Report in English with a Dutch summary (KCE reports 45A)

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184 Screening for Colorectal Cancer: Appendices KCE reports vol.45 Nr. Title Issued by Year Familial Adenomatous Polyposis (FAP) & related 11 Follow-up na poliepectomie - Herziene richtlijn 189. Kwaliteitsinstituut voor de Gezondheidszorg (CBO - NL) 2002 1. Genetic counseling and testing is recommended for all family members with a familial history compatible with criteria for HNPCC, FAP or attenuated FAP. Follow-up frequency should be dictated by the outcome of such testing (recommendation level 3). 2. Such genetic counseling and testing is optional for all family members with a familial CRC history or a sporadic CRC at young age. In these cases colorectal surveillance after 3 y is advisable, however supported by little data (recommendation level 4). 2. Such genetic counseling and testing is optional for all family members with a familial CRC history or a sporadic CRC at young age. In these cases colorectal surveillance after 3 y is advisable, however supported by little data (recommendation level 4).3. There is no need for intensivated surveillance in case of colorectal polyps found at young age in combination with a negative familial history (recommendation level 4). Hereditary Non-Polyposis Colon Cancer (HNPCC) 1. Genetic counseling and testing is recommended for all family members with a familial history compatible with criteria for HNPCC, FAP or attenuated FAP. Follow-up frequency should be dictated by the outcome of such testing (recommendation level 3). 2. Such genetic counseling and testing is optional for all family members with a familial CRC history or a sporadic CRC at young age. In these cases colorectal surveillance after 3 y is advisable, however supported by little data (recommendation level 4).3. There is no need for intensivated surveillance in case of colorectal polyps found at young age in combination with a negative familial history (recommendation level 4). Personal history of CRC resection Not included Personal history of colonpolyps 1. CRC risk augments with number of adenomata (level 3). 2. Many adenomata found on follow-up colonoscopy were already present at indexcolonoscopy (level 3). 3. If 2 adenomata found at indexcolonoscopy first FU-colonoscopy at 6 y; if 3 polys, after 3 y (level 3). 4. Patients with cumulative 1 adenoma at 65 y no need for further FUcolonoscopy (level 3). 5. In case of 2 cumulative adenomata at 65 y: continue till 75 y. For 3: lifetime FU colonoscopy warranted (level 4). 6. A completely resected adenoma does not recur (level 4). 7. All resected polyps need histological examination before setting up a surveillance strategy (level 4). 8. DCBE for FU after polypectomy is indicated if endoscopist doubts complete removal of all polyps (level 4). 9. Patients with high risk family history of CRC: more frequent FU warranted (level 4). Inflammatory bowel disease (IBD) Miscellaneous Not included Not included
KCE reports vol.45 Screening for Colorectal Cancer: Appendices 185 Nr. Title Issued by Year Familial Adenomatous Polyposis (FAP) & related 12 Preventive health care, 2001 update: colorectal cancer screening 28. Canadian Task Force on Preventive Health Care (CTFPHC) 2001 1. genetic counseling should be performed prior to genetic testing 2. FS beginning at puberty 3. Individuals from families where the gene mutation has been identified but are negative themselves, require screening similar to the average risk population 4. For at risk individuals where the mutation has not been identified in the family or where genetic testing is not available, screening with annual or biennial FS should be undertaken beginning at puberty Hereditary Non-Polyposis Colon Cancer (HNPCC) 1. Based on Level III evidence, the Task Force recommends screening with colonoscopy in individuals from HNPCC kindreds 2. The ages when screening should begin and the frequency at which colonoscopy should be performed are unclear. Personal history of CRC resection Personal history of colonpolyps Inflammatory bowel disease (IBD) Miscellaneous Not included Not included Not included Not included
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KCE reports 1. Effectiviteit en kos
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