Lab Safety Manual - UCLA - Environment, Health & Safety

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esponse. This information is intended to be a resource and to help laboratory personnel minimize hazards. In view of the wide variety of chemical products handled in laboratories, it should not be assumed that the precautions and requirements stated in this manual are all-inclusive. Faculty, researchers and students are expected to learn about the hazards of chemical products before handling them. Principal Investigators (PIs) and Laboratory Supervisors should include supplemental information pertinent to their specific areas in this manual. Laboratory operations that utilize radioactive materials or radiation producing machines, biological hazards, laser operations, or shop activities must to follow additional guidelines outlined in hazard-specific UCLA manuals (e.g., Biosafety Manual, Radiation Safety Manual, Laser Safety Manual, etc.). 1. Injury and Illness Prevention Plan The development and implementation of laboratory specific Injury and Illness Prevention Plan is a key step in strengthening the safety culture in laboratories. The UCLA Injury and Illness Prevention Plan (IIPP) is a guide that is available to assist PIs/Laboratory Supervisors to develop laboratory specific safety programs for employees. Mandated by California law, an IIPP provides a framework for laboratories to provide their employees with equipment and information necessary to work safely within their specific work environments. It assigns responsibility for safety to specific individuals and outlines procedures to assure compliance with safety procedures. This safety program must address identification, communication, and correction of hazards, as well as accident investigations, training and recordkeeping. A well-integrated IIPP provides the information required to monitor activities and resources to reduce the risk of workplace injury and illness to maintain a safe work environment. Title 8, of the California Code of Regulations (CCR), requires every California employer to have an effective written IIPP in accord with CCR Section 3203 of the General Industry Safety Orders. The Laboratory Safety Manual includes a brief section providing the purpose and components of the IIPP. Procedures related to “assignment of responsibilities,” “hazard identification,” “hazard mitigation,” “incident reporting,” and “training” are included in the various sections of the Laboratory Safety Manual. 2. Chemical Hygiene Plan The Chemical Hygiene Plan (CHP) establishes a formal written program for protecting laboratory personnel against adverse health and safety hazards associated with exposure to potentially hazardous chemicals and must be made available to all employees working with hazardous chemicals as required in Title 8, California Code of Regulations (CCR), Section 5191 (Occupational Exposures to Hazardous Chemicals in Laboratories). The CHP describes the proper use, handling practices and procedures to be followed by faculty, staff, students, visiting scholars, and all other personnel working with potentially hazardous chemicals in laboratory settings. UCLA Laboratory Safety Manual 2 December 201
3. Laboratory Specific Standard Operating Procedures Standard Operating Procedures (SOPs) are written instructions that detail the steps that will be performed during a given experimental procedure and include information about potential hazards and how these hazards will be mitigated. SOPs should be written by laboratory personnel who are most knowledgeable and involved with the experimental process. The development and implementation of SOPs is a core component of promoting a strong safety culture in the laboratory and helps ensure a safe work environment. PIs/Laboratory Supervisors are required to develop and implement laboratory-specific SOPs for certain hazardous chemicals and “particularly hazardous substances” (PHS) that are used in their laboratories. These SOPs must be submitted and reviewed by the Department Safety Committee prior to implementation. For certain hazardous chemicals, PHS, or specialized practices, consideration must be given to whether additional consultation with safety professionals is warranted or required. Circumstances requiring prior approval from the PI/Laboratory Supervisor must also be addressed in laboratory-specific SOPs. The Chemical Hygiene Plan (see Chapter 4 and Appendix D) provides more detailed information on SOPs. SOPs should be kept in the Laboratory Safety Manual under the appropriate tab. 4. Safety Training Records Effective training is a critical component to facilitating a safe environment and for the prevention of laboratory accidents. All employees must be trained in general safe work practices and be given specific instructions on hazards unique to their job assignment. Meeting safety training requirements is a cooperative effort between departments, Principal Investigators and Laboratory Supervisors, laboratory staff and EH&S. An effective health and safety training program must include appropriate oversight, proper recordkeeping, instruction on the proper use of PPE (e.g., eye protection, gloves, laboratory coats, respirators, etc.), and extensive outreach. Accurate recordkeeping of training activities demonstrates a commitment to the safety and health of the UCLA community, integrity of research and protection of the environment. EH&S is responsible for maintaining records of training conducted by EH&S staff members. Departments or laboratories are required to document and maintain record of all health and safety training, including safety meetings, one-on-one training, and classroom and online training. Safety training records should be kept in the Laboratory Safety Manual under the appropriate tab, including records of EH&S conducted sessions. 5. Laboratory Inspection Records EH&S has instituted a laboratory inspection program for all laboratories in the science, engineering and technology areas. Laboratories are currently inspected on an annual basis by EH&S Safety Specialists to ensure compliance with federal, state and university requirements. Most of the standards are contained in Title 8 of the California Code of Regulations (CCR), General Industry Safety Orders (including sections 3380- 3385 on Personal Protective Devices), Title 19, State Fire Marshal, and in Title 40 of the Environmental Protection Agency, Code of Federal Regulations. EH&S Safety Specialists conduct inspections, issue reports, conduct re-inspections when deficiencies UCLA Laboratory Safety Manual 3 December 201
