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Report in English with a Dutch summary (KCE reports 45A)

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134 Screen<strong>in</strong>g for Colorectal Cancer: Appendices <strong>KCE</strong> <strong>reports</strong> vol.45<br />

out over the next three years. The deadl<strong>in</strong>e however could not be met, because<br />

it takes about six months to commission the screen<strong>in</strong>g centres. A central<br />

budget has been announced of 18,5 million for 2006/7 and 37 million for<br />

2007/8. However no fund<strong>in</strong>g has been provided yet 555. Uptake, def<strong>in</strong>ed as the<br />

proportion of those <strong>in</strong>vited who returned an adequate kit <strong>in</strong> the first phase of<br />

screen<strong>in</strong>g was 58,5 % <strong>in</strong> the first round (2000-2002) of the pilot and 51,9 %<br />

(127.746 were <strong>in</strong>vited) <strong>in</strong> the second round (february 2003-april 2005) 556.<br />

Uptake of colonoscopy was 80,5 % <strong>in</strong> the first round and 82,8 % <strong>in</strong> the second<br />

round.<br />

In the national program men and women aged 60 to 69 registered <strong>with</strong> the<br />

NHS will be <strong>in</strong>vited to take part <strong>in</strong> FOBT screen<strong>in</strong>g every two years. This age<br />

range is narrower than <strong>in</strong> many other countries because of concerns about the<br />

capacity of the National Health Service to deliver sufficient numbers of<br />

colonoscopies <strong>with</strong>out affect<strong>in</strong>g the symptomatic service 30. People over 70 can<br />

request a screen<strong>in</strong>g kit by call<strong>in</strong>g a freephone helpl<strong>in</strong>e when the program<br />

reaches their area. Five program hubs will operate a national call and recall<br />

system to send out fecal occult blood (guaiac FOBT) test kits, analyse samples<br />

and dispatch results. The population expected to be covered by each<br />

programme hub is 10 million people.<br />

The program hubs will have the follow<strong>in</strong>g functions:<br />

Responsibility for up to 20 screen<strong>in</strong>g centres<br />

Call/recall of population for <strong>in</strong>itial screen<strong>in</strong>g<br />

Assembly and dispatch of kits to <strong>in</strong>vited population<br />

Laboratory test the returned kits<br />

Dispatch of test results to <strong>in</strong>dividuals <strong>with</strong><strong>in</strong> 48 hours of receipt<br />

Book appo<strong>in</strong>tments at specialist screen<strong>in</strong>g nurse cl<strong>in</strong>ics for<br />

people receiv<strong>in</strong>g an abnormal result (nurse positive cl<strong>in</strong>ics) at<br />

local screen<strong>in</strong>g centre <strong>with</strong> result letter <strong>with</strong><strong>in</strong> one week of<br />

result<br />

Provide a help l<strong>in</strong>e<br />

Have overview of screen<strong>in</strong>g centres/cl<strong>in</strong>ic space<br />

Facilitate polyp surveillance for screen<strong>in</strong>g patients<br />

The first screen<strong>in</strong>g centres are situated <strong>in</strong> Wolverhampton, Norwich, Liverpool<br />

and Torbay. By March 2007, all five program hubs and around fourteen local<br />

screen<strong>in</strong>g centres will be established. Screen<strong>in</strong>g centres will be selected based<br />

on a global rat<strong>in</strong>g scale. The parameters are wait<strong>in</strong>g times and patient<br />

experience, adequate number of accredited colonoscopists to provide timely<br />

colonoscopy per year and ability to offer all patients a colonoscopy <strong>with</strong><strong>in</strong> two<br />

weeks of a nurse positive cl<strong>in</strong>ic appo<strong>in</strong>tment. In order to achieve a high level of<br />

quality control, a system of accreditation will be <strong>in</strong>troduced 557. Screen<strong>in</strong>g<br />

centres will l<strong>in</strong>k not only to the program hub but also to local hospitals and<br />

cancer centres where the plann<strong>in</strong>g will take place for associated treatments<br />

such as pathology, surgery, further imag<strong>in</strong>g, oncology and palliative care.<br />

Competence and performance of colonoscopists will be evaluated by<br />

submission to a regular audit of practice that will <strong>in</strong>clude observation of two<br />

colonoscopies by tri-split video. Quality <strong>in</strong>dicators are: a completion rate <strong>with</strong><br />

photographic evidence of ileo caecal valve > 90 %, an adenoma detection rate of<br />

at least 35 %, complete polyp resection of over 90 % of those excised, correct

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