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CDC History of Tuberculosis Control - Medical and Public Health ...

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efugee is informed <strong>of</strong> the need to be further<br />

evaluated for their TB <strong>and</strong> to report to the<br />

local health department as soon as possible<br />

after arrival. Persons with Class A TB are<br />

required to report to the local health<br />

department, present all medical records <strong>and</strong><br />

chest x-rays from overseas, <strong>and</strong> submit to the<br />

necessary testing, isolation, <strong>and</strong> treatment<br />

until discharged. They risk deportation<br />

should they fail to do so. For persons having<br />

Class B1 or B2 TB, the health department visit<br />

is considered voluntary.<br />

Many health departments in the United States<br />

perform active follow-up <strong>of</strong> arrivals designated<br />

as having Class B1 or B2 TB, on the basis <strong>of</strong><br />

the DQ notification. Studies conducted in the<br />

mid-1990s by the Division <strong>of</strong> TB Elimination,<br />

DQ, <strong>and</strong> health departments in various parts<br />

<strong>of</strong> the country have shown from 3% to 14% <strong>of</strong><br />

Class B1 immigrants <strong>and</strong> refugees were<br />

diagnosed with TB disease within one year <strong>of</strong><br />

their arrival; between 0.4% to 4.0% <strong>of</strong> those<br />

with Class B2 TB were diagnosed with TB<br />

disease within one year <strong>of</strong> arrival. Of the<br />

remaining persons, many are high-priority<br />

c<strong>and</strong>idates for preventive therapy regardless <strong>of</strong><br />

their age because they are tuberculin skin test<br />

positive with an abnormal chest x-ray<br />

suggestive <strong>of</strong> TB disease.<br />

The current overseas TB evaluation<br />

procedures described above are based upon the<br />

following three principles: 1) the requirements<br />

apply specifically to immigrants <strong>and</strong> refugees,<br />

as they are most likely to become permanent<br />

US residents; 2) the procedures reduce the<br />

importation <strong>of</strong> active infectious TB that poses<br />

an immediate public health risk by denying<br />

admission to persons who have positive<br />

sputum smears; <strong>and</strong> 3) they allow those<br />

persons with evidence <strong>of</strong> TB disease but whose<br />

smears are negative to enter the United States,<br />

where a more complete medical evaluation can<br />

be performed <strong>and</strong> appropriate treatment can<br />

be provided under supervision. Forcing<br />

immigrants <strong>and</strong> refugees with noninfectious<br />

TB to undergo treatment overseas could prove<br />

TB <strong>Control</strong> at the Millennium<br />

70<br />

to be counter-productive, as it may be difficult<br />

to ensure that the drug regimens are adequate,<br />

<strong>and</strong> that applicants are regularly ingesting the<br />

required medications. In such a scenario,<br />

incomplete treatment as well as development<br />

<strong>of</strong> drug resistance may be the result.<br />

The overseas screening process for identifying<br />

<strong>and</strong> treating TB in immigrants <strong>and</strong> refugees is<br />

responsible for the identification <strong>of</strong> substantial<br />

numbers <strong>of</strong> persons arriving in the United<br />

States who have active TB. However, not all<br />

cases in newly arrived immigrants or refugees<br />

were identified overseas as having suspect TB,<br />

which is in part due to several limitations <strong>of</strong><br />

the screening process. Although panel<br />

physicians do function under a contractual<br />

agreement with their respective US consulates,<br />

they receive no formal training or certification<br />

per se. In 1997, a training needs assessment was<br />

performed on a sample <strong>of</strong> panel physicians in a<br />

study undertaken by the Division <strong>of</strong> TB<br />

Elimination <strong>and</strong> DQ. The assessment<br />

indicated that, although 98% <strong>of</strong> panel<br />

physicians in the sample understood which<br />

immigrants <strong>and</strong> refugees should receive a chest<br />

x-ray, over 60% indicated a need for training.<br />

Presently, efforts are underway to develop selfstudy<br />

training materials for panel physicians to<br />

enhance their ability to diagnose <strong>and</strong> treat TB,<br />

<strong>and</strong> to improve their ability to monitor the<br />

performance <strong>of</strong> contracted laboratory <strong>and</strong><br />

radiologic services. A training plan will be<br />

developed, <strong>and</strong> self-study materials will be<br />

pilot-tested later this year in countries with<br />

large numbers <strong>of</strong> persons who immigrate to<br />

the United States <strong>and</strong> have a high TB<br />

prevalence.<br />

The STOP TB Initiative,<br />

A Global Partnership<br />

by Bess Miller, MD, MSc<br />

Associate Director for Science, DTBE<br />

Over the past few decades, when we have<br />

looked at the agendas <strong>of</strong> international health

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