Report in English with a Dutch summary (KCE reports 45A)
Report in English with a Dutch summary (KCE reports 45A)
Report in English with a Dutch summary (KCE reports 45A)
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132 Screen<strong>in</strong>g for Colorectal Cancer: Appendices <strong>KCE</strong> <strong>reports</strong> vol.45<br />
designed accord<strong>in</strong>g to the EU recommendations and focused on asymptomatic<br />
<strong>in</strong>dividuals aged over 50, <strong>with</strong> first FOBT, provided and <strong>in</strong>terpreted by GP s, and<br />
if positive patients are referred for colonoscopy performed by a<br />
gastroenterologist. The expenses are covered by health <strong>in</strong>surance 544.<br />
After 4 years the global data show that about 20% of the targeted population<br />
participates <strong>in</strong> the program. 97% of GPs <strong>in</strong> the country jo<strong>in</strong>ed the program and<br />
20 % of them reached 50% FOBT coverage of targeted population. The data<br />
from practices show that 80-90 % of patients return the test <strong>with</strong><strong>in</strong> three<br />
months. However, 10-20 % refuse colonoscopy when FOBT was positive.<br />
7.6.2 Groups at <strong>in</strong>creased or high risk<br />
7.7 FRANCE<br />
People at high risk of hav<strong>in</strong>g colorectal cancer are recruited by GPs or<br />
gastroenterologists for an early colonoscopy or FOBT test<strong>in</strong>g at age of 40 and<br />
further on a yearly basis although the approach can vary <strong>in</strong>dividually.<br />
7.7.1 Average risk groups<br />
In 1998, the Agence nationale d accréditation et d évaluation en santé<br />
(ANAES) recommended <strong>in</strong> a consensus conference the <strong>in</strong>troduction of an<br />
organised screen<strong>in</strong>g program for <strong>in</strong>dividuals between 50 and 74 years by means<br />
of a FOBT test every two years 545. In 2002, 22 departments (out of 95) have<br />
been selected for a pilot project. Follow<strong>in</strong>g the positive experience <strong>in</strong> those<br />
departments, colorectal cancer screen<strong>in</strong>g <strong>with</strong> FOBT was extended to 50<br />
departments <strong>in</strong> 2005 and is planned to be nationally implemented by 2007.<br />
Between 2002 and 2004, 2.700.000 persons were <strong>in</strong>vited and 716.000<br />
participated (+/ 26%) 546. The average participation rate <strong>in</strong> departments <strong>with</strong> an<br />
activity of more than 1 year and hav<strong>in</strong>g <strong>in</strong>vited more that 80 % of the population<br />
of the department was 33 %. It also appeared that the participation rate<br />
<strong>in</strong>creases <strong>with</strong> the duration of the program. In the department Haut Rh<strong>in</strong> a<br />
participation rate of 53,13 % (2006) was reached 547.<br />
A coupled strategy is used 548. First, <strong>in</strong>vitation letters are sent to <strong>in</strong>dividuals from<br />
the target group by a central adm<strong>in</strong>istration, the structure de gestion<br />
départemental 549. An <strong>in</strong>formation leaflet and a brief questionnaire are <strong>in</strong>cluded<br />
to the <strong>in</strong>vitation letter <strong>in</strong> order to identify the persons that have to be excluded<br />
from the screen<strong>in</strong>g program. Furthermore a self-adhesive label <strong>with</strong> the<br />
identification data is sent to the <strong>in</strong>dividual. The <strong>in</strong>dividual has to get the test<br />
from the GP, who has to expla<strong>in</strong> the objectives of the test to allow the patient<br />
to grasp its use and the consequences <strong>in</strong> case of a positive test result. The test<br />
will be realised at the <strong>in</strong>dividual s home. Afterwards <strong>in</strong>dividuals have to send the<br />
test to a central laboratory for analysis 550 (centre de lecture). These<br />
laboratories send the test results to the central adm<strong>in</strong>istration. The central<br />
adm<strong>in</strong>istration forwards the results to the patient and the GP. Those <strong>with</strong> a<br />
positive test result are recommended to undergo a colonoscopy. Individuals<br />
who underwent a colonoscopy are excluded from screen<strong>in</strong>g for the next 5<br />
years.<br />
If persons did not get tested after the first <strong>in</strong>vitation letter, a rem<strong>in</strong>der <strong>with</strong> a<br />
test is sent by mail by the central adm<strong>in</strong>istration to those <strong>in</strong>dividuals from the<br />
eligible target population that did not explicitly refuse to undergo the test. The<br />
GP has to <strong>in</strong>dicate the persons that are not eligible to get screened or the<br />
persons that refused the test to the central adm<strong>in</strong>istration. GP s are paid a fixed