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1482 S.H. Madsen et al. / Steroids 76 (2011) 1474–1482<br />

[23] Mak W, Shao X, Dunstan CR, Seibel MJ, Zhou H. Biphasic glucocorticoiddependent<br />

regulation <strong>of</strong> Wnt expression and its inhibitors in mature<br />

osteoblastic cells. Calcif Tissue Int 2009;85(6):538–45.<br />

[24] Buttgereit F, Zhou H, Kalak R, Gaber T, Spies CM, Huscher D, et al. Transgenic<br />

disruption <strong>of</strong> glucocorticoid signaling in mature osteoblasts and osteocytes<br />

attenuates K/BxN mouse serum-induced arthritis in vivo. Arthritis Rheum<br />

2009;60(7):1998–2007.<br />

[25] Zalavras C, Shah S, Birnbaum MJ, Frenkel B. Role <strong>of</strong> apoptosis in glucocorticoidinduced<br />

osteoporosis and osteonecrosis. Crit Rev Eukaryot Gene Expr<br />

2003;13(2–4):221–35.<br />

[26] Kerachian MA, Seguin C, Harvey EJ. Glucocorticoids in osteonecrosis <strong>of</strong> the<br />

femoral head: a new understanding <strong>of</strong> the mechanisms <strong>of</strong> action. J Steroid<br />

Biochem Mol Biol 2009;114(3–5):121–8.<br />

[27] Karsdal MA, Leeming DJ, Dam EB, Henriksen K, Alexandersen P, Pastoureau P,<br />

et al. Should <strong>subchondral</strong> <strong>bone</strong> turnover be targeted when treating<br />

osteoarthritis? Osteoarthritis Cartilage 2008;16(6):638–46.<br />

[28] Kwan TS, Lajeunesse D, Pelletier JP, Martel-Pelletier J. Targeting <strong>subchondral</strong><br />

<strong>bone</strong> for treating osteoarthritis: what is the evidence? Best Pract Res Clin<br />

Rheumatol 2010;24(1):51–70.<br />

[29] Madsen SH, Goettrup AS, Thomsen G, Christensen ST, Schultz N, Henriksen K,<br />

et al. Characterization <strong>of</strong> an ex vivo femoral head model assessed by markers<br />

<strong>of</strong> <strong>bone</strong> and cartilage turnover. Cartilage 2011;2(3):265–78.<br />

[30] Karsdal MA, Madsen SH, Christiansen C, Henriksen K, Fosang AJ, Sondergaard<br />

BC. Cartilage degradation is fully reversible in the presence <strong>of</strong> aggrecanase but<br />

not matrix metalloproteinase activity. Arthritis Res Ther 2008;10(3):R63.<br />

[31] Sorensen MG, Henriksen K, Schaller S, Henriksen DB, Nielsen FC, Dziegiel MH,<br />

et al. Characterization <strong>of</strong> osteoclasts derived from CD14 + monocytes isolated<br />

from peripheral blood. J Bone Miner Metab 2007;25(1):36–45.<br />

[32] Ghosh-Choudhury N, Windle JJ, Koop BA, Harris MA, Guerrero DL, Wozney JM,<br />

et al. Immortalized murine osteoblasts derived from BMP 2-T-antigen<br />

expressing transgenic mice. Endocrinology 1996;137(1):331–9.<br />

[33] Olsen AK, Sondergaard BC, Byrjalsen I, Tanko LB, Christiansen C, Muller A, et al.<br />

Anabolic and catabolic function <strong>of</strong> chondrocyte ex vivo is reflected by the<br />

metabolic processing <strong>of</strong> type II collagen. Osteoarthritis Cartilage<br />

2007;15(3):335–42.<br />

[34] Karsdal MA, Neutzsky-Wulff AV, Dziegiel MH, Christiansen C, Henriksen K.<br />

Osteoclasts secrete non-<strong>bone</strong> derived signals that induce <strong>bone</strong> formation.<br />

Biochem Biophys Res Commun 2008;366(2):483–8.<br />

[35] Jonsson KB, Frost A, Larsson R, Ljunghall S, Ljunggren O. A new fluorometric<br />

assay for determination <strong>of</strong> osteoblastic proliferation: effects <strong>of</strong> glucocorticoids<br />

and insulin-like growth factor-I. Calcif Tissue Int 1997;60(1):30–6.<br />

[36] Bay-Jensen AC, Liu Q, Byrjalsen I, Li Y, Wang J, Pedersen C, et al. Enzyme-linked<br />

immunosorbent assay (ELISAs) for metalloproteinase derived type II collagen<br />

neoepitope, CIIM-increased serum CIIM in subjects with severe radiographic<br />

osteoarthritis. Clin Biochem 2011;44(5-6):423–9.<br />

[37] Sumer EU, Sondergaard BC, Rousseau JC, Delmas PD, Fosang AJ, Karsdal MA,<br />

et al. MMP and non-MMP-mediated release <strong>of</strong> aggrecan and its fragments<br />

from articular cartilage: a comparative study <strong>of</strong> three different aggrecan and<br />

glycosaminoglycan assays. Osteoarthritis Cartilage 2007;15(2):212–21.<br />

[38] Henriksen K, Gram J, Neutzsky-Wulff AV, Jensen VK, Dziegiel MH, Bollerslev J,<br />

et al. Characterization <strong>of</strong> acid flux in osteoclasts from patients harboring a<br />

