. Arthritis Rheum 2004;50(Suppl):S190. 95. Keystone EC, Perruquet JL, Lidman RW, Stein B, Peller JS, Xia HA, et al. Switching anti-TNF therapy: real-world outcome of patients with rheumatoid arthritis who failed either infliximab or etanercept treatment and switched to another TNF inhibitor. Arthritis Rheum 2004;50(Suppl): S400–1. 96. Westhovens R, Wolfe F, Rahman MU, Han J, Yocum D. Infliximab dose escalation in patients with rheumatoid arthritis. Results from the START trial. Arthritis Rheum 2004;50(Suppl):S185–6. 97. van Vollenhoven RF, Brannemark S, Klareskog L. Dose escalation of infliximab in clinical practice: improvements seen may be explained by a regression-like effect. Ann Rheum Dis 2004; 63:426–30. 98. Stern R, Wolfe F. Infliximab dose and clinical status: results of 2 studies in 1642 patients with rheumatoid arthritis. J Rheumatol 2004;31:1538–45. 99. Schiff M, Mease P, Weinblatt M, Moreland L, Burge D. Randomized control trial of 25 mg vs. 50 mg Enbrel (etanercept) twice weekly in rheumatoid arthritis (RA) [abstract 1947]. Arthritis Rheum 2000;43(9 Suppl):S391. 100. Blumenauer B, Judd M, Wells G, Burls A, Cranney A, Hochberg M, et al. Infliximab for the treatment of rheumatoid arthritis [review]. Cochrane Database Syst Rev 2002;(3):CD003785. 101. Deeks JJ, Higgins JPT, Altman DG. Analysing and presenting results. In Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews for interventions 4.2.4 [updated March 2005]; Section 8. Chichester: John Wiley & Sons; 2005. 102. Breedveld FC, Kavanaugh AF, Cohen SB, Pavelka K, van Vollenhoven R, Perez JL, et al. Early treatment of rheumatoid arthritis (RA) with adalimumab (HUMIRA ® ) plus methotrexate vs. adalimumab alone or methotrexate alone. The PREMIER study [abstract L5]. Arthritis Rheum 2004;50:4096–7. 103. Codreanu C, Combe B, Fiocco U, Gaubitz M, Geusens PP, Kvien T, et al. Double-blind comparison of etanercept and sulfasalazine, alone and combined in active RA patients [abstract THU0120]. EULAR 2003; 2003. 104. Baumgartner SW, Paulus H, Burch F, Kivitz A, Dunn M, Kerr D, et al. A study to determine the safety of etanercept (Enbrel) in patients with rheumatoid arthritis who have concomitant © Queen’s Printer and Controller of HMSO 2006. All rights reserved. Health Technology Assessment 2006; Vol. 10: No. 42 comorbid conditions [abstract 1765]. Arthritis Rheum 2004;50(9 Suppl):S660–1. 105. Yocum D, Rahman MU, Han C, Bala M, Han J, Westhovens R. Infliximab rapidly improves all components of physical function assessed by the HAQ in patients with rheumatoid arthritis: results from the START trial [abstract]. Arthritis Rheum 2004;50(9 Suppl):S188–9. 106. Schattenkirchner M, Krüger K, Sander O, Rau R, Kroot EJ, van Riel PL, et al. Efficacy and tolerability of weekly subcutaneous injections of the fully human anti-TNF antibody D2E7 in patients with rheumatoid arthritis – results of a Phase I study. Arthritis Rheum 1998; 41(9 Suppl):S57. 107. van Riel P, Taggart A, Sany J, Gaubitz M, Garcia Lopez A, Korpela M, et al. Clinical efficacy and safety of the combination of etanercept plus methotrexate and etanercept alone in the treatment of rheumatoid arthritis patients with an inadequate response to methotrexate: the ADORE study [EULAR 2005 abstract]. Ann Rheum Dis 2005;64(Suppl III):437. 108. Goekoop-Ruiterman YPM, De Vries-Bouwstra JK, Allaart CF, Van Zeben D, Kerstens PJSM, Hazes JMW, et al. Clinical and radiological outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial. Arthritis Rheum 2005;52:3381–90. 109. Breedveld FC, Weisman MH, Kavanaugh AF, Cohen SB, Pavelka K, van Vollenhoven R, et al. The PREMIER study. A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum 2006;54:26–37. 110. van der Heijde D, Klareskog L, Rodriguez- Valverde V, Codreanu C, Bolosiu H, Melo-Gomes J, et al. Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis. Arthritis Rheum 2006; 54:1063–74. 111. Westhovens R, Yocum D, Han J, Berman A, Strusberg I, Geusens P, et al. The safety of infliximab, combined with background treatments, among patients with rheumatoid arthritis and various comorbidities: a large, randomized, placebo-controlled trial. Arthritis Rheum 2006; 54:1075–86. 112. Weinblatt ME, Keystone EC, Furst DE, Moreland LW, Weisman MH, Birbara CA, et al. Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA 131

