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CDC History of Tuberculosis Control - Medical and Public Health ...

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Conferences specifically addressing TB<br />

followed in Paris in 1888, 1891, 1892, <strong>and</strong><br />

1898. The 1899 conference took place in Berlin<br />

<strong>and</strong>, for the first time, <strong>of</strong>ficial representatives<br />

from both governments <strong>and</strong> nongovernmental<br />

agencies were present. The independent<br />

developments <strong>of</strong> sanatoria (1854), the<br />

discovery <strong>of</strong> the bacillus (1882), the opening <strong>of</strong><br />

TB dispensaries (1887), the development <strong>of</strong> the<br />

voluntary movement (1890), <strong>and</strong> the<br />

organization <strong>of</strong> periodic conferences called for<br />

a centralized agency for coordination <strong>and</strong><br />

communication. The Central Bureau for<br />

Prevention <strong>of</strong> <strong>Tuberculosis</strong> was formalized in<br />

Berlin in 1902, <strong>and</strong> the double-barred cross<br />

was adopted then as its symbol. Periodic<br />

international conferences systematically<br />

addressing clinical, research, <strong>and</strong> sociological<br />

aspects <strong>of</strong> TB were held until the outbreak <strong>of</strong><br />

the First World War in 1914.<br />

Establishment <strong>of</strong> the Union, 1920-1939<br />

In 1920, a conference on TB was convened in<br />

Paris in which 31 countries participated,<br />

including Australia, Bolivia, Brazil, Chile,<br />

China, Colombia, Cuba, Guatemala, Japan,<br />

Panama, Paraguay, Iran, <strong>and</strong> Thail<strong>and</strong>, in<br />

addition to those <strong>of</strong> Europe <strong>and</strong> North<br />

America. In an impressive procession,<br />

delegates one by one pledged “to agree on the<br />

means to fight TB, to make a consensus on the<br />

strategy, to jointly apply the most effective<br />

weapons to combat this common enemy,”<br />

thus establishing the International Union<br />

Against <strong>Tuberculosis</strong> (IUAT) in its present<br />

form. It was conceived as a federation <strong>of</strong><br />

national associations (130 by 1999). Ten<br />

international conferences followed until 1939.<br />

In order to supplement the routine reports <strong>of</strong><br />

the conferences, a regular publication was<br />

commenced in 1923. In this prewar period, the<br />

Bulletin included administrative reports <strong>and</strong><br />

statistics (subsequently compiled by WHO) as<br />

well as information on the strategy <strong>and</strong><br />

policies for the fight against TB <strong>and</strong> results <strong>of</strong><br />

numerous surveys on specific aspects <strong>of</strong> the<br />

disease <strong>and</strong> the campaign. The Bulletin<br />

TB <strong>Control</strong> at the Millennium<br />

34<br />

continued publication until mid-1940, the final<br />

editions containing the main reports to have<br />

been given at the 11 th conference planned for<br />

Berlin in September 1939, the very month<br />

when the Second World War commenced.<br />

Relaunching <strong>of</strong> the Union, 1946-1961<br />

At the first reunion <strong>of</strong> the Executive<br />

Committee after the war in 1946, the IUAT<br />

recommended to the planners <strong>of</strong> the future<br />

World <strong>Health</strong> Organization “establishment <strong>of</strong><br />

a strong Division <strong>of</strong> <strong>Tuberculosis</strong>.” Official<br />

relations with the WHO were then established<br />

which continue to the present time.<br />

The first postwar conference in 1950 in<br />

Copenhagen, with participation <strong>of</strong> 43 nations,<br />

was followed by a series <strong>of</strong> conferences, with<br />

the 29 th world conference in Bangkok in 1998,<br />

when 105 countries participated. Conferences<br />

outside North America <strong>and</strong> Europe were held<br />

in Brazil in 1952, India in 1957, <strong>and</strong> Turkey in<br />

1959. During this period a series <strong>of</strong><br />

international symposia were also organized,<br />

generally in Paris, addressing a variety <strong>of</strong><br />

topical issues such as TB in Africa, strain<br />

variation in BCG, radiography for TB, new<br />

drugs, <strong>and</strong> the role <strong>of</strong> voluntary agencies,<br />

among others.<br />

In order to strengthen the administration <strong>of</strong><br />

the growing agency, a post <strong>of</strong> full-time<br />

Executive Director was established in 1952. A<br />

system <strong>of</strong> quotas was devised for membership<br />

contributions. Over many years, the<br />

American Association has continually<br />

maintained a high quota share. Fees were also<br />

levied from individual members. In 1951,<br />

scientific committees were commenced <strong>and</strong><br />

met annually for intensive discussion <strong>of</strong> the<br />

emerging strategy for the fight against TB. In<br />

1953, regions were established in order to<br />

remain close to where the needs are. In 1958,<br />

the first international collaborative clinical<br />

trial for treatment <strong>of</strong> any disease was<br />

undertaken, with a total <strong>of</strong> 17,391 patients<br />

from 17 countries evaluated for drug<br />

resistance. This was followed by a

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