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Curriculum Vitae Michalis (Michael) V. Karamouzis - MyLoyalCard

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Name: <strong>Michalis</strong> (<strong>Michael</strong>) <strong>Karamouzis</strong><br />

Date of Birth: 31.01.1972<br />

Nationality: Greek<br />

<strong>Curriculum</strong> <strong>Vitae</strong><br />

<strong>Michalis</strong> (<strong>Michael</strong>) V. <strong>Karamouzis</strong><br />

Mail Address: Marasli 3, 10676 Kolonaki, Athens, Greece<br />

Tel: +302130158287<br />

Mobile: +306944290909<br />

Fax: +302130158287<br />

E-Mail: karam@otenet.gr<br />

Present Working Position: Assistant Professor, Medical School, University of<br />

Athens, Athens, Greece<br />

Under-graduate Studies: School of Medicine, University of Patras, Patras, Greece<br />

(1990-1995).<br />

Post-graduate Studies:<br />

(1) Master of Science in Pharmacokinetics and Toxicology in School of Medicine,<br />

University of Patras, Patras, Greece.<br />

(2) PhD in School of Medicine, University of Patras, Patras, Greece – Thesis: “Cross-<br />

talk of retinoid receptors and the transcription factor AP-1 in laryngeal<br />

carcinogenesis and possible applications in chemoprevention”.<br />

Previous working positions:<br />

1) Fellow of Internal Medicine, Department of Internal Medicine, 251 Hospital of<br />

Greek Air Force, Athens, Greece (4\9\98-4\7\99).<br />

2) Fellow of Internal Medicine, Department of Internal Medicine, University<br />

Hospital of Patras, Patras, Greece (12\7\99-25\3\01).<br />

3) Fellow of Hematology-Oncology, Division of Hematology-Onvology, Department<br />

of Medicine, University Hospital of Patras, Patras, Greece (29\6\01-15\1\02).<br />

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4) Fellow of Medical Oncology, St. Savvas Anticancer-Oncological Hospital,<br />

Athens, Greece (24/3/2003-24/3/2006).<br />

5) Visiting Assistant Professor, Division of Hematology-Oncology, Department of<br />

Medicine, University of Pittsburgh, USA (01/09/2006-31/08/2007).<br />

Publications in peer-reviewed journals<br />

1) S. Andrikopoulos, M. <strong>Karamouzis</strong>, G. Papachristou, A. Vagenakis & H<br />

Kalofonos: "The status of undergraduate oncology education in Medical Schools<br />

in Greece and abroad", J Cancer Educ, 14(4): 223-227, 1999.<br />

2) H.P. Kalofonos, M.V. <strong>Karamouzis</strong> & A.A. Epenetos: "Radioimmunoscintigraphy<br />

in patients with ovarian cancer", Acta Oncol, 40(5): 549-557, 2001.<br />

3) S. Voulgaris, M. Partheni, M. <strong>Karamouzis</strong>, P. Dimopoulos, N. Papadakis & H.P.<br />

Kalofonos: "Intratumoral doxorubicin in patients with malignant brain gliomas",<br />

Am J Clin Oncol, 25(1): 60-64, 2002.<br />

4) A.G. Papatsoris, F.A. Mpadra & M.V. <strong>Karamouzis</strong>: "Prostatic adenocarcinoma<br />

presenting as solitary cerebellar metastasis. Case report and review of the<br />

literature", Tumori, 88(1): 61-64, 2002.<br />

5) M.V. <strong>Karamouzis</strong>, T. Papadas, I. Varakis, G. Sotiropoulou-Bonikou & A.G.<br />

Papavassiliou: "Induction of the CBP transcriptional co-activator early during<br />

laryngeal carcinogenesis", J Cancer Res Clin Oncol, 128(3): 135-140, 2002.<br />

6) T. Papadas, N. Charokopos, M.V. <strong>Karamouzis</strong>, C. Pierakeas, M. Symeonidi, G.<br />

Economou & P. Goumas: "Rehabilitation after laryngectomy - A practical<br />

approach and guidelines", J Cancer Educ, 17(1): 37-39, 2002.<br />

7) M.V. <strong>Karamouzis</strong>, VG Gorgoulis, A.G. Papavassiliou: "Transcription factors and<br />

neoplasia: vistas in novel drug design", Clin Cancer Res, 8(6): 949-961, 2002.<br />

