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Report in English with a Dutch summary (KCE reports 45A)

Report in English with a Dutch summary (KCE reports 45A)

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<strong>KCE</strong> <strong>reports</strong> vol.45 Screen<strong>in</strong>g for Colorectal Cancer 31<br />

100%<br />

90%<br />

80%<br />

70%<br />

60%<br />

50%<br />

40%<br />

30%<br />

20%<br />

10%<br />

was 57% <strong>in</strong> both males and females. Relative survival is a frequently used<br />

parameter <strong>in</strong> cancer epidemiology and forms a good approach to diseasespecific<br />

survival. The relative survival rates reflect an estimate of the expected<br />

survival of cancer patients, <strong>in</strong> which causes of death other than cancer have<br />

been left aside. Relative 5-year survival is calculated by divid<strong>in</strong>g the observed<br />

survival by the expected survival <strong>in</strong> a group of people <strong>with</strong> the same gender and<br />

age structure from the general population.<br />

Stage at diagnosis (TNM stag<strong>in</strong>g, 5th edition) is a strong predictor of survival43, 41,<br />

as illustrated by Figure 9 and Figure 10 show<strong>in</strong>g the observed and relative<br />

survival curves respectively of patients <strong>with</strong> CRC by stage.<br />

I II III IV Unknown<br />

0%<br />

0 12 24 36 48 60<br />

III<br />

Months<br />

Unknown<br />

VI<br />

Figure 9: Invasive colorectal cancers: observed survival by stage over<br />

5 years, 1997 2001 (source: Vlaams Agentschap Zorg en<br />

Gezondheid 39)<br />

I<br />

II

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