Migrating from ISIS to Isentris - Accelrys

Migrating from ISIS to Isentris
Success stories

Isentris migration strengths
Ability to run Isentris and ISIS concurrently
• Migration can proceed at your desired pace
• No need to “throw a switch”
Symyx has managed migrations before
• MACCS-II and REACCS to ISIS
• MACCS-II to Direct
• Much learned re: strategy of migration
Experienced Field organization
• Can assess, advise, plan, teach, implement

ISIS and Isentris work together
Isentris supports a phased transition
• Isentris accesses RCG databases
• Registration, inventory, catalogs
• Isentris runs your Cheshire scripts
• Isentris can open ISIS hviews
• Isentris opens ISIS for Excel spreadsheets
• Isentris reads ISIS lists
• Isentris opens ISIS sketches
• Isentris 3.1 delivers local databases!

Isentris adds value to the scientist over ISIS
Isentris does more than ISIS
• Clustering New!
• Enumeration support New!
• Local databases New!
• Structure searchable spreadsheets New!
• Availability flags
• Biomolecules
• Dynamic data access
• History tree
• Presentation-quality graphics
• Reaction planner
• Reporting
• SAR tables with visualization
• Shopping carts
• Spotfire integration

Assess the portfolio
Assessment of existing applications
• Are there additional requirements?
• Are there gaps or unmet needs?
• Have business processes changed?
• Is there a need to streamline?
• Is there a need to merge functionality?
Identify “hidden gems”
• Are there unrecognized lab based or personal applications?
Coordinate future & legacy applications to be migrated
• Are there services can be shared?
Estimate benefit of streamlining / consolidation
• Are there applications that can be merged?
• Are there applications that can be decommissioned?

Example Action Plan
Phase 1: Quick wins in first 3 months
Kickoff Standard desktop
validation
Goals
Isentris
client
• Replace ISIS finders
• Replace ISIS for Excel
• Improved access to
data in Excel
• Standard desktop
validation
Isentris
For Excel
Seminars:
NJ, CA, UK
Benefits
• Synthesis planning
• Links between reactions
and ACD
• Single interface to
molecule and reaction
databases
• Interactive SAR tables
• More than just “retrieve
structure”
• Performance!

Example Action Plan
Phase 2: Project team views
Goals
Developer
Training
Project #1
IDS
• Replace ISIS RAFS for
internal data
• Improved access to
data in Excel
• Integrate with desktop
calculators
Dynamic
IDS
SAR
extensions
Seminars:
NJ, CA, UK
Benefits
• Interactive SAR tables
• Project team dashboard
• Integrated desktop
• Reporting
• …
• Performance!

Project-based transition
Customers are making the
transition this way today
• Next generation SAR
• Integration of domain data and
expert tools
• Registration and Logistics
An active project or initiative is
the best migration approach
• Provides a way to show value
• Has business buy in and visibility
• Has a dedicated team
• Has a goal and budget
SAR SAR Projects
Top-10, Top-10, Leading Leading Biotech, Biotech,
Leading Leading Biotech Biotech
Critical Critical business business issues issues
•• Access Access to to project project data data
•• Access Access scientific scientific services services
•• Quickly Quickly locate locate results results
•• Enable Enable decision decision workflows workflows
•• Share Share information information
•• Collaborate Collaborate
Result Result
•• Save Save scientists scientists time time
•• Support Support project project team
team

Access to Project Data

Solution: Quick review

Solution: SAR Table

Solution: Add more information on the fly

Solution: Drill down into details

Search and report

Project team meeting
Produce reports in minutes instead of hours

Project-based transition
Customers are making the
transition this way today
• Next generation SAR
• Integration of domain data and
expert tools
• Registration and Logistics
Integration Projects
Top Top Pharma, Pharma, Biotech Biotech Company Company
Critical Critical business business issues issues
•• Access Access computational computational tools tools
•
•
Pipeline
Pipeline
pilot,
pilot,
web
web
services,
services,
...
...
•
•
Chemical
Chemical
properties
properties
•• Access Access data data services services
•
•
Sharepoint,
Sharepoint,
Documentum
Documentum
•
•
LIMS
LIMS
•• Access Access chemical chemical cartridges cartridges
•
•
Accelrys
Accelrys
cartridge
cartridge
•
•
Daylight
Daylight
cartridge
cartridge
Result: Result:
•• Utilization Utilization of of corporate corporate
resources resources
•• Unlock Unlock specialist specialist tools
tools

Access to Computational Services

Project-based transition
Customers are making the
transition this way today
• Next generation SAR
• Integration of domain data and
expert tools
• Registration and Logistics
Registration / Logistics
Projects
Top Top 10 10 Pharma, Pharma, Top Top 30 30 Pharma Pharma
Critical Critical business business issues issues
•• Integrated Integrated workflow workflow
•
•
ELN
ELN
integration
integration
•
•
Sample
Sample
distribution
distribution
•
•
Analytical
Analytical
requests
requests
•
•
SAP,
SAP,
Ariba
Ariba
integration
integration
•• Support Support outside outside organizations
organizations
•• Support Support operations operations
Result: Result:
•• Save Save scientists scientists time time
•• Streamline Streamline process process of of getting getting
samples samples tested tested
•• Save Save organization organization money
money

Manage inventory and sales

Produce catalogs

Summary
Isentris completely replaces ISIS and
does more:
• Clustering New!
• Enumeration support New!
• Local databases New!
• Structure searchable spreadsheets New!
• Availability flags
• Biomolecules
• Dynamic data access
• History tree
• Presentation-quality graphics
• Reaction planner
• Reporting
• SAR tables with visualization
• Shopping carts
• Spotfire integration

Success: Solving R&D challenges
“With Isentris we’ve been able to retain our critical ISIS functionality, while moving to a system with
much improved integration and ease-of-use. The new system is demonstrating its power, enabling
scientists to access new assay types and related experimental data as soon as they are
created…”
Carlo Riva of Recordati
22