8) M.V. <strong>Karamouzis</strong>, E. Likaki-Karatza, F.A. Mpadra, P. Ravazoula, D. Koukouras,<br />

E. Tzorakoeleptherakis, A.G. Papavassiliou & H.P. Kalofonos: "Non-palpable<br />

breast carcinomas: correlation of mammographically detected malignant-<br />

appearing microcalcifications and molecular prognostic factors", Int J Cancer,<br />

102(1): 86-90, 2002.<br />

9) E. Likaki-Karatza, F.A. Mpadra, M.V. <strong>Karamouzis</strong>, P. Ravazoula, D. Koukouras,<br />

S. Margariti & I. Dimopoulos: "Acute lymphoblastic leukemia (ALL) relapse in<br />

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east diagnosed with gray-level and color doppler ultrasonography", J Clin Ultr,<br />

30(9): 552-556, 2002.<br />

10) A.G. Papatsoris, F.A. Mpadra, M.V. <strong>Karamouzis</strong> & C.Y. Frangides: "Bruccelar<br />

orcheoepididimytis in Western Greece: ten years experience", Int J Infect Dis,<br />

6(4): 309-313, 2002.<br />

11) A.G. Papatsoris, F.A. Badra & M.V. <strong>Karamouzis</strong>: "Post-traumatic testicular<br />

torsion". Ulus Trauma Derg, 9(1): 70-71, 2003.<br />

12) E.G. Solomou, G. Patriarheas, F.A. Mpadra, M.V. <strong>Karamouzis</strong> & I. Dimopoulos:<br />

"Asymptomatic adult cystic lymphangioma of the spleen: Case report and review<br />

of the literature". Magn Reson Imaging, 21: 81-84, 2003.<br />

13) A.G. Papatsoris, F.A. Badra, M.V. <strong>Karamouzis</strong>, E. Likaki-Karatza & T. Karatzas:<br />

"Torsion of undescended testis in an adult with Down's syndrome". Int J Urology,<br />

10: 233-235, 2003.<br />

14) M.V. <strong>Karamouzis</strong>, M. Melachrinou, M. Fratzoglou, Ch Labropoulou-Karatza &<br />

H.P. Kalofonos: "Hepatocellular carcinoma metastasis in the pituitary gland: case<br />

report and review of the literature", J Neuro-Oncology, 63(2): 173-177, 2003.<br />

15) M.V. <strong>Karamouzis</strong>, F.A. Badra & A.G. Papatsoris: "A case of colonic ischemia<br />

mimicking carcinoma". Int J Gastrointestinal Cancer, 32(2-3): 165-168, 2003.<br />

16) M.V. <strong>Karamouzis</strong>, G. Sotiropoulou-Bonikou, G. Vandoros, I. Varakis & A.G.<br />

Papavassiliou: “Retinoid-X-receptor alpha (RXRα) expression during laryngeal<br />

carcinogenesis: Detrimental or beneficial event?”. Cancer Lett, 199(2): 175-183,<br />

2003.<br />

17) Α. Alexopoulos, D. Tryfonopoulos, M.V. <strong>Karamouzis</strong>, G. Gerasimidis, I. Karydas,<br />

K. Kandilis, J. Stavrakakis, H. Stavrinides, C. Georganta, A. Ardavanis & G.<br />

Rigatos: “Evidence for In Vivo Synergism between Docetaxel and Gemcitabine in<br />

Patients with Metastatic Breast Cancer”. Ann Oncol, 15: 88-94, 2004.<br />

18) M.V. <strong>Karamouzis</strong>, G. Sotiropoulou-Bonikou, G. Vandoros, I. Varakis & A.G.<br />

Papavassiliou: “Differential expression of retinoic acid receptor beta (RARβ) and<br />

AP-1 transcription factor in normal, premalignant and malignant human laryngeal<br />

tissues”. Eur J Cancer, 40: 761-773, 2004.<br />

19) M.V <strong>Karamouzis</strong> & A.G. Papavassiliou: “COX-2 inhibition in cancer<br />

therapeutics: a field of controversy or a magic bullet?”. Expert Opin Invest Drugs,<br />

13: 359-372, 2004.<br />

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20) Α. Alexopoulos, M.V. <strong>Karamouzis</strong>, H. Stavrinides, A. Ardavanis, K. Kandilis,<br />

