Report in English with a Dutch summary (KCE reports 45A)

KCE reports vol.45 Screening for Colorectal Cancer: Appendices 173
7 Adult preventive
health care: cancer
screening 187 .
8 Colorectal cancer
screening and
University of Michigan
Health System (UMHS)
U.S. Multisociety Task Force
on Colorectal Cancer
Category 2 risk:
1 FDR with CRC diagnosed < 55 y or 2
FDR on the same side of the family with
CRC diagnosed at any age
Category 1 risk:
1 FDR with CRC diagnosed 55 y
2004 2 FDR with CRC or 1 FDR with CRC
or adenomatous polyps diagnosed at < 60
y
2003 One FDR with CRC or adenomatous
polyp at age 60 y, or 2 SDR with CRC
Colonoscopy(1). Fully
inform individuals about
their risk of developing
CRC and the reason for
this recommendation (2).
Individuals should be
informed that
colonoscopy is generally
a safe procedure, but it is
an invasive procedure
with some rare but
recognised risks (3).
No specific screening
recommendations are
made for this group at
this time given the slight
increase in risk, the
uncertainty regarding the
age at which this
additional risk is
expressed, and the
concern regarding the
appropriateness of
colonoscopy as a
screening procedure in
this group (1). Prompt
investigation of lower
bowel symptoms is
advised (2). Individuals
requesting information
should be fully informed
regarding their absolute
risk of developing CRC
and advised of the
reasons for this
recommendation (3).
50 y or 10 y
younger than the
earliest diagnosis
in the family,
whichever
comes first
Every 5 y Grade 3
for (1)
Grade 5
for (2) and
(3)
N/A N/A Grade 5
for (1),(2)
& (3)
Colonoscopy 40 y or 10 y
younger than the
earliest diagnosis
in the family,
whichever
comes first
Every 5 y
Average risk screening 40 y N/A
Evidence
discussed
but not
explicitly
rated
N/A