G215R mutation in ClC-7. Biochem Biophys Res Commun 2009;378(4):804–9.<br />

76<br />

[39] Camplejohn KL, Allard SA. Limitations <strong>of</strong> safranin ‘O’ staining in proteoglycandepleted<br />

cartilage demonstrated with monoclonal antibodies. Histochemistry<br />

1988;89(2):185–8.<br />

[40] Habib GS. Systemic effects <strong>of</strong> intra-articular corticosteroids. Clin Rheumatol<br />

2009;28(7):749–56.<br />

[41] Skwara A, Peterlein CD, Tibesku CO, Rosenbaum D, Fuchs-Winkelmann S.<br />

Changes <strong>of</strong> gait patterns and muscle activity after intraarticular treatment <strong>of</strong><br />

patients with osteoarthritis <strong>of</strong> the knee: a prospective, randomised,<br />

doubleblind study. Knee 2009;16(6):466–72.<br />

[42] Mansell JP, Collins C, Bailey AJ. Bone, not cartilage, should be the major focus in<br />

osteoarthritis. Nat Clin Pract Rheumatol 2007;3(6):306–7.<br />

[43] van der Kraan PM, Vitters EL, Postma NS, Verbunt J, Van den Berg WB.<br />

Maintenance <strong>of</strong> the synthesis <strong>of</strong> large proteoglycans in anatomically intact<br />

murine articular cartilage by steroids and insulin-like growth factor I. Ann<br />

Rheum Dis 1993;52(10):734–41.<br />

[44] Madsen SH, Sumer EU, Bay-Jensen AC, Sondergaard BC, Qvist P, Karsdal MA.<br />

Aggrecanase- and matrix metalloproteinase-mediated aggrecan degradation is<br />

associated with different molecular characteristics <strong>of</strong> aggrecan and separated<br />

in time ex vivo. Biomarkers 2010;15(3):266–76.<br />

[45] Augustine AJ, Oleksyszyn J. Glucocorticosteroids inhibit degradation in bovine<br />

cartilage explants stimulated with concomitant plasminogen and interleukin-<br />

1 alpha. Inflamm Res 1997;46(2):60–4.<br />

[46] Rauch A, Seitz S, Baschant U, Schilling AF, Illing A, Stride B, et al.<br />

Glucocorticoids suppress <strong>bone</strong> formation by attenuating osteoblast<br />

differentiation via the monomeric glucocorticoid receptor. Cell Metab<br />

2010;11(6):517–31.<br />

[47] Kalak R, Zhou H, Street J, Day RE, Modzelewski JR, Spies CM, et al. Endogenous<br />

glucocorticoid signalling in osteoblasts is necessary to maintain normal <strong>bone</strong><br />

structure in mice. Bone 2009;45(1):61–7.<br />

[48] Weinstein RS, Jilka RL, Almeida M, Roberson PK, Manolagas SC. Intermittent<br />

parathyroid hormone administration counteracts the adverse effects <strong>of</strong><br />

glucocorticoids on osteoblast and osteocyte viability, <strong>bone</strong> formation, and<br />

strength in mice. Endocrinology 2010;151(6):2641–9.<br />

[49] Henriksen K, Neutzsky-Wulff AV, Bonewald LF, Karsdal MA. Local<br />

communication on and within <strong>bone</strong> controls <strong>bone</strong> remodeling. Bone<br />

2009;44(6):1026–33.<br />

[50] Jevon M, Hirayama T, Brown MA, Wass JA, Sabokbar A, Ostelere S, et al.<br />

Osteoclast formation from circulating precursors in osteoporosis. Scand J<br />

Rheumatol 2003;32(2):95–100.<br />

[51] Takuma A, Kaneda T, Sato T, Ninomiya S, Kumegawa M, Hakeda Y.<br />

Dexamethasone enhances osteoclast formation synergistically with<br />

transforming growth factor-beta by stimulating the priming <strong>of</strong> osteoclast<br />

progenitors for differentiation into osteoclasts. J Biol Chem<br />

2003;278(45):44667–74.<br />

[52] Soe K, Delaisse JM. Glucocorticoids maintain human osteoclasts in the active<br />

mode <strong>of</strong> their resorption cycle. J Bone Miner Res 2010 [Epub ahead <strong>of</strong> print].<br />

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