J. Stavrakakis, C. Georganta & G. Rigatos: “Phase II study of pegylated liposomal<br />

doxorubicin (Caelyx ® ) and docetaxel as first line treatment in metastatic breast<br />

cancer” Ann Oncol, 15: 891-895, 2004.<br />

21) H.P. Kalofonos, D. Bafaloukos, T.G. Kourelis, M.V. <strong>Karamouzis</strong>, P. Megas, G.<br />

Iconomou, D. Dimitropoulos, P. Kosmidis & E. Lampiris: "Adriamycin and cis-<br />

platinum as first line treatment in unresectable locally advanced or metastatic adult<br />

soft tissue sarcomas". Am J Clin Oncol, 27: 307-311, 2004.<br />

22) Α. Alexopoulos, M.V. <strong>Karamouzis</strong> & G. Rigatos: “In Vivo Synergism<br />

between Docetaxel and Gemcitabine in Patients with Metastatic Breast Cancer:<br />

The general concept and the future perspectives of such a rationale approach”,<br />

Semin Oncol, 31 (suppl 5): 25-30, 2004.<br />

23) A.G. Papatsoris, A. Triantafyllidis, A. Gekas, M.V. <strong>Karamouzis</strong> & T. Rosenbaum:<br />

“Leydig cell tumor of the testis. New cases and review of the current literature”.<br />

Tumori, 90: 422-423, 2004.<br />

24) M.V. <strong>Karamouzis</strong>, N. Apostolikas, Ch. Georganta, G. Lainakis, K. Kandylis & G.<br />

Rigatos: “A case of relapsed CD20 (+) mixed cellularity Hodgkin‟s Disease<br />

treated with sequential Rituximab and Radiotherapy” Am J Haematol, 77: 418-<br />

419, 2004.<br />

25) F.A. Badra, M.V. <strong>Karamouzis</strong>, V. Zolota & V. Pastromas: “A case of multi-organ<br />

Langerhan‟s cell histiocytosis presented with pneumothorax”, Eur J Intern Med,<br />

15: 467-469, 2004.<br />

26) M.V. <strong>Karamouzis</strong>: “The status of chemoprevention in the current cancer<br />

therapeutic armamentarium”, Journal of BUON, 9: 363-372, 2004.<br />

27) H.P. Kalofonos, C. Kourousis, M.V. <strong>Karamouzis</strong>, G. Iconomou, P. Megas & V.<br />

Georgoulias: “A phase II study of docetaxel and epirubicin in advanced adult soft<br />

tissue sarcomas”, Sarcoma, 4: 129-133, 2004.<br />

28) M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Retinoid receptors cross talk in<br />

respiratory epithelium cancer chemoprevention”, Trends in Molecular Medicine,<br />

11: 10-16, 2005.<br />

29) A.G. Papatsoris, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Novel insights into the<br />

implication of the IGF-1 network in prostate cancer”, Trends in Molecular<br />

Medicine, 11: 52-55, 2005.<br />

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30) Α.G. Papatsoris, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Novel biological<br />

agents for the treatment of hormone-refractory prostate cancer”, Curr Med Chem,<br />

12(3): 277-296, 2005.<br />

31) M.V. <strong>Karamouzis</strong>, A. Ardavanis, A. Alexopoulos, A. Papadopoulou, N.<br />

Apostolikas & G. Rigatos: “Multiple cutaneous acral metastases in a female with<br />

breast adenocarcinoma treated with pegylated liposomal doxorubicin: Incidental or<br />

etiological association?”, Eur J Cancer Care, 14: 267-271, 2005.<br />

32) A. Ardavanis, D. Tryfonopoulos, G. Orfanos, M. <strong>Karamouzis</strong>, A. Scorilas, A.<br />

Alexopoulos & G. Rigatos: “Safety and Efficacy of Trastuzumab Every 3 Weeks<br />

Combined with Cytotoxic Chemotherapy in Patients with HER2-Positive<br />

Recurrent Breast Cancer: Findings from a Case Series”. Onkologie, 28(11):558-<br />

564, 2005.<br />

33) A. Ardavanis, D. Tryfonopoulos, G. Orphanos, G. Ioannidis, M. <strong>Karamouzis</strong> & G.<br />

Rigatos: “First-line chemotherapy with fluorouracil-epirubicin-navelbine (FEN)<br />

combination in advanced breast cancer”. Anticancer Res, 25: 4493-4498, 2005.<br />