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Page 6 and 7: are noted, and provide training and
Page 8 and 9: IIPP
Page 10 and 11: Chemical Hygiene Plan January 2013
Page 12 and 13: Table of Contents Chapter 1: Introd
Page 14 and 15: Chapter 1: Introduction Purpose UCL
Page 16 and 17: All personnel, including PIs/Labora
Page 18 and 19: c. Preparing SOPs and performing li
Page 20 and 21: Chapter 2: Chemical Hazard Communic
Page 22 and 23: EMPLOYEE INFORMATION AND TRAINING E
Page 24 and 25: Chapter 3: Classes of Hazardous Che
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Page 28 and 29: Acute Toxins Substances that have a
Page 30 and 31: nanomaterials are used as fine powd
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Page 40 and 41: An annual refresher is required for
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flammable solvent. Other common haz
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fuel-gas cylinders securely in the
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Chapter 7: Training Regulatory Requ
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Resources EH&S has a number of tool
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Chapter 8: Inspections and Complian
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and safety training, including safe
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Chapter 9: Hazardous Chemical Waste
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The manufacturer‟s SDS provides d
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Peroxide Forming Chemicals Peroxide
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appropriate lab coat, gloves and ey
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BENCH TOP TREATMENT EPA regulations
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Chapter 10: Accidents and Chemical
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Chemical Spills Chemical spills can
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Appendices Chemical Hygiene Plan Ja
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Appendix A: General Rules for Labor
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UNSAFE LABORATORY HABITS Personal P
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Appendix B: Sample Safety Data Shee
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Sample SDS, cont. Obtain SDS from t
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Appendix C: Container Labeling Chem
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Appendix D: SOP Instructions and Te
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Sample SOP Template Obtain this for
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Sample SOP Template, cont. Obtain t
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Sample SOP Template, cont. Obtain t
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Appendix E: UCLA Particularly Hazar
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substances or generalized over a gr
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E. Engineering Controls 1. Bench to
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educe exposure. If levels cannot be
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4. It is listed in either Group 2A
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A T T A C H M E N T C Listed Carcin
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Appendix F: Regulated Carcinogens C
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Appendix G: Respiratory Hazard Asse
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Appendix H: Peroxide Forming Chemic
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Appendix I: EH&S Safety Training Ma
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Appendix J: Employee Training Histo
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Appendix K: Site-Specific Training
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Appendix L: Laboratory Inspection C
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Laboratory Inspection Checklist, co
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Appendix M: Segregation of Incompat
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Appendix N: Hazardous Waste Pick-Up
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Appendix O: Spill Clean-up Procedur
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Appendix P: Lab Emergency Poster Ob
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Appendix Q: Policy 905 - Research L
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B. Protective gloves must be worn w
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Appendix R: NanoTool Kit Chemical H
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Chemical Hygiene Plan R-3 January 2
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Chemical Hygiene Plan R-11 January
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Appendix S: Facilities Service Cons
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Appendix T: PPE Issuance Form Chemi
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Appendix U: Glossary ACGIH - The Am
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GENERAL VENTILATION - Also known as
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MUTAGEN - Anything that can cause a
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Lab Specific SOPs
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Inspection Records
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Resources
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3. Outline Lab Safety Training Requ
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Lab Safety Manual - UCLA - Environment, Health & Safety

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