hexachlorobutadiene - Davidborowski.com

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HEXACHLOROBUTADIENE 116 8. REFERENCES *Ishmael J, Lock EA. 1986. Nephrotoxicity of hexachlorobutadiene and its glutathione-derived conjugates. In: Presented at the Fourth International Symposium of the Society of Toxicologic Pathologists, June 5-7, 1985. Washington, DC. Toxicol Patho1 14:258-262. *Ishmael J, Pratt I, Lock EA. 1982. Necrosis of the pars recta (S3 segment) of the rat kidney produced by hexachloro-1,3-butadiene. J Pathol 138:99-l 13. *Ishmael J, Pratt I, Lock EA. 1984. Hexachloro-1,3-butadiene-induced renal tubular necrosis in the mouse. J Pathol 142:195-203. *Jaffe DR, Hassall CD, Brendel K. 1983. In vivo and in vitro nephrotoxicity of the cysteine conjugate of hexachlorobutadiene. J Toxicol Environ Health 11:857-867. *Johnson LD, Young JC. 1983. Inhibition of anaerobic digestion by organic priority pollutants. J Water Pollut Control Fed 55: 1141-l 149. *Jones TW, Gerdes RG, Ormstad K, et al. 1985. The formation of both a mono- and bis-substituted glutathione conjugate of hexachlorobutadiene by isolated hepatocytes and following in vivo administration to the rat. Chem Biol Interactions 56:251-267. *Jones TW, Chen Q, Schaeffer V, et al. 1988. Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate β-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity. Ma1 Pharm 341621-627. *Jonker D, Jones MA, van Bladeren PJ, et al. 1993a. Acute (24 hr) toxicity of a combination of four nephrotoxicants in rats compared with the toxicity of the individual compounds. Food Chem Toxicol 3 1:45-52. *Jonker D, Woutersen RA, van Bladeren PJ, et al. 1993b. Subacute (4-wk) oral toxicity of a combination of four nephrotoxins in rats: comparison with the toxicity of the individual compounds. Food Chem Toxicol 3 1: 125-136.
HEXACHLOROBUTADIENE 117 8. REFERENCES *Junk GA, Ford CS. 1980. A review of organic emissions from selected combustion processes. Chemosphere 9: 187-230. Kaminksy R, Kaiser KL, Hites RA. 1983. Fates of organic compounds from Niagara Falls dumpsites in Lake Ontario. J Great Lakes Res 9:183-189. *Kastl PE, Hermann EA. 1983. Quantitative gas chromatographic determination of hexachloro-1,3- butadiene in whole rat blood at part per trillion levels. Journal of Chromatography 280:390-393. Keith LH, Garrison AW, Allen FR, et al. 1976. Identification of organic compounds in drinking water from thirteen U.S. cities. In: Identification & analysis of organic pollutants in water. Ann Arbor, MI: Ann Arbor Science Publishers, Inc., 329-373. Kennedy GL, Graepel GJ. 1991. Acute toxicity in the rat following either oral or inhalation exposure. Toxicol Lett 56:317-326. Khalturin GU, Chudin VA, Andriushkeeva NI. 1984. [Hexachlorobutadiene distribution in rats during chronic intragastric adminstration.] Gig Sanit Oct. 10:91. (Russian). King JW. 1989. Fundamentals and applications of supercritical fluid extraction in chromatographic science. J Chromatog Sci 27:355-364. Kluwe WM, McNish R, Smithson K, et al. 1981. Depletion by l,2-dibromoethane, 1,2-dibromo-3- chloropropane, tris(2,3-dibromopropyl)phosphate, and hexachloro-1,3-butadiene of reduced nonprotein sulfhydryl groups in target and non-target organs. Biochem Pharmacol 30:2265-2271. Knocke WR, Conley L, van Benschoten JE. 1992. Impact of dissolved organic carbon on the removal of iron during water treatment. Water Res 26:1515-1522. *Kociba RJ Gehring PJ, Humiston CG, et al. 1971. Toxicologic study of female rats administered hexachlorobutadiene or hexachlorobenzene for thirty days. The Dow Chemical Company, Midland, Michigan.
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TOXICOLOGICAL PROFILE FOR HEXACHLOR
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HEXACHLOROBUTADIENE iii UPDATE STAT
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HEXACHLOROBUTADIENE 2 1.1 WHAT IS H
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HEXACHLOROBUTADIENE 4 1. PUBLIC HEA
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HEXACHLOROBUTADIENE 6 1. PUBLIC HEA
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HEXACHLOROBUTADIENE 9 2.1 INTRODUCT
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HEXACHLOROBUTADIENE 11 2. HEALTH EF
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FIGURE 2-1 Levels of Significant Ex
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4 Rat (F) 10-18 wk Renal 5 6 TABLE
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Reproductive 15 Rat 16 Rat 17 Mouse
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FIGURE 2-2 Levels of Significant Ex
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E psure to Hexachlorobutadiene - ra
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Species ACUTE EXPOSURE Death System
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HEXACHLOROBUTADIENE 35 2.2.3.8 Canc
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HEXACHLOROBUTADIENE 37 2.3.2 Distri
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HEXACHLOROBUTADIENE 63 2.9 ADEQUACY
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