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Non-specific neck pain: diagnosis and treatment - KCE

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<strong>KCE</strong> Reports 119 <strong>Non</strong>-Specific Neck Pain: <strong>diagnosis</strong> <strong>and</strong> <strong>treatment</strong> 11<br />

Figure 2: Flow chart: final results of the second search for <strong>diagnosis</strong> <strong>and</strong><br />

prognosis<br />

2.3 DATA EXTRACTION<br />

Based on the selection described above, two researchers independently extracted the<br />

data of the included systematic reviews using prepiloted forms. Data were reported in<br />

an evidence table (appendix 2) containing four main themes ‘Diagnosis’, ‘Assessment of<br />

<strong>pain</strong> <strong>and</strong> disability’, ‘Prognosis’ <strong>and</strong> ‘Treatment’. For the screening of the RCT’s <strong>and</strong> the<br />

publications on <strong>diagnosis</strong> <strong>and</strong> prognosis on full text, one researcher extracted the data<br />

of the included publications (respectively see appendix 3 <strong>and</strong> appendix 4). Data from the<br />

selected guidelines were extracted by one researcher. Finally, the results from these<br />

selected guidelines have been compared to the conclusions from the literature search<br />

by two researchers.<br />

The results of the data extractions are reported in appendix 5 <strong>and</strong> chapter 3.4.<br />

The results from the literature are defined per main theme <strong>and</strong> subtheme in the<br />

following paragraphs <strong>and</strong> where possible the level of evidence in “Grade” is given, 20, 21 .<br />

• “Grade A”, highest level of evidence: RCTs without important limitations<br />

or overwhelming evidence from observational studies;<br />

• “Grade B”, moderate level of evidence: RCTs with important limitations<br />

(inconsistent results, methodological flaws, indirect, or imprecise) or<br />

exceptionally strong evidence from observational studies;<br />

• “Grade C”, lowest level of evidence: studies with lower level of evidence<br />

than above.

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