34) A. Ardavanis, M.V. <strong>Karamouzis</strong>, A. Alexopoulos & G. Rigatos: “Simultaneous<br />

endometrioid ovarian and uterine carcinoma diagnosed after in-vitro fertilization<br />

procedure – case report and review of the literature”, Eur J Gynaecol Oncol, 26:<br />

654-656, 2005.<br />

35) G. Vandoros, P.A. Konstantinopoulos, G. Sotiropoulou-Bonikou, A. Kominea, P.<br />

Andrikopoulos, G.I. Papachristou, M.V. <strong>Karamouzis</strong>, M. Gkermpesi, I. Varakis, &<br />

A.G. Papavassiliou: “PPAR-gamma is expressed and NF-KB pathway is activated<br />

and correlates positively with COX-2 expression in stromal myofibroblasts<br />

surrounding colon adenocarcinomas. J Cancer Res Clin Oncol, 132: 76-84, 2006.<br />

36) F.A Badra, M.V. <strong>Karamouzis</strong>, E. Likaki-Karatza, P. Ravazoula, E.<br />

Tzorakoelepftherakis, D. Koukouras, G. Iconomou, D. Siablis, A.G. Papavassiliou<br />

& H.P. Kalofonos: “Non-palpable breast carcinomas: correlation of<br />

mammographically detected malignant-appearing microcalcifications and<br />

epidermal growth factor receptor (EGFR) family expression, Cancer Lett, 244: 34-<br />

41, 2006.<br />

37) Μ.V. <strong>Karamouzis</strong>, A.A. Ifanti, G. Iconomou, A.G. Vagenakis & H.P. Kalofonos:<br />

“Medical students‟ views of undergraduate oncology education: A comparative<br />

study”, Educ Health (Abingdon), 19: 61-70, 2006.<br />

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38) M.V. <strong>Karamouzis</strong>, P. Liodantonaki & G. Rigatos: “A case of breast carcinoma late<br />

metastasis to the kidney”, Am J Clin Oncol, 29:209-210, 2006.<br />

39) A. Ardavanis, A. Scorilas, D. Tryfonopoulos, G. Orphanos, I. Missitzis, M.V.<br />

<strong>Karamouzis</strong>, M. Chrysochoou, A. Sotiropoulou, N. Arnogiannaki, G. Ioannidis, G.<br />

Pissakas, G. Rigatos: “Multidisciplinary Therapy of Locally Far-Advanced or<br />

Inflammatory Breast Cancer with Fixed Perioperative Sequence of Epirubicin,<br />

Navelbine, and Fluorouracil Chemotherapy, Surgery, and Radiotherapy: Long-<br />

Term Results”, The Oncologist, 11: 563-573, 2006.<br />

40) M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “The IGF-1 network in lung carcinoma<br />

therapeutics”, Trends Mol Med, 12:595-602, 2006.<br />

41) M.V. <strong>Karamouzis</strong>, A. Fida, N. Apostolikas & G. Rigatos: “A case of HER-2 (+)<br />

squamous cell breast carcinoma: an unusual presentation of an unusual clinical<br />

entity”, Eur J Surg Oncol, 32:1250-1251, 2006.<br />

42) E.G. Iliopoulou, M.V. <strong>Karamouzis</strong>, I. Missitzis, A. Ardavanis, C.N. Baxebanis, G.<br />

Rigatos, M. Papamichail, S.A. Perez: “Increased frequency of CD4+ cells<br />

expressing CD161 in cancer patients”, Clin Cancer Res, 12: 6901-6909, 2006.<br />

43) M.V. <strong>Karamouzis</strong>, H. Linardou, G. Papadopoulos, E. Bousboukea, D. Kanaloupiti,<br />

M. Bitza, N. Spourlis & D. Bafaloukos: “Gastrointestinal solitary metastases from<br />

lung squamous cell carcinoma”, Lung Cancer, 55: 251-252, 2007.<br />

44) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “The AP-1<br />

Transcription Factor in Respiratory Epithelium Carcinogenesis”, Mol Cancer Res,<br />