tumor necrosis factor <strong>the</strong>rapy in <strong>the</strong> clinic. Arthritis<br />

Rheum 2005;52:3873–9.<br />

94. Gomez-Puerta JA, Rodriguez-Cros JR, Graell E,<br />

Cañete JD, Albaladejo C, Sanmarti R. One-year<br />

efficacy <strong>of</strong> etanercept in rheumatoid arthritis<br />

patients who previously failed to infliximab.<br />

Arthritis Rheum 2004;50(Suppl):S190.<br />

95. Keystone EC, Perruquet JL, Lidman RW, Stein B,<br />

Peller JS, Xia HA, et al. Switching anti-TNF<br />

<strong>the</strong>rapy: real-world outcome <strong>of</strong> patients with<br />

rheumatoid arthritis who failed ei<strong>the</strong>r infliximab<br />

or etanercept treatment and switched to ano<strong>the</strong>r<br />

TNF inhibitor. Arthritis Rheum 2004;50(Suppl):<br />

S400–1.<br />

96. Westhovens R, Wolfe F, Rahman MU, Han J,<br />

Yocum D. Infliximab dose escalation in patients<br />

with rheumatoid arthritis. Results from <strong>the</strong> START<br />

trial. Arthritis Rheum 2004;50(Suppl):S185–6.<br />

97. van Vollenhoven RF, Brannemark S, Klareskog L.<br />

Dose escalation <strong>of</strong> infliximab in clinical practice:<br />

improvements seen may be explained by a<br />

regression-like effect. Ann Rheum Dis 2004;<br />

63:426–30.<br />

98. Stern R, Wolfe F. Infliximab dose and clinical<br />

status: results <strong>of</strong> 2 studies in 1642 patients with<br />

rheumatoid arthritis. J Rheumatol 2004;31:1538–45.<br />

99. Schiff M, Mease P, Weinblatt M, Moreland L,<br />

Burge D. Randomized control trial <strong>of</strong> 25 mg vs.<br />

50 mg Enbrel (etanercept) twice weekly in<br />

rheumatoid arthritis (RA) [abstract 1947]. Arthritis<br />

Rheum 2000;43(9 Suppl):S391.<br />

100. Blumenauer B, Judd M, Wells G, Burls A,<br />

Cranney A, Hochberg M, et al. Infliximab for <strong>the</strong><br />

treatment <strong>of</strong> rheumatoid arthritis [<strong>review</strong>].<br />

Cochrane Database Syst Rev 2002;(3):CD003785.<br />

101. Deeks JJ, Higgins JPT, Altman DG. Analysing and<br />

presenting results. In Higgins JPT, Green S,<br />

editors. Cochrane handbook for <strong>systematic</strong> <strong>review</strong>s for<br />

interventions 4.2.4 [updated March 2005]; Section<br />

8. Chichester: John Wiley & Sons; 2005.<br />

102. Breedveld FC, Kavanaugh AF, Cohen SB,<br />

Pavelka K, van Vollenhoven R, Perez JL, et al. Early<br />

treatment <strong>of</strong> rheumatoid arthritis (RA) with<br />

<strong>adalimumab</strong> (HUMIRA ® ) plus methotrexate vs.<br />

<strong>adalimumab</strong> alone or methotrexate alone. The<br />

PREMIER study [abstract L5]. Arthritis Rheum<br />

2004;50:4096–7.<br />

103. Codreanu C, Combe B, Fiocco U, Gaubitz M,<br />

Geusens PP, Kvien T, et al. Double-blind<br />

comparison <strong>of</strong> etanercept and sulfasalazine, alone<br />

and combined in active RA patients [abstract<br />

THU0120]. EULAR 2003; 2003.<br />

104. Baumgartner SW, Paulus H, Burch F, Kivitz A,<br />

Dunn M, Kerr D, et al. A study to determine <strong>the</strong><br />

safety <strong>of</strong> etanercept (Enbrel) in patients with<br />

rheumatoid arthritis who have concomitant<br />

© Queen’s Printer and Controller <strong>of</strong> HMSO 2006. All rights reserved.<br />

