Sample A: Cover Page of Thesis, Project, or Dissertation Proposal

Figure 4.4: Signal intensity boxplots for Osteopontin. Boxplots of the log expression distributions, based
on aggregation of BaFL values, for ProbeSet 34342_s_at (SPP1). The Bhattacharjee data are shown. The
y-axis is the log-transformed BaFL value (natural log) of the expression values of all samples in the class,
and the x-axis indicates the sample class (the number of samples is very small in all class but the
adnocarcinoma). This figure is very similar to results shown in the 2005 plasma protein level study of
osteopontin in various lung cancers [19].
The similarity to the plasma protein levels reported by Hu, et al. is not matched by similarity to
the survival rates, or significance with regard to stage progression, reported by Donati, et al.,
shown in Figure 7 [20]. The R maxstat package was used to generate the following survival
rate figures [16].
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