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CDC History of Tuberculosis Control - Medical and Public Health ...

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issue<br />

recommendations,<br />

OSHA has the<br />

capacity to enforce its<br />

st<strong>and</strong>ards. In 1997,<br />

OSHA published a<br />

draft TB st<strong>and</strong>ard in<br />

the Federal Register.<br />

Following the<br />

publication <strong>of</strong> the<br />

draft st<strong>and</strong>ard, there<br />

was a period for<br />

public comment<br />

followed by a series <strong>of</strong> hearings for testimony.<br />

Detailed comments were submitted from a<br />

<strong>CDC</strong> committee including staff members <strong>of</strong><br />

NIOSH, the Hospital Infections Program, <strong>and</strong><br />

the Division <strong>of</strong> <strong>Tuberculosis</strong> Elimination, as<br />

well as many other pr<strong>of</strong>essional organizations.<br />

In July 1999, OSHA reopened the docket for<br />

further public comment. The OSHA TB<br />

st<strong>and</strong>ard is currently undergoing revision, <strong>and</strong><br />

its final content <strong>and</strong> release date are not yet<br />

known.<br />

In order to better underst<strong>and</strong> the risk <strong>of</strong><br />

transmission <strong>of</strong> M. tuberculosis to health care<br />

workers, <strong>CDC</strong> undertook several studies<br />

designed to examine rates <strong>of</strong> skin test<br />

conversions in health care workers. The most<br />

comprehensive <strong>of</strong> these was a study initiated<br />

in 1995 called StaffTRAK-TB. This study<br />

included over 13,000 health care workers.<br />

Data from this study demonstrate a rate <strong>of</strong><br />

skin test conversions among health care<br />

workers <strong>of</strong> 4.4 conversions per 1,000 personyears<br />

<strong>of</strong> follow-up. For US-born persons, the<br />

rate was even lower at 3.2 conversions per<br />

1,000 person-years. From data currently<br />

available from studies such as StaffTRAK-TB,<br />

the risk <strong>of</strong> nosocomial transmission <strong>of</strong> TB<br />

appears to be quite low. As a result <strong>CDC</strong> is<br />

considering revision <strong>of</strong> the 1994 guidelines,<br />

especially in the areas <strong>of</strong> frequency <strong>of</strong><br />

tuberculin skin testing <strong>of</strong> health care workers.<br />

The risk <strong>of</strong> transmission <strong>of</strong> M. tuberculosis in<br />

health care settings is a real one. However, the<br />

TB <strong>Control</strong> at the Millennium<br />

62<br />

magnitude <strong>of</strong> this risk depends on many<br />

factors such as implementation <strong>of</strong><br />

administrative <strong>and</strong> engineering controls,<br />

prevalence <strong>of</strong> patients with infectious TB<br />

within the facility, <strong>and</strong> risk for infection<br />

outside <strong>of</strong> the healthcare facility. All <strong>of</strong> these<br />

factors need to be weighed in decisions<br />

regarding recommendations or m<strong>and</strong>ates for<br />

TB control measures within health care<br />

facilities. As the rates <strong>of</strong> TB in the US<br />

continue to decline, these recommendations<br />

will need to be tailored to <strong>of</strong>fer protection to<br />

patients <strong>and</strong> workers within the health care<br />

setting, without an unnecessary burden <strong>of</strong><br />

testing <strong>and</strong> expense.<br />

A Decade <strong>of</strong> Notable TB Outbreaks:<br />

A Selected Review<br />

by Scott B. McCombs, MPH<br />

Deputy Chief, Surveillance <strong>and</strong> Epidemiology Branch<br />

The Surveillance <strong>and</strong> Epidemiology Branch is<br />

charged with monitoring TB morbidity <strong>and</strong><br />

mortality in cooperation with state <strong>and</strong> local<br />

health departments. One <strong>of</strong> the most<br />

fascinating <strong>and</strong> important parts <strong>of</strong> our role is<br />

to assist our partners in responding to<br />

outbreaks <strong>of</strong> TB when they occur. This article<br />

summarizes a cross-section <strong>of</strong> some <strong>of</strong> the<br />

more notable outbreaks from the 1990s.<br />

Extensive transmission <strong>of</strong> Mycobacterium<br />

tuberculosis from a child (Curtis, Ridzon,<br />

Vogel, et al. N Engl J Med 1999;341:1491-<br />

1495).<br />

Although young children rarely transmit TB,<br />

infectious TB was diagnosed in a 9-year-old<br />

boy in North Dakota in July 1998. The child<br />

was screened because extrapulmonary TB was<br />

diagnosed in his female guardian. The child,<br />

who had come from the Republic <strong>of</strong> the<br />

Marshall Isl<strong>and</strong>s in 1996, had bilateral cavitary<br />

TB. Because he was the only known possible<br />

source <strong>of</strong> his guardian’s TB, an investigation <strong>of</strong><br />

the child’s contacts was undertaken. Family,<br />

school, day-care, <strong>and</strong> other social contacts<br />

were notified <strong>of</strong> their exposure <strong>and</strong> given<br />

tuberculin skin tests (TST). Of the 276

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