5: 109-120, 2007.<br />

45) A.G. Papatsoris, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “The power and<br />

promise of "rewiring" the mitogen-activated protein kinase network in prostate<br />

cancer therapeutics”, Mol Cancer Ther, 6: 811-819, 2007.<br />

46) P.A. Konstantinopoulos, R.J. Sullivan, M.V. <strong>Karamouzis</strong>, & B.J. Dezube:<br />

“Investigational agents for treatment of AIDS-Related Kaposi Sarcoma”, Expert<br />

Opin Investig Drugs, 16: 495-504, 2007.<br />

47) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “Roles of<br />

CREB-Binding Protein (CBP)/p300 in respiratory epithelium tumourigenesis”,<br />

Cell Res, 17: 324-332, 2007.<br />

48) M.V. <strong>Karamouzis</strong>, F.A. Badra & A.G. Papavassiliou: “Breast cancer: the upgraded<br />

role of HER-3 and HER-4”, Int J Biochem Cell Biol, 39: 851-856, 2007.<br />

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49) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “The molecular<br />

basis of retinoids‟ use in breast cancer chemoprevention”, Cell Oncol, 29: 183-<br />

184, 2007.<br />

50) P.A. Konstantinopoulos, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Focus on<br />

acetylation: of histones and beyond, from cancer and beyond”, Expert Opin<br />

Investig Drugs, 16: 569-571, 2007.<br />

51) M.V. <strong>Karamouzis</strong>, S.A. Perez, D.V. Skarlos, A. Ardavanis, N.N. Sotiriadou, E.G.<br />

Iliopoulou, M.L. Salagianni, P.A. Sotiropoulou, G. Orfanos, C.N. Baxevanis, G.<br />

Rigatos & M Papamichail: “CD4+CD25+ Regulatory T Cell frequency in<br />

HER/neu positive and negative advanced stage breast cancer patients”, Clin<br />

Cancer Res, 13: 2714-2721, 2007.<br />

52) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “The role of<br />

STATs in lung carcinogenesis: an emerging target for novel therapeutics”, J Mol<br />

Med, 85: 427-436, 2007.<br />

53) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “Intriguing<br />

issues of EGFR targeting in head and neck cancer”, Ann Oncol, 18: 962, 2007.<br />

54) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “Epigenetics in<br />

respiratory epithelium carcinogenesis: prevention and therapeutic challenges”,<br />

Cancer Treat Rev, 33: 284-288, 2007.<br />

55) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou:<br />

“Compartmentalization of EGFR signalling might potentiate the optimal use of<br />

EGFR inhibitors in cancer therapeutics”, Br J Cancer, 96: 1924-1925, 2007.<br />

56) P.A. Konstantinopoulos, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Targeting<br />

post-translational modifications and functional regulation of the Ras superfamily<br />

of small G-proteins for anticancer drug development”, Nat Rev Drugs Discov,<br />

6:541-555, 2007.<br />

57) M.V. <strong>Karamouzis</strong>, J.R. Grandis & A. Argiris: “Therapies against epidermal<br />

growth factor receptor in aerodigestive carcinomas”. JAMA, 298: 70-82, 2007.<br />

58) P.A. Konstantinopoulos, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Selective<br />

modulation of the erythropoietic and tissue-protective effects of erythropoietin:<br />

time to reach the full therapeutic potential of erythropoietin”, BBA – Reviews on<br />

Cancer, 1776: 1-9, 2007.<br />

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59) M.V. <strong>Karamouzis</strong>, G. Ioannidis & G. Rigatos: “Quality of life in metastatic breast<br />

cancer patients under chemotherapy or supportive care: a single-institution<br />

comparative study”, Eur J Cancer Care, 16: 433-438, 2007.<br />

60) A. Argiris, S. Agarwala, M.V. <strong>Karamouzis</strong>, L.A. Burmeister & S.E. Carty: “A<br />

phase II trial of doxorubicin and interferon alpha 2b in advanced, non-medullary<br />

thyroid cancer, Invest New Drugs, 2007.<br />

61) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “Trastuzumab<br />

– Mechanism of action and use in clinical practice”, New Engl J Med, 357: 1664,<br />

2007.<br />

62) M.V. <strong>Karamouzis</strong> & A. Argiris: “Update on the role of EGFR inhibitors in cancer<br />

therapeutics”, Cancer Treat Res, 135: 257-275, 2007.<br />

63) P.A. Konstantinopoulos, G.P. Vandoros, M.V. <strong>Karamouzis</strong>, M. Gkermpesi, G.<br />

