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Appendix I 773 Mouse CD Chart Antigen Clones offered by BD Biosciences Alternate names of antigen CD135 A2F10.1 Flk-2, Flt3, Ly-72 CD137 1AH2 (aka 53A2) 4-1BB, Ly-63 CD138 281-2 Syndecan-1 CD140a APA5 PDGF Receptor α chain, PDGFR-a CD140b 28 PDGF Receptor β chain, PDGFR-b CD141 Thrombomodulin CD142 Tissue Factor, Coagulation Factor III CD143 Angiotensin coverting enzyme, dipeptidyl peptidase CD144 11D4.1 VE-Cadherin CD146 CD147 Basigin, HT7, neurothelin, gp42 CD148 PTPβ2, ByP CD150 IPO-3 CD151 SFA-1, PETA-3 Gene Flt3 Tnfrsf 9 Sdc1 Pdgfra Pdgfrb Thbd F3 Ace Cdh5 Mcam Bsg Ptprj Slam Cd151 Component of Molecular Weight Family/Superfamily 135-150 kDa Ig, RTK 30 kDa (monomer); 55 kDa (dimer); or 110 kDa (tetramer) TNFR 31 kDa core protein Glycosaminoglycan PDGF receptor homodimer and heterodimer 180 kDa CKR, RTK PDGF receptor homodimer and heterodimer 180 kDa CKR, RTK C-type lectin Serine protease cofactor Peptidylpeptidase 125 kDa Cadherin Ig Ig FNIII, PTP Ig TM4 Ligands/ Substrates flt3 Ligand 4-1BBL; fibronectin; laminin; vitronectin; collagen IV Interstitial matrix proteins PDGF A Chain; PDGF B Chain PDGF B Chain Thrombin Plasma factor VII/VIIa Angiotensin I Cd 144 Antigen Distribution Functions of Antigens Differentiation/ development; receptor/coreceptor Antigen presentation; signal transduction; activation/costimulation; adhesion Adhesion Signal transduction; differentiation/ development; receptor/coreceptor Signal transduction; differentiation/ development; receptor/coreceptor; chemotaxis Hemostasis Differentiation/ development?; hemostasis; angiogenesis Enzymatic activity Adhesion; angiogenesis Adhesion Adhesion Signal transduction Signal transduction Hemostasis? A I
I Appendix I 774 Mouse CD Chart Antigen Clones offered by BD Biosciences Alternate names of antigen CD152 9H10, UC10-4F10-11 CTLA-4, Ly-56 CD153 RM153 CD30 Ligand CD154 MR1 gp39, CD40 Ligand, Ly-62 CD156a MS2, ADAM 8 CD156q TACE, ADAM17 CD157 Ly-65, Bp-3, BST-1 CD159a 20d5 NKG2A, NKG2B CD160 BY55 CD161a NKR-P1A CD161b PK136 NKR-P1B CD161c PK136 NKR-P1C, NK-1.1, Ly-55 CD162 2PH1 P-selectin-IgG fusion protein P-selectin glycoprotein Ligand (PSGL-1) CD163 CD164 MGC-24, A115, A24 CD166 ALCAM, DM-GRASP Gene Cd152 Tnfsf 8 Tnfsf 5 Adam8 Adam17 Bst1 Klrc1 Cd160 Ly55a Ly55b Ly55c Selpl Cd163 Cd164 Alcam Component of Molecular Weight Family/Superfamily 33-37 kDa Ig 40 kDa TNF 39 kDa TNF 89 kDa Metalloproteinase 130 kDa Metalloproteinase 38-48 kDa ADP-ribosylcyclase Cd94/NKG2 heterodimers 38 kDa C-type lectin Ig 81 kDa C-type lectin 76-80 kDa C-type lectin 160 kDa Sialomucin SRCR 120 kDa Ig Ligands/ Substrates CD80; CD86 CD30 CD40 TNF-α; APP; CD62L Qa-1/Qdm CD62P CD6 Antigen Distribution Functions of Antigens Immunoregulation Activation/costimulation; immunoregulation Activation/costimulation Adhesion; enzymatic activity Adhesion; enzymatic activity; receptor/coreceptor Adhesion? Antigen recognition; signal transduction Activation/costimulation Adhesion Adhesion Activation/costimulation; adhesion; differentiation/development?
