2 - BACTERIOWEB

Efflux-based resistance in Staphylococci
Species System Family Substrates Genes Fqcy r
S. coagulase - MsrA ABC 14,15-M, strept.B P ++
S. aureus MsrA-like ABC 14,15-M, strept.B P +/-
S. epidermidis ErpA ABC ? 14,15-M P ?
S. aureus NorA MFS Fq, Cmp, Org. Ch ?
S. aureus QacA/B MFS Antisept. P +
S. aureus TetK MFS Tc P +++
14,15-M: 14 et 15-macrolides ; Strept.B: streptogramin B ; Fq: fluoroquinolones ; Cmp: chloramphenicol;
Organic cations.: acriflavin, cetyltrimethylammonium, Ethidium bromide, triphenylphosphonium, rhodamine ;
Antisept.: chlorhexidin, benzalkonium, cetyltrimethylammonium, pentamidine...; Tc: tetracycline.
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