Sotiropoulou-Bonikou & A.G. Papavassiliou: “EGF-R is expressed and AP-1 and<br />

NF-KB are activated in stromal myofibroblasts surrounding colon<br />

adenocarcinomas paralleling expression of cyclooxygenase-2 and VEGF”, Cell<br />

Oncol, 29: 477-482, 2007.<br />

64) M.V. <strong>Karamouzis</strong>, A. Argiris & J.R. Grandis: “Clinical applications of gene<br />

therapy in head and neck cancer”, Curr Gene Ther, 7: 446-457, 2007.<br />

65) P.A. Konstantinopoulos, M.V. <strong>Karamouzis</strong>, A.G. Papatsoris & A.G.<br />

Papavassiliou: “Matrix metalloproteinase inhibitors as anticancer agents”, Int J<br />

Biochem Cell Biol, 40: 1156-1168, 2007.<br />

66) A. Argiris, M.V. <strong>Karamouzis</strong>, J. Johnson, D.E. Heron, D. Eibling, E. Cano, S.<br />

Urba, J, Gluckman Y. Wang & S. Agarwala: “A phase III randomized trial of<br />

postoperative radiotherapy with or without carboplatin in patients with high risk,<br />

locally advanced squamous cell carcinoma of the head and neck”, Laryngoscope,<br />

118: 444-449, 2007.<br />

67) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos, F.A. Badra & A.G. Papavassiliou:<br />

“SUMO and estrogen eceptors in breast cancer”, Breast Cancer Res Treat, 107:<br />

195-210, 2008.<br />

68) P.A. Konstantinopoulos, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou:<br />

“Thaizolidinediones and cardiovascular events: Is concomitant aspirin use a<br />

confounder?”, JAMA, 299: 1539, 2008.<br />

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69) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos & A.G. Papavassiliou: “ErbB/HER<br />

receptor family in breast cancer – The more we search the more we learn”, Ann<br />

Oncol, 19: 1020-1021, 2008.<br />

70) M.V. <strong>Karamouzis</strong>, A. Argiris, D. Raben & R. Ferris: “Head and Neck Cancer”,<br />

Lancet, 371: 1695-1709, 2008.<br />

71) G.P. Vandoros, T. Manolidis, M.V. <strong>Karamouzis</strong>, M. Gkermpesi, M.<br />

Lambropoulou, A.G. Papatsoris, I. Zachos & P.A. Konstantinopoulos:<br />

“Leiomyosarcoma of the prostate: case report and review of 54 previously<br />

published cases”. Sarcoma, 2008.<br />

72) P.A. Konstantinopoulos, M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Educational<br />

and Social-Ethical Issues in the Pursuit of Molecular Medicine”. Mol Med, 15: 60-<br />

63, 2009.<br />

73) Zachos I, Konstantinopoulos PA, Vandoros GP, <strong>Karamouzis</strong> MV, Papatsoris AG,<br />

Podimatas T, Papachristodoulou A, Chrisofos M, Deliveliotis C, Papavassiliou<br />

AG: “Predictive value of telomerase reverse transcriptase expression in patients<br />

with high risk superficial bladder cancer treated with adjuvant BCG<br />

immunotherapy”. J Cancer Res Clin Oncol, 135: 1169-75, 2009.<br />

74) M.V. <strong>Karamouzis</strong>, S. Moschos: “Endostatin in cancer therapeutics”, Expert Opin<br />

Biol Ther , 9: 641-648, 2009.<br />

75) D.E. Heron, R.L. Ferris, M.V. <strong>Karamouzis</strong>, R.S. Andrade, E.L. Deeb, S. Burton,<br />

W.E. Gooding, B.F. Branstetter, J.M. Mountz, J.T. Johnson, A. Argiris, J.R.<br />

Grandis, S.Y. Lai: „Stereotactic Body Radiotherapy for Recurrent Squamous Cell<br />

Carcinoma of the Head and Neck: Results of a Phase I Dose-Escalation Trial”. Int<br />

J Radiat Oncol Biol Phys, 75: 1493-500, 2009.<br />

76) M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos, A.G. Papavassiliou: “Targeting c-Met<br />

as a strategy to overcome cross-talk related resistance to EGFR protein -targeting<br />

agents in cancer therapeutics”, Lancet Oncol, 10: 709-77, 2009.<br />

77) A.G. Pallis, M.V. <strong>Karamouzis</strong>, P.A. Konstantinopoulos, A.G. Papavassiliou:<br />