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ILLUSTRATED DICTIONARY OF IMMUNOLOG
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CRC Press Taylor & Francis Group 60
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Preface The splendid reception of t
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Illustration Credits Figure for C1
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Figure for Sustiva ® (efavirenz ca
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α helix 2 αβ TCR checkpoint muco
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abzyme 4 accessory molecules Trypan
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acetaldehyde adduct autoantibodies
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acquired immunity 8 activated lymph
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acute cellular rejection 10 acute d
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acute graft-vs.-host reaction 12 ac
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acute lymphoblastic leukemia (ALL)
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acute poststreptococcal glomerulone
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acyclic adenosine monophosphate (cA
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adhesion receptors 20 adjuvant ICAM
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adoptive immunization 22 adoptive t
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afferent lymphatic vessels 24 agar
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agretope 26 AIDS belt exposure to c
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airway hyper-responsiveness 28 alka
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allergic contact dermatitis 30 allo
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allophonic mouse 32 allotype suppre
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alternative complement pathway 34 a
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ALVAC 36 aminoethylcarbazole (AEC)
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amphiregulin 38 amyloid P component
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anaphylactoid reaction 40 anaphylax
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aneuploidy 42 angioimmunoblastic ly
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ankylosing spondylitis 44 antibodie
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antibody-dependent cell-mediated cy
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antibody unit 48 anti-CD5 monoclona
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anti-Clq antibody 50 anti-double-st
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antigen-binding site 52 antigen pre
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antigen-presenting cell (APC) 54 an
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antigenic gain 56 antigenic peptide
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antiglial fibrillary acidic protein
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anti-human cytokeratin 7 antibody 6
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anti-human prostatic acid phosphata
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antimuscle actin primary antibody 6
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antinucleosome antibodies 66 antipa
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antiprogesterone receptor antibody
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antithymocyte globulin (ATG) 70 AP-
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apoptosis 72 apoptosis Four caspase
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apoptosis, caspase pathway 74 apopt
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apoptosis, positive induction 76 ar
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Arthus reaction 78 artificially acq
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aspirin sensitivity reaction 80 ath
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Auer rods 82 autoantibodies, virus
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autochthonous 84 autogenous vaccine
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autoimmune complement fixation reac
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autoimmune uveoretinitis 88 avian i
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avidity hypothesis 90 AZT Percent A
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B7.2 costimulatory molecule 92 B ce
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B cell coreceptor 94 B cell lymphop
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B lymphocyte antigen receptor (BCR)
Page 113 and 114:
ackcross 98 bacterial immunity Euka
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actericidin 100 BALB/c mice bacteri
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asophil 102 Bcl-2 family A peripher
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enign 104 bentonite (Al 2O 3·4SiO
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β 1H 106 bifunctional antibodies
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iotin-avidin system 108 bispecific
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lood group antigens 110 BLR-1/MDR-1
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ooster phenomenon 112 botulinum tox
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equinar sodium (BQR) 114 Bretscher-
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Brucella vaccine 116 bullous pemphi
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ursa of Fabricius 118 butterfly ras
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c allotype A rabbit immunoglobulin
Page 138 and 139:
C1q deficiency 123 C2 and B genes C
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C3 nephritic factor (C3NeF) 125 C3d
Page 142 and 143:
C4d 127 C6 deficiency Immunofluores
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C9 deficiency 129 calcineurin above
