Changing MIC Breakpoints: Do Mechanisms Count
Changing MIC Breakpoints: Do Mechanisms Count
Changing MIC Breakpoints: Do Mechanisms Count
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Efficacy of different beta-lactams against an<br />
ESBL-producing K. pneumoniae in rat IAA Model<br />
Table 1: <strong>MIC</strong>s of various agents for K. pneumoniae 5657<br />
Antimicrobial Agent <strong>MIC</strong> at inoculum of:<br />
10 5 CFU/ml 10 7 CFU/ml<br />
Cefoperazone 2 256<br />
Sulbactam 32<br />
Cefoperazone-sulbactam (2:1) 0.5 256<br />
Cefotaxime 1 256<br />
Cefpirome 1 >256<br />
Ceftazidime >256<br />
Imipenem 0.5 16<br />
Rice LB et al. Antimicrob Agents Chemother.<br />
1991 Jun;35(6):1243-4.<br />
16