Non-specific neck pain: diagnosis and treatment - KCE

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36 Non-Specific Neck Pain: diagnosis and treatment KCE Reports 119 SEARCH STRATEGY PUBMED SECOND SEARCH Author Name Giannoula Tsakitzidis Project number PPF08-24-GCP Project name Cervicalgia : Diagnosis and Therapy Keywords Neck Pain Date 14-05-2009 Database Pubmed (name + access ; eg Medline OVID) Search Strategy (attention, for PubMed, check « Details ») Neck Pain Clinical queries+diagnosis+narrow: Search (Neck Pain[Mesh] AND (specificity[Title/Abstract]) Limits: published in the last 10 years, Humans, English, French, German, Dutch, all Adult: 19+years n= 29 Search (neck pain AND (specificity[Title/Abstract]) Limits: published in the last 10 years, Humans, English, French, German, Dutch, all Adult: 19+years n= 45 Note Only the narrow search will be included because of the big range and a lot of bias. Many articles are not relevant for the study. SEARCH STRATEGY EMBASE Author Name Tsakitzidis Giannoula Project number PPF08-24-GCP Project name Cervicalgia : Diagnosis and Therapy Keywords Neck pain, ‘neck pain’ [Mesh], diagnosis, specificity Date 16-06-2009 Database Embase (name + access ; eg Medline OVID) Search Strategy (attention, for PubMed, check « Details ») Note #1. 'neck pain'/exp/dm_di AND ([dutch]/lim OR [english]/lim OR [french]/lim OR [german]/lim) AND [embase ]/lim n= 474 #2. 'neck pain'/exp/dm_di/mj AND ([dutch]/lim OR [english]/lim OR [french]/lim OR german]/lim) AND [embase]/lim AND [humans]/lim AND [embase]/lim AND [1998-2009]/py n= 205 #3. specificity:ti,ab AND [1998-2009]/py N= 131,416 #4. 'neck pain'/exp AND [1998-2009]/py 5,520 16 Jun 2009 #5. #3 AND #4 n= 55 #6. ('neck'/exp OR 'neck') AND ('pain'/exp OR 'pain') AND [1998-2009]/py N= 14,069 #7. #3 AND #6 n= 127 #8. #3 AND #4 AND ([dutch]/lim OR [english]/lim OR [french]/lim OR [german]/lim) AND [embase]/lim N= 49 #9. #3 AND #6 AND ([dutch]/lim OR english]/lim OR [french]/lim OR [german]/lim) AND [humans]/lim AND [embase]/lim N= 101
KCE Reports 119 Non-Specific Neck Pain: diagnosis and treatment 37 APPENDIX 2: CRITERIA USED TO ASSESS THE METHODOLOGICAL QUALITY OF THE STUDIES: RESULTS OF THE QUALITY APPRAISAL QUALITY APPRAISAL: PAPERS ON DIAGNOSIS Author (y) Questions (Quadas for diagnosis instrument) TOTAL Medium/High /14 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Björkstén, 1999 1 1 1 1 0 1 1 1 1 1 1 1 0 1 12 H De Hertogh, 2007 1 1 1 1 0 0 1 1 1 1 1 1 0 0 10 H Vos, 2009 1 1 1 0 1 1 1 1 1 1 1 0 0 0 10 H For all questions 1=yes Questions: 1. Was the spectrum of patients representative of the patients who will receive the test in practice? 2. Were selection criteria clearly described? 3. Is the reference standard likely to correctly classify the target condition? 4. Is the time period between reference standard and index test short enough to be reasonably sure that the target condition did not change between the two tests? 5. Did the whole sample or a random selection of the sample, receive verification using a reference standard of diagnosis? 6. Did patients receive the same reference standard regardless of the index test result? 7. Was the reference standard independent of the index test (i.e. the index test did not form part of the reference standard)? 8. Was the execution of the index test described in sufficient detail to permit replication of the test? 9. Was the execution of the reference standard described in sufficient detail to permit its replication? 10. Were the index results interpreted without knowledge of the results of the reference standard? 11. Were the reference standard results interpreted without knowledge of the results of the index test? 12. Were the same clinical data available when test results were interpreted as would be available when the test is used in practice? 13. Were uninterpretable/intermediate test results reported? 14. Were withdrawals from the study explained? Note: Publications with a score < 7 were excluded. Author (y) Questions (Dutch Cochrane for diagnosis instrument) Total/7 Medium/High 1 2 3 4 5 6 7 Rubinstein, 2007 1 1 1 1 1 1 1 7 H Rubinstein, 2008 1 1 1 1 0 0 0 4 M Sehgal, 2007 1 1 1 1 1 1 0 6 H For all questions 1=yes Questions: 1. Is the question adequately formulated? 2. Is search strategy adequately performed? 3. Is the selection procedure of the publications adequately performed? 4. Is the quality appraisal adequately performed? 5. Is the description of the data-extraction adequately performed? 6. Is the description of the study baseline characteristics adequate? 7. Is the meta-analysis correctly performed? Note: Publications with a score < 4 were excluded.
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