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Calmette, Albert (1863-1933) 131 Ca
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caprinized vaccine 133 carbohydrate
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cardiolipin 135 cartilaginous fish
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Castleman’s disease 137 catalytic
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CD1a 139 CD3 α C1 COOH β m shown
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CD4 molecule 141 CD8 CD4 molecule E
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CD15 (Leu M1) 143 CD20 primary anti
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CD23(1B12) 145 CD32 stronger staini
Page 162 and 163:
CD42c 147 CD45RO 170 kDa. CD42b has
Page 164 and 165:
CD56 149 CD71 CD56 A 220/135-kDa mo
Page 166 and 167:
CD93 151 CDw116 CD93 A 120-kDa anti
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CDw149 (redesignated CD47R) 153 CD1
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CD236R 155 CD278 CD236R A 32-kDa an
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CD314 157 CD350 CD314 A 42-kDa anti
Page 174 and 175:
cell-bound antibody (cell-fixed ant
Page 176 and 177:
cellular hypersensitivity 161 c-erb
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chemokine β receptor-like 1 163 ch
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chemotactic peptide 165 Chido (Ch)
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cholera vaccine 167 chromogranin mo
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chronic and cyclic neutropenia 169
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chronic lymphocytic leukemia 171 ch
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circulating anticoagulant 173 Clado
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class I region 175 class II MHC mol
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classical C3 convertase 177 classic
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clonal selection theory 179 Clostri
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cobra venom factor (CVF) 181 coelom
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collagen (type I, II, and III) auto
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combination vaccine 185 common lymp
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complement activation 187 complemen
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complement membrane attack complex
Page 206 and 207:
concanavalin A (con A) 191 congenic
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consensus sequence 193 contact sens
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control tolerance 195 Coons, Albert
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corneal transplantation 197 cortico
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cowpox 199 C-reactive protein (CRP)
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cromolyn 201 cross tolerance cromol
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cryptodeterminant 203 cutaneous ana
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cyclooxygenase pathway 205 cyclospo
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CYNAP phenomenon 207 cytokeratin (3
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cytokine assays 209 cytokine-specif
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cytopathic effect (of viruses) 211
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cytotoxicity tests 213 cytotropic a
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Dameshek, William (1900-1969) 216 d
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decomplementation 218 degranulation
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delayed xenograft rejection 220 den
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density gradient centrifugation 222
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designer lymphocytes 224 desotope T
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dhobi itch 226 diathelic immunizati
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differentiation antigen 228 Dimsdal
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diphtheria toxoid 230 direct tag as
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diversity 232 DNA laddering Formati
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Doherty, Peter (1940-) 234 dot DAT
Page 251 and 252:
doubling dilution 236 drug-induced
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dye exclusion test 238 dysgammaglob
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EAE 240 Echinococcus immunity and c
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Edelman, Gerald Maurice (1929-) 242
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EIA 244 Elek plate e a e I d b a c
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ENA autoantibodies 246 endocytosis
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endoplasmic reticulum autoantibodie
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enzyme immunoassay (EIA) 250 eosino
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eotaxin-1 and eotaxin-2 252 epithel
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equilibrium constant 254 erythema n
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etanercept (injection) 256 exon for
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experimental autoimmune sialoadenit
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F-actin Actin molecules in a dual-s
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factor H deficiency 263 Faenia rect
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Farr technique 265 Fasciola immunit
Page 282 and 283:
FcμR 267 Fc receptors on human T c
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Fcγ R 269 feline immunity Fc R The
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Feulgen reaction 271 fibrin villous
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filariasis 273 fish immunity filari
