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CDC History of Tuberculosis Control - Medical and Public Health ...

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Where We’ve Been <strong>and</strong><br />

Where We’re Going:<br />

Perspectives from <strong>CDC</strong><br />

Early <strong>History</strong> <strong>of</strong> the <strong>CDC</strong> TB Division,<br />

1944 - 1985<br />

by John Seggerson<br />

Associate Dir. for External Relations, DTBE<br />

In 1944, Congress passed the <strong>Public</strong> <strong>Health</strong><br />

Service Act, which authorized grants to the<br />

states for TB control <strong>and</strong> established the<br />

“Division <strong>of</strong> <strong>Tuberculosis</strong> <strong>Control</strong>,” then<br />

located in Washington, DC. At the time <strong>of</strong> the<br />

creation <strong>of</strong> the TB Division, TB drugs were<br />

not available, <strong>and</strong> the primary method <strong>of</strong> TB<br />

control was the isolation <strong>of</strong> persons with<br />

active disease in TB sanatoria where they were<br />

“treated” with healthful living, bed rest,<br />

calorie-laden meals, fresh air, sunshine, <strong>and</strong><br />

sometimes with surgery <strong>and</strong>/or collapsed lung<br />

therapy.<br />

PHS mobile x-ray unit<br />

From the beginning <strong>of</strong> the 20th century, the<br />

National <strong>Tuberculosis</strong> Association (later the<br />

American Lung Association), <strong>and</strong> its state <strong>and</strong><br />

local affiliates, played a major role in establishing<br />

<strong>and</strong> supporting the TB sanatorium movement<br />

in the US. During the post-WW II<br />

period <strong>and</strong> into the 1950s, TB associations <strong>and</strong><br />

health departments employed small-film x-ray<br />

units to conduct TB screening in general<br />

populations, with one x-ray unit <strong>of</strong>ten screening<br />

as many as 500 persons per day. The<br />

TB <strong>Control</strong> at the Millennium<br />

42<br />

screening did not effectively cover large city<br />

populations <strong>and</strong> by 1947, the PHS Division <strong>of</strong><br />

TB <strong>Control</strong> was operating mobile x-ray unit<br />

teams in some 20 cities <strong>of</strong> more than 100,000<br />

population which participated in this PHS big<br />

city program. By 1953, after some 20 million<br />

people had been x-rayed for TB, the program<br />

was discontinued owing to declining yield <strong>and</strong><br />

high cost. Many health department <strong>and</strong> TB<br />

association community x-ray screening programs<br />

were also discontinued, although some<br />

continued until the late 1960s.<br />

In 1959, a group <strong>of</strong> nationally recognized TB<br />

experts was convened in Harriman, New<br />

York, to review the status <strong>of</strong> US TB control,<br />

<strong>and</strong> they issued the “Arden House Report,”<br />

which recommended the eradication <strong>of</strong> TB<br />

with effective treatment programs to cure<br />

disease <strong>and</strong> prevent spread. The Arden House<br />

group also recommended isoniazid treatment<br />

<strong>of</strong> latent TB infection based on extensive PHS<br />

chemoprophylaxis trials.<br />

In late 1960, the PHS TB program, by then<br />

renamed the “<strong>Tuberculosis</strong> Branch,” was<br />

transferred from Washington, DC, to Atlanta,<br />

to what was then called the Communicable<br />

Disease Center. The TB research activity<br />

remained in Washington for the time being,<br />

then was also transferred to Atlanta in the<br />

early 1970s.<br />

In the 1960s it became increasingly obvious<br />

that long-term hospitalization <strong>of</strong> patients with<br />

active TB was no longer necessary because <strong>of</strong><br />

the availability <strong>of</strong> effective chemotherapy, <strong>and</strong><br />

the TB Branch began to advocate that patients<br />

receive most or all <strong>of</strong> their care on an outpatient<br />

basis. The sanatoria began to close,<br />

with most <strong>of</strong> them being closed by the end <strong>of</strong><br />

the 1970s. It has been estimated that the<br />

closing <strong>of</strong> the sanatoria represented a savings<br />

<strong>of</strong> more than $400 million to state <strong>and</strong> local<br />

governments.<br />

In 1963, in response to a special Surgeon<br />

General’s Task Force report on TB, categori-

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