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CDC History of Tuberculosis Control - Medical and Public Health ...

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skin test. All 11 contacts with positive TST<br />

who were on the April flights <strong>and</strong> 2 <strong>of</strong> 3<br />

contacts with positive TST on the Baltimoreto-Chicago<br />

flight in May had other risk factors<br />

for tuberculosis. More contacts on the 8.75<br />

hour flight from Chicago to Honolulu had a<br />

positive TST than on the other three flights.<br />

Of 15 contacts with a positive TST on the<br />

Chicago-to-Honolulu flight, six (four with<br />

skin-test conversions) had no other risk<br />

factors; all six sat in the same section as the<br />

index patient. Passengers seated within two<br />

rows <strong>of</strong> the index patient were more likely to<br />

have a positive TST than those in the rest <strong>of</strong><br />

the section. Transmission <strong>of</strong> M. tuberculosis in<br />

this setting involved a highly infectious<br />

passenger, a long flight, <strong>and</strong> close proximity <strong>of</strong><br />

contacts to the index patient.<br />

The Division <strong>of</strong> TB Elimination <strong>and</strong> our<br />

partners in state <strong>and</strong> local health departments<br />

have benefitted tremendously from what has<br />

been learned from these <strong>and</strong> other outbreaks.<br />

Our continued cooperation, diligence, <strong>and</strong><br />

timely systematic response to future outbreaks<br />

are critical to our eventual success in<br />

eliminating TB from the United States.<br />

International Activities<br />

by Nancy Binkin, MD, MPH,<br />

Chief, International Activity <strong>and</strong><br />

Michael Iademarco, MD, MPH<br />

International Activity<br />

As the rate <strong>of</strong> tuberculosis (TB) cases falls in<br />

the United States (US), an increasing<br />

percentage <strong>of</strong> TB cases occur among US<br />

residents born in countries with a higher<br />

burden <strong>of</strong> TB. The US rate <strong>of</strong> TB cases is<br />

relatively low compared with the rate in 22<br />

high-burden countries where 80% <strong>of</strong> global TB<br />

cases occur <strong>and</strong> where 62% <strong>of</strong> the world’s<br />

population resides. Given the latency period<br />

between TB infection <strong>and</strong> disease, continued<br />

immigration into the US, <strong>and</strong> increasing<br />

international travel, efforts to eliminate TB in<br />

the US must extend beyond our geographical<br />

borders. Recognition <strong>of</strong> the public health<br />

Notable Events in TB <strong>Control</strong><br />

65<br />

impact <strong>of</strong> the global TB epidemic led <strong>CDC</strong> to<br />

<strong>of</strong>ficially organize an International Activity<br />

within the Division <strong>of</strong> TB Elimination<br />

(DTBE) in 1994 as international efforts are<br />

part <strong>of</strong> the overall strategic plan <strong>of</strong> DTBE.<br />

The mission <strong>of</strong> the International Activity is,<br />

first, to provide leadership <strong>and</strong> coordination<br />

for <strong>CDC</strong> activities related to improving TB<br />

prevention <strong>and</strong> control efforts among foreignborn<br />

persons in the US. Its mission is, second,<br />

to contribute to global TB prevention <strong>and</strong><br />

control efforts by conducting operations<br />

research <strong>and</strong> providing technical support to<br />

high-priority countries, i.e., those that have a<br />

major TB burden or that are <strong>of</strong> strategic<br />

interest for TB control efforts in the US.<br />

Coordination <strong>and</strong> collaboration with other<br />

international public health partners are critical<br />

to accomplish our mission.<br />

Immigrants from Mexico, the Philippines, <strong>and</strong><br />

Viet Nam are the leading contributors to the<br />

US foreign-born TB case burden <strong>and</strong> therefore<br />

constitute a high priority for TB control<br />

efforts in the US. The aim <strong>of</strong> International<br />

Activity efforts in these countries is to reduce<br />

the burden <strong>of</strong> TB by improving the TB<br />

control capacity <strong>of</strong> the respective national<br />

programs, by providing technical assistance<br />

<strong>and</strong> contributing to human resource<br />

development.<br />

Historically<br />

efforts in<br />

Mexico <strong>and</strong><br />

the<br />

Philippines<br />

have been<br />

hampered by<br />

ongoing<br />

political <strong>and</strong><br />

social changes. More recently, however,<br />

progress has been made.<br />

Mexico<br />

Because <strong>of</strong> their proximity <strong>and</strong> our shared<br />

border, persons born in Mexico represent the<br />

single largest group <strong>of</strong> foreign-born persons in

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