Changing MIC Breakpoints: Do Mechanisms Count
Changing MIC Breakpoints: Do Mechanisms Count Changing MIC Breakpoints: Do Mechanisms Count
MICs in g/ml: SHV-3 producing Citrobacter freundii Inocul. CFU/ml Pitfalls of ESBL Testing Effects of Inoculum Cefotaxime Ceftazidime Aztreonam Cefepime 5 x 10 5 2 1 0.5 0.5 (CLSI breakpoint 8 g/ml) Thomson KS, Moland ES: Antimicrob Agents Chemother. 2001 Dec;45(12):3548-54 12
MICs in g/ml: SHV-3 producing Citrobacter freundii Inocul. CFU/ml Pitfalls of ESBL Testing Effects of Inoculum Cefotaxime Ceftazidime Aztreonam Cefepime 5 x 10 5 2 1 0.5 0.5 5 x 10 7 256 32 32 >1024 (CLSI breakpoint 8 g/ml) Thomson KS, Moland ES: Antimicrob Agents Chemother. 2001 Dec;45(12):3548-54 13
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- Page 9 and 10: Clinical Studies • No randomized
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- Page 15 and 16: Efficacy of different beta-lactams
- Page 17 and 18: Efficacy of different beta-lactams
- Page 19 and 20: Efficacy of different beta-lactams
- Page 21 and 22: CAP Survey D-C 2007 D-19 C. freundi
- Page 23 and 24: New CLSI Guidelines 2010 • Proble
- Page 25 and 26: MIC Reproducibility • In this imp
- Page 27 and 28: Enterobacteriaceae Revised Breakpoi
- Page 29 and 30: Cephaloporin Breakpoints Following
- Page 31: New CLSI Guidelines 2010 • Proble
- Page 34 and 35: Why labs should continue to perform
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- Page 40 and 41: Something to Think About • Antibi
- Page 42 and 43: Personalized Antibiotic Report •
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- Page 46: Are the New CLSI Breakpoints the Co
<strong>MIC</strong>s in g/ml: SHV-3 producing Citrobacter freundii<br />
Inocul.<br />
CFU/ml<br />
Pitfalls of ESBL Testing<br />
Effects of Inoculum<br />
Cefotaxime Ceftazidime Aztreonam Cefepime<br />
5 x 10 5 2 1 0.5 0.5<br />
(CLSI breakpoint 8 g/ml)<br />
Thomson KS, Moland ES: Antimicrob Agents<br />
Chemother. 2001 Dec;45(12):3548-54<br />
12
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