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flame cells 275 FLIP/FLAM 95 40 78
Page 292 and 293:
Flt3 ligand 277 fluorescein isothio
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fluorescence treponemal antibody te
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follicular lymphoma 281 foscarnet i
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freemartin 283 functional affinity
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fusin 285 fyn fusin A receptor pres
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γδ T cells 288 gastric cell cAMP-
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gene amplification 290 gene escape
Page 307 and 308:
genetic polymorphism 292 genotype D
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Ghon complex 294 globulin Richard K
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glucocorticoids (GCs) 296 Gm alloty
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Golgi apparatus 298 Goodpasture’s
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gp41 300 graft changed the understa
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graft-vs.-leukemia (GVL) 302 granul
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granulomatous hepatitis 304 Guillai
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H-2 complex Murine major histocompa
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HALV (human AIDS-lymphotrophic viru
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Hassall’s corpuscles 311 HAT medi
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HCC-1 313 heavy chain diseases In t
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helminth 315 hematopoiesis thereby
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hemolysis 317 hemolytic plaque assa
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hepatitis A, inactivated and hepati
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hepatitis serology 321 herpes gesta
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herpesvirus-8 immunity 323 heteroph
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high endothelial postcapillary venu
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histamine-releasing factor 327 hist
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histoplasmin 329 HIV-1 genes G-O HL
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HIV infection 331 HLA Nuclear magne
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HLA allelic variation 333 HLA class
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HLA-DP subregion 335 HLA-DR antigen
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HLA type 337 homing Wells for diffe
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homologous recombination pathway 33
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HSC mobilization 341 (quadrivalent,
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HUT 78 343 hybrid resistance Baseme
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hyperacute xenograft rejection 345
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hypersensitivity angiitis 347 hypog
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I-309 A chemokine of the β (CC) fa
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idiotype suppression 351 Igα and I
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IgM 353 IL4 have recurrent respirat
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immediate spin cross match 355 immu
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immune exclusion 357 immune-neuroen
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immune response (Ir) genes 359 immu
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immunoblast 361 immunocytoadherence
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immunodeficiency associated with he
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immunoenhancement 365 immunofluores
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immunoglobulin A (IgA) 367 immunogl
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immunoglobulin δ chain 369 immunog
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immunoglobulin G (IgG) 371 immunogl
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immunoglobulin M (IgM) 373 immunogl
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immunoglobulin monomer 375 immunogl
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immunoglobulin structure 377 immuno
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immunologic facilitation (facilitat
Page 396 and 397:
immunologist 381 immunophenotyping
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immunoprophylaxis 383 immunoregulat
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immunotactoid glomerulopathy 385 in
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indirect tag assays 387 infectious
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inflammatory myopathy 389 influenza
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influenza virus vaccine 391 innate
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instructive theory of antibody form
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interallelic conversion 395 intercr
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interferon γ-1b (injection) 397 in
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interleukin-1 receptor antagonist p
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interleukin-2 receptor α subunit (
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interleukin-5 (IL5; eosinophil diff
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interleukin-6 receptor 405 interleu
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interleukin-8 receptor, type A (IL8
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interleukin-11 receptor (IL11R) 409
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interleukin-15 (IL15) 411 interleuk
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interleukin-20 (IL20) 413 interleuk
