Evaluation of liposomes coated with a pH responsive - University of ...

Table 1. The effect of Eudragit S100 addition upon the particle size (d50), size distribution
(span*) and zeta potential of liposomes. Each value represents the overall mean of three
independent experiments ± the standard error of the mean. *Span =
Concentration of
polymer coating
solution (%w/v) d(50) (µm) Span Zeta potential (mV)
0 7.7 ± 0.1 1.2 ± 0.1 63 ± 2.4
0.01 13.1 ± 2.1 2.3 ± 0.2 45 ± 2.4
0.025 22.0 ± 2.8 1.9 ± 0.4 28 ± 1.9
0.05 22.0 ± 3.4 2.4 ± 0.3 -28 ± 1.3
0.1 20.0 ± 1.7 2.0 ± 0.2 -30 ± 0.5
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