The 2NN study - CD8 T cells

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Participating countries<br />

17 countries 65 centers<br />

Frank van Leth 2

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Participating countries 17 countries 65 centers Frank van Leth 2

NVP 400 mg od n=220 Trial design 1216 ART naive patients NVP 200 mg bd n=387 EFV 600 mg od n=400 Nucleoside backbone: d4T and 3TC Inclusion criteria: pVL > 5000 copies/mL any CD4 cell count any stage of CDC-classification NVP+ EFV 400 / 800mg od n=209 Frank van Leth 3

Page 1: The 2NN study A randomised comparat
Page 5 and 6: Methods • All analyses Intention-
Page 7 and 8: Baseline characteristics NVP-od NVP
Page 9 and 10: % patie nts with virologic success
Page 11 and 12: percentage of patients 100 75 50 25
Page 13 and 14: number of CD4+ -cells (median (IQR)
Page 15 and 16: Grade 3 or 4 laboratory toxicities
Page 17 and 18: plasma HDL mmol/L 1.50 1.25 1.00 0.
Page 19 and 20: Conclusions • NVP and EFV have co
Page 21 and 22: Acknowledgements (2) Other investig

The 2NN study - CD8 T cells

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