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Warfarin vs. Asprin in Reduced Ejection Fraction

Warfarin vs. Asprin in Reduced Ejection Fraction

Warfarin vs. Asprin in Reduced Ejection Fraction

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No. at Risk<br />

Primary Outcome<br />

Aspir<strong>in</strong> 4,033 patient years (320 endpo<strong>in</strong>ts; 7.93% per year)<br />

<strong>Warfar<strong>in</strong></strong> 4,045 patient years (302 endpo<strong>in</strong>ts; 7.47% per year)<br />

Overall HR = 0.93 (0.79-1.10) p=0.40<br />

Proportional Hazards<br />

assumption violated<br />

Primary Analysis: Tx by Time Interaction<br />

Aspir<strong>in</strong> 1163 1073 860 658 508 329 94<br />

<strong>Warfar<strong>in</strong></strong> 1142 1049 852 653 525 363 115<br />

aspir<strong>in</strong><br />

warfar<strong>in</strong>

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