Sample A: Cover Page of Thesis, Project, or Dissertation Proposal
Sample A: Cover Page of Thesis, Project, or Dissertation Proposal
Sample A: Cover Page of Thesis, Project, or Dissertation Proposal
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discovery <strong>of</strong> MACF1, a microtubule-actin crosslinking fact<strong>or</strong> 1, may have associations with<br />
TACC through its anch<strong>or</strong>ing to the golgi apparatus and its molecular mobility [28]. There are 3<br />
TACC human genes, which appear to be imp<strong>or</strong>tant f<strong>or</strong> cellular division and <strong>or</strong>ganization [28, 29],<br />
with <strong>or</strong>thologues rep<strong>or</strong>ted in Mus. musculus, Drosophila melangaster, and Xenopus laevis.<br />
Proper localization <strong>of</strong> TACC during cytokinesis appears to be dependent upon phosph<strong>or</strong>ylation<br />
by aur<strong>or</strong>a kinases [29, 30] and may posses a critical function in cell cycle control [31]. GAS6,<br />
growth arrest 6, is a gamma-carboxyglutamic acid (Gla)-containing protein and contrary to its<br />
name is thought to be involved in the stimulation <strong>of</strong> cell proliferation. Additionally, 3 genes are<br />
metabolic enzymes involved in tryptophan <strong>or</strong> tyrosine metabolism, as presented in Figure 10 [26].<br />
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