“Moleular networks in respiratory epithelium carcinomas”, Cancer Lett, 95: 1-6,<br />

2010.<br />

78) I. Zachos, P.A. Konstantinopoulos, V. Tzortzis, S. Gravas, A. Karatzas, M.V.<br />

<strong>Karamouzis</strong>, M. Melekos, AG. Papavassiliou: “Systemic therapy of metastatic<br />

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ladder cancer in the molecular era: current status and future promise”, Expert<br />

Opin Investig Drugs, 19: 875-87, 2010.<br />

79) A. Kotsinas, I.S. Pateras, P.S. Galanos, M.V. <strong>Karamouzis</strong>, P.P. Sfikakis, V.G.<br />

Gorgoulis: “Why is p53-inducible gene 3 rarely affected in cancer?”, Oncogene,<br />

29: 5220, 2010.<br />

80) E.G. Iliopoulou, P. Kountourakis, M.V. <strong>Karamouzis</strong>, D. Doufexis, A. Ardavanis,<br />

C.N. Baxevanis, G. Rigatos,M. Papamichail, S.A. Perez: “A phase I trial of<br />

adoptive transfer of allogeneic natural killer cells in patients with advanced non-<br />

small cell lung cancer”, Cancer Immunol Immunother, 59: 1781-89, 2010.<br />

81) A.G. Pallis, M.V. <strong>Karamouzis</strong>: “DNA repair pathways and their implication in<br />

cancer treatment”, Cancer Metastasis Rev, 29: 677-85, 2010.<br />

82) Argiris, M.V. <strong>Karamouzis</strong>, W.E. Gooding, B.F. Branstetter, S. Zhong, L.E. Raez,<br />

P. Savvides, M. Romkes: “Phase II trial of pemetrexed and bevacizumab in<br />

patients with recurrent or metastatic head and neck cancer”, J Clin Oncol, 29:<br />

1140-45. 2011.<br />

83) Argiris, M.V. <strong>Karamouzis</strong>: “Empowering induction therapy for locally advanced<br />

head and neck cancer”, Ann Oncol, 22: 773-781, 2011.<br />

84) Argiris, M.V. <strong>Karamouzis</strong>, R. Smith, A. Kotsakis, M.K. Gibson, S.Y. La, S. Kim,<br />

B.F. Branstetter, Y. Shuai, M. Romkes, L. Wang, J.R. Grandis, R.L. Ferris, J.T.<br />

Johnson & D.E. Heron: “Phase I trial of pemetrexed in combination with<br />

cetuximab and concurrent radiotherapy in patients with head and neck cancer”,<br />

Ann Oncol, 22: 2482-2488, 2011.<br />

85) M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Transcription Factor Networks as<br />

Targets for Therapeutic Intervention of Cancer - The Breast Cancer Paradigm”,<br />

Mol Med 2011.<br />

86) M.V. <strong>Karamouzis</strong> & A.G. Papavassiliou: “Targeting insulin-like growth factor in<br />

breast cancer therapeutics”, Crit Rev Oncol Hematol, 2012, in press.<br />

Abstracts in international congresses<br />

1) M.V. <strong>Karamouzis</strong>, et al.: “Circulating Regulatory T Cells in Advanced Breast<br />

Cancer Patients”, 42 th ASCO Annual Meeting, Atlanda, Giorgia, U.S.A., June 2-6,<br />

2006.<br />

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2) E.G. Iliopoulou, M.V. <strong>Karamouzis</strong>, et al.: “Characterization of a subset of CD4+ T<br />

cells expressing CD161 in cancer patients and healthy individuals”, 42 th ASCO<br />

Annual Meeting, Atlanda, Giorgia, U.S.A., June 2-6, 2006.<br />

3) M.V. <strong>Karamouzis</strong>, et al.: “Phase II trial of pemetrexed (P) and bevacizumab (B) in<br />

patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma<br />

(HNSCC): an interim analysis”, 43 th ASCO Annual Meeting, Chicago, Illinois,<br />

U.S.A., June 1-5, 2007.<br />

4) R. Smith, M.V. <strong>Karamouzis</strong>, et al.: “Phase I trial of pemetrexed (P) in<br />

combination with cetuximab (C) and concurrent radiotherapy (RT) in patients<br />

