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autoantibody assays 83 autobody
Actin Alanyl–tRNA synthetase AMA on HEp-2 AMA on kidney–stomach
Brush border 600× C-ANCA on formalin
fixed cells
Epstein–Barr virus), for which the nonspecific response
includes clones of cells specific for autoantigens; and
(3) by inducing the expression of antigens normally
repressed in host cells.
autoantibody assays
Tests for autoantibodies that can bind to self antigens
include a broad spectrum of techniques such as agglutination
(e.g., latex agglutination), indirect immunofluorescence,
indirect immunoperoxidase, radioimmunoassay, ELISA,
hemagglutination, bioassay, binding assay, and immobilization,
among others.
C-ANCA Centromere
Chromatin RW H38 DNA pos Crithidia DNA RW B16 Endomysial 400×
Endomysial 400× Fibrillarin Gastric parietal cell Gastric parietal cell-1
kidney-stomach
GBM Islet cell – primate pancreas
500×
Jo-1 Keratin antibody
Ku Lamin B LKM on liver and kidney Mitochondrial 500×
Examples of immunofluorescent stains of autoantibodies associated with various autoimmune diseases.
autoantigens
Normal body constituents recognized by autoantibodies
specific for them. T cell receptors may also identify
autoantigens (self antigens) when the immune reactivity has
induced a cell-mediated T lymphocyte response.
autobody
An antibody that exhibits the internal image of an antigen
as well as a binding site for an antigen. It manifests dual
binding to both idiotope and epitope. It bears an idiotope
that is complementary to its own antigen-binding site or
paratope. Thus, it has self-binding potential. This type of
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