Health Technology Assessment 2006; Vol. 10: No. 42<br />

comorbid conditions [abstract 1765]. Arthritis<br />

Rheum 2004;50(9 Suppl):S660–1.<br />

105. Yocum D, Rahman MU, Han C, Bala M, Han J,<br />

Westhovens R. Infliximab rapidly improves all<br />

components <strong>of</strong> physical function assessed by <strong>the</strong><br />

HAQ in patients with rheumatoid arthritis: results<br />

from <strong>the</strong> START trial [abstract]. Arthritis Rheum<br />

2004;50(9 Suppl):S188–9.<br />

106. Schattenkirchner M, Krüger K, Sander O, Rau R,<br />

Kroot EJ, van Riel PL, et al. Efficacy and<br />

tolerability <strong>of</strong> weekly subcutaneous injections <strong>of</strong><br />

<strong>the</strong> fully human anti-TNF antibody D2E7 in<br />

patients with rheumatoid arthritis – results <strong>of</strong> a<br />

Phase I study. Arthritis Rheum 1998;<br />

41(9 Suppl):S57.<br />

107. van Riel P, Taggart A, Sany J, Gaubitz M, Garcia<br />

Lopez A, Korpela M, et al. Clinical efficacy and<br />

safety <strong>of</strong> <strong>the</strong> combination <strong>of</strong> etanercept plus<br />

methotrexate and etanercept alone in <strong>the</strong><br />

treatment <strong>of</strong> rheumatoid arthritis patients with an<br />

inadequate response to methotrexate: <strong>the</strong> ADORE<br />

study [EULAR 2005 abstract]. Ann Rheum Dis<br />

2005;64(Suppl III):437.<br />

108. Goekoop-Ruiterman YPM, De Vries-Bouwstra JK,<br />

Allaart CF, Van Zeben D, Kerstens PJSM,<br />

Hazes JMW, et al. Clinical and radiological<br />

outcomes <strong>of</strong> four different treatment strategies in<br />

patients with early rheumatoid arthritis (<strong>the</strong> BeSt<br />

study): a randomized, controlled trial. Arthritis<br />

Rheum 2005;52:3381–90.<br />

109. Breedveld FC, Weisman MH, Kavanaugh AF,<br />

Cohen SB, Pavelka K, van Vollenhoven R, et al.<br />

The PREMIER study. A multicenter, randomized,<br />

double-blind clinical trial <strong>of</strong> combination <strong>the</strong>rapy<br />

with <strong>adalimumab</strong> plus methotrexate versus<br />

methotrexate alone or <strong>adalimumab</strong> alone in<br />

patients with early, aggressive rheumatoid arthritis<br />

who had not had previous methotrexate treatment.<br />

Arthritis Rheum 2006;54:26–37.<br />

110. van der Heijde D, Klareskog L, Rodriguez-<br />

Valverde V, Codreanu C, Bolosiu H, Melo-Gomes J,<br />

et al. Comparison <strong>of</strong> etanercept and methotrexate,<br />

alone and combined, in <strong>the</strong> treatment <strong>of</strong><br />

rheumatoid arthritis. Arthritis Rheum 2006;<br />

54:1063–74.<br />

111. Westhovens R, Yocum D, Han J, Berman A,<br />

Strusberg I, Geusens P, et al. The safety <strong>of</strong><br />

infliximab, combined with background treatments,<br />

among patients with rheumatoid arthritis and<br />

various comorbidities: a large, randomized,<br />

placebo-controlled trial. Arthritis Rheum 2006;<br />

54:1075–86.<br />

112. Weinblatt ME, Keystone EC, Furst DE,<br />

Moreland LW, Weisman MH, Birbara CA, et al.<br />

Adalimumab, a fully human anti-tumor necrosis<br />

factor alpha monoclonal antibody, for <strong>the</strong><br />

treatment <strong>of</strong> rheumatoid arthritis in patients<br />

taking concomitant methotrexate: <strong>the</strong> ARMADA<br />

131

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