2 - BACTERIOWEB
2 - BACTERIOWEB
2 - BACTERIOWEB
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Expression<br />
System NorA in S. aureus<br />
– Constitutive or slightly inducible by FQs in wild-type strains<br />
– Increased by mutations in the promoter region of norA or in<br />
other loci<br />
Substrates<br />
– Identical to those of pump Bmr in Bacillus subtilis<br />
– Specificity related to C-7 residue and hydrophobicity of C-8<br />
residue<br />
Inhibitors<br />
– CCCP, nigericin, nigericin,<br />
reserpin, reserpin,<br />
verapamil, verapamil,<br />
omprazole, omprazole<br />
lanzoprazole<br />
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