(pts) with head and neck cancer (HNC)”, 43 th ASCO Annual Meeting, Chicago,<br />

Illinois, U.S.A., June 1-5, 2007.<br />

5) J. Johnson, S. Agarwala, M.V. <strong>Karamouzis</strong>, et al.: “Phase III randomized trial of<br />

postoperative radiotherapy (RT) with or without carboplatin (Cb) in patients (pts)<br />

with head and neck squamous cell carcinoma (HNSCC)”, 43 th ASCO Annual<br />

Meeting, Chicago, Illinois, U.S.A., June 1-5, 2007.<br />

6) D.E. Heron, R.L. Ferris, S. Burton, S. Lai, M.V. <strong>Karamouzis</strong>, et al.: “Phase I dose<br />

escalation study of fractionated stereotactic radiosurgery (fSRS) for recurrent<br />

squamous cell carcinoma of the head and neck (SCCHN)”, 43 th ASCO Annual<br />

Meeting, Chicago, Illinois, U.S.A., June 1-5, 2007.<br />

7) Argiris, M.V. <strong>Karamouzis</strong>, et al.: “Phase II trial of docetaxel (T), cisplatin (P), and<br />

cetuximab (E) followed by concurrent radiation (RT), P, and E in locally advanced<br />

head and neck squamous cell carcinoma (HNSCC), 43 th ASCO Annual Meeting,<br />

Chicago, Illinois, U.S.A., June 1-5, 2007.<br />

8) M. Gibson, M.V. <strong>Karamouzis</strong>, et al.: “Phase I trial of pemetrexed in combination<br />

with cetuximab and concurrent radiotherapy in head and neck cancer (HNC), 49 th<br />

ASTRO Annual Meeting, Los Angeles, California, U.S.A., October 28-November<br />

1, 2007.<br />

9) S.C. Buch, M.V. <strong>Karamouzis</strong>, et al.: “Gene expression signatures correlate with<br />

survival of patients with head and neck cancer treated with platinum-based<br />

regimens”, AACR Annual Meeting, San Diego, California, U.S.A., April 12-16,<br />

2008.<br />

10) T. Feinstein, L. Raez, K. Rajasenan, M. Gibson, P. Savvides, M.V. <strong>Karamouzis</strong>, et<br />

al.: “Pemetrexed (P) and bevacizumab (B) in patients (pts) with recurrent or<br />

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metastatic head and neck squamous cell carcinoma (HNSCC): updated results of a<br />

phase II trial”, 44 th ASCO Annual Meeting, Chicago, Illinois, U.S.A., May 30-<br />

June 3, 2008.<br />

11) E. G. Iliopoulou, P. Kountourakis, M. V. <strong>Karamouzis</strong>, et al.: “A phase I trial of<br />

adoptive transfer of allogeneic natural killer (NK) cells in patients (pts) with<br />

advanced non-small cell lung cancer (NSCLC)”, ASCO Annual Meeting, Orlando,<br />

Florida, U.S.A., May 29-June 2, 2009.<br />

12) A. Argiris, M.V. <strong>Karamouzis</strong>, W.E. Gooding, B. Branstetter, S. Zhong, L.E. Raez,<br />

P. Savvides, M. Romkes: “Pemetrexed (P) and bevacizumab (B) in patients (pts)<br />

with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck<br />

(SCCHN): Final results and correlation with TS, MTHFR, and VEGF gene<br />

polymorphisms”, ASCO Annual Meeting, Chicago, Illinois, U.S.A., June, 2010.<br />

13) M.V. <strong>Karamouzis</strong>, N. Dioufa, E. Farmaki, C. Piperi, H. Kiaris, A. Papavassiliou:<br />

“Essential role of p53 of stromal fibroblasts (fibs) in the reciprocal interaction<br />

between PC3 prostate cancer cells and stromal fibs”, ASCO Annual Meeting,<br />

Chicago, Illinois, U.S.A., June, 2011.<br />

Participation in scientific societies<br />

1) Full ESMO Member (European Society of Medical Oncology) – Chair of ESMO-<br />

Young Oncologists Committee (2010-2012)<br />

2) Active ASCO Member (American Society of Clinical Oncology).<br />

3) Associate AACR Member (American Association of Cancer Research).<br />

Last Update: October 2012<br />

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