2 - BACTERIOWEB

More documents

Recommendations

Info

H + Structure of drug efflux systems Na + antibiotic ATP ADP antibiotic MFS, SMR MATE ABC RND (MFS, ABC) H + 14
Efflux-based resistance in Staphylococci Species System Family Substrates Genes Fqcy r S. coagulase - MsrA ABC 14,15-M, strept.B P ++ S. aureus MsrA-like ABC 14,15-M, strept.B P +/- S. epidermidis ErpA ABC ? 14,15-M P ? S. aureus NorA MFS Fq, Cmp, Org. Ch ? S. aureus QacA/B MFS Antisept. P + S. aureus TetK MFS Tc P +++ 14,15-M: 14 et 15-macrolides ; Strept.B: streptogramin B ; Fq: fluoroquinolones ; Cmp: chloramphenicol; Organic cations.: acriflavin, cetyltrimethylammonium, Ethidium bromide, triphenylphosphonium, rhodamine ; Antisept.: chlorhexidin, benzalkonium, cetyltrimethylammonium, pentamidine...; Tc: tetracycline. 15
Page 1 and 2: Role of the Efflux Pumps in Antimic
Page 3 and 4: Cell wall Bacterial targets for ant
Page 5 and 6: Drug inactivation Target alteration
Page 7 and 8: Intracellular accumulation Drug acc
Page 9 and 10: 9 Other bacterial species with know
Page 11 and 12: Structure of bacterial efflux syste
Page 13: PMF secondary transporters Major F
Page 17 and 18: System NorA in S. aureus Antibiotic
Page 19 and 20: Combination of mechanisms in S. aur
Page 21 and 22: PmrA-mediated resistance in S. pneu
Page 23 and 24: Other Gram positives Species System
Page 25 and 26: 25 Efflux pumps coded by mobile gen
Page 27 and 28: Efflux pumps of the RND family Bact
Page 29 and 30: System AcrAB-TolC in E. coli Antibi
Page 31 and 32: Induction of acrAB-tolC expression
Page 33 and 34: RND efflux systems in P. aeruginosa
Page 35 and 36: Acquired resistance in P. aeruginos
Page 37 and 38: MexXY-mediated adaptive resistance
Page 39 and 40: Therapeutic implications of efflux
Page 41: Efflux inhibitors Phenyl-Arginyl ß

2 - BACTERIOWEB

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?