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CDC History of Tuberculosis Control - Medical and Public Health ...

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Lung Dis, 1998). Only 5%-10% <strong>of</strong> admissions<br />

to our nursing homes are TST positive now.<br />

Perhaps the principal discovery that has come<br />

from these data is that there is a significant<br />

difference in innate resistance to TB infection<br />

between whites <strong>and</strong> blacks. In addition, study<br />

<strong>of</strong> our TB case data base from 1976-1997<br />

shows that blacks with active TB are 50%<br />

more likely than whites to be sputum-smear<br />

positive <strong>and</strong> thus highly infectious.<br />

I am now preparing a paper to show the<br />

important public health implications <strong>of</strong> such a<br />

difference in TB risk. While health departments<br />

routinely try to identify all close contacts<br />

with infectious cases <strong>of</strong> TB, a particularly<br />

great effort should be made among the African<br />

American <strong>and</strong> Native American contacts<br />

because <strong>of</strong> their greater risk both <strong>of</strong> infection<br />

<strong>and</strong> <strong>of</strong> becoming infectious. It is important<br />

for such reactors to take the full course <strong>of</strong><br />

chemoprophylaxis to prevent development <strong>of</strong><br />

TB <strong>and</strong> further spread. This applies especially<br />

to exposures in close living quarters, i.e.,<br />

dormitories, nursing homes, shelters, <strong>and</strong><br />

prisons.<br />

It has been an interesting half century. The<br />

best part was the quarter century in public<br />

health in Arkansas from 1973-1998.<br />

Notable Events in TB <strong>Control</strong><br />

9<br />

TB <strong>Control</strong> in New York City:<br />

A Recent <strong>History</strong><br />

by Paula I. Fujiwara, MD, <strong>and</strong><br />

Thomas R. Frieden, MD, MPH<br />

Current <strong>and</strong> former Directors <strong>of</strong> the<br />

NYC TB <strong>Control</strong> Program<br />

Many <strong>of</strong> the tenets <strong>of</strong> modern TB control<br />

were developed more than a century ago in<br />

New York City by Dr. Hermann Biggs, a<br />

physician working for the Department <strong>of</strong><br />

<strong>Health</strong>. These included the policies <strong>of</strong> free,<br />

high-quality sputum examination, the m<strong>and</strong>atory<br />

reporting <strong>of</strong> cases, health department<br />

supervision <strong>of</strong> isolation <strong>and</strong> treatment, education<br />

<strong>of</strong> the public regarding TB, <strong>and</strong> the<br />

fostering <strong>of</strong> a social movement for control <strong>of</strong><br />

the disease. The City’s TB control program<br />

waxed <strong>and</strong> waned over the next 100 years,<br />

with the lowest number <strong>of</strong> reported TB cases<br />

in the city occurring in 1978.<br />

During the 1980s, the rapid rise in TB was<br />

fueled by the human immunodeficiency virus<br />

(HIV) epidemic; growing poverty,<br />

homelessness, <strong>and</strong> incarceration rates; <strong>and</strong><br />

immigration from countries with high TB<br />

prevalence. In this context, the infrastructure<br />

<strong>of</strong> TB control had been dismantled, the victim<br />

<strong>of</strong> a one-two knockout punch <strong>of</strong> a fiscal crisis<br />

in the City <strong>and</strong> a change to a system <strong>of</strong> block<br />

grants for federal funding. One long-time<br />

employee, when asked how it felt to see the<br />

increase in cases year after year, said, “We<br />

thought that’s just the way it was.” Staff were<br />

trapped in a cycle <strong>of</strong> reporting cases, starting<br />

treatment on those they could locate, but<br />

losing many <strong>of</strong> them. Staff knew they should<br />

be searching for the lost patients but were<br />

distracted by the overwhelming number <strong>of</strong><br />

new infectious cases. Citywide, less than half<br />

<strong>of</strong> the patients completed treatment. Repeated<br />

warnings from experts <strong>and</strong> panels did not lead<br />

to increased concern or funding.

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