Warfarin vs. Asprin in Reduced Ejection Fraction

CLINICAL IMPLICATIONS
• Given no overall benefit of warfarin and
increased risk of bleeding, in spite of
suggestive benefit at 4 years and beyond,
there is no compelling evidence to use
warfarin or aspirin for all patients.
• Given effectiveness in preventing stroke,
and possible benefit of warfarin after 4
years, analyses being performed to identify
groups that will benefit from warfarin or
aspirin.