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Changing MIC Breakpoints: Do Mechanisms Count

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CLSI Guidelines<br />

Staph spp. Table 2C p. 70,78 M100-S21<br />

• An induced -lactamase test should be performed<br />

on staphylococcal isolates with penicillin <strong>MIC</strong>s<br />

0.12 ug/ml or zone dia. 29 mm before reporting<br />

isolate as penicillin susceptible …. A positive -<br />

lactamase test predicts resistance to penicillin.<br />

5

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