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interleukin-33 (IL33) 415 intracell
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invariant (Ii) chain 417 invariant
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iridovirus immunity 419 islet cell
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isoelectric point (pI) 421 isotypes
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Disulfide bonds β pleated sheets C
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Jerne network theory 425 Jo-1 syndr
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jugular bodies 427 juvenile rheumat
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kallidin 430 Kawasaki’s disease E
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Kidd blood group system 432 kinetoc
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KLH 434 Koprowski, Hilary (1916-) p
Page 451 and 452:
Kupffer’s cell 436 Kveim reaction
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lamina propria 438 laminin receptor
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Landsteiner’s rule (historical) 4
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LATS (long-acting thyroid stimulato
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lectin-like receptors 444 lepra cel
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leukemia 446 leukemia viruses Leuke
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leukocyte culture 448 leukocytoclas
Page 465 and 466:
levamisole 450 Levine, Philip Phili
Page 467 and 468:
light chain deficiencies 452 light
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linked recognition 454 linked recog
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linked suppression 456 Listeria imm
Page 473 and 474:
liver-kidney microsome 1 (LKM-1) au
Page 475 and 476:
LPS-binding protein (LBP) 460 lupus
Page 477 and 478:
lymphatic system 462 lymph node cau
Page 479 and 480:
lymphocyte-activating factor (LAF)
Page 481 and 482:
lymphocyte homing 466 lymphocyte tr
Page 483 and 484:
lymphocytotoxin 468 lymphoid tissue
Page 485 and 486:
lysogeny 470 lytic granules lysogen
Page 487 and 488:
macrophage 472 macrophage INFγ Mac
Page 489 and 490:
macrophage colony-stimulating facto
Page 491 and 492:
macrophage migration test 476 Madse
Page 493 and 494:
major histocompatibility complex cl
Page 495 and 496:
MART-1 (M2-7C10), mouse 480 mast ce
Page 497 and 498:
maternal antibodies 482 matrix meta
Page 499 and 500:
M component 484 Medawar, Peter Bria
Page 501 and 502:
medulla 486 membrane attack complex
Page 503 and 504:
membrane cofactor of proteolysis (M
Page 505 and 506:
mesangial phagocytes 490 methotrexa
Page 507 and 508:
MHC class III proteins 492 MHC rest
Page 509 and 510:
microinjection 494 microorganisms M
Page 511 and 512:
MiHA 496 Miller-Fisher syndrome (MF
Page 513 and 514:
MIP-2 (macrophage inflammatory prot
Page 515 and 516:
mixed agglutination 500 mixed lymph
Page 517 and 518:
Mo1 502 molecular (DNA) typing (seq
Page 519 and 520:
monoclonal antibody HECA-452 504 mo
Page 521 and 522:
monoclonal immunoglobulin 506 monoc
Page 523 and 524:
monogamous multivalency 508 monomer
Page 525 and 526:
mononuclear phagocyte 510 Montagnie
Page 527 and 528:
μ heavy chain disease 512 mucosal
Page 529 and 530:
multiple autoimmune disorder (MAD)
Page 531 and 532:
muramyl dipeptide (MDP) 516 myasthe
Page 533 and 534:
Mycoplasma-AIDS link 518 myelin aut
Page 535 and 536:
myelogenous leukemia 520 myocardial
Page 538 and 539:
N addition Appending nucleotides by
Page 540 and 541:
natural killer gene complex (NKC) 5
Page 542 and 543:
N-formyl peptide receptor (FPR) 527
Page 544 and 545:
neural cell adhesion molecule L1 (N
Page 546 and 547:
neutrophil activating protein 1 (NA
Page 548 and 549:
Nijmegen breakage syndrome (NBS) 53
Page 550 and 551:
nonresponder 535 normal lymphocyte
Page 552 and 553:
nuclear matrix protein 537 nutritio
Page 554 and 555:
O125 (ovarian celomic) Nonmucinous
Page 556 and 557:
oncogene 541 one-turn recombination
Page 558 and 559:
oral tolerance 543 Orthoclone OKT®
Page 560 and 561:
Oudin, Jacques (1908-1986) 545 ovar
Page 562 and 563:
owl eye appearance 547 oxygen-depen
Page 564 and 565:
P Abbreviation for properdin. Also
Page 566 and 567:
palivizumab (injection) 551 PAP (pe
Page 568 and 569:
papain hydrolysis 553 paracrine fac
Page 570 and 571:
parasite immunity 555 parietal cell
Page 572 and 573:
passive agglutination test 557 pass
Page 574 and 575:
Pasteurella immunity 559 pathogen-a
Page 576 and 577:
PCP 561 pemphigus foliaceus PCP Abb
Page 578 and 579:
penicillin hypersensitivity 563 pep
Page 580 and 581:
Percoll® 565 peripheral lymphoid o
Page 582 and 583:
persistent generalized lymphadenopa
Page 584 and 585:
phagocyte disorders 569 phagocytosi
Page 586 and 587:
phagolysosome 571 phorbol ester(s)
Page 588 and 589:
phytoimmunity 573 pituitary autoant
Page 590 and 591:
plaque-forming cells 575 plasma cel
Page 592 and 593:
plasmid 577 platelet antigens plasm
Page 594 and 595:
PMN 579 POEMS syndrome PMN Abbrevia
Page 596 and 597:
polyagglutination 581 polyclonal ly
Page 598 and 599:
polymeric Ig 583 polymyositis (PM)
Page 600 and 601:
positive induction apoptosis 585 po
Page 602 and 603:
preactivation 587 pre-B cell recept
Page 604 and 605:
precipitation in gel media 589 prec
Page 606 and 607:
Pressman, David 591 primary biliary
Page 608 and 609:
primary tumor 593 private specifici
Page 610 and 611:
progressive transformation of germi
Page 612 and 613:
prostatic acid phosphatase (PAP) 59
Page 614 and 615:
protein S 599 protoplast protein S
Page 616 and 617:
pseudoallergy 601 psoriasis vulgari
Page 618 and 619:
purine nucleoside phosphorylase (PN
Page 620 and 621:
Q fever An acute disease caused by
Page 622 and 623:
R5 viruses CCR5-binding HIV strains
Page 624 and 625:
adioimmunodiffusion test 609 radiol
Page 626 and 627:
Raji cell assay for CIC 611 rapamyc
Page 628 and 629:
RB200 613 reactive oxygen species (
Page 630 and 631:
ecombinant vaccine 615 refractory c
Page 632 and 633:
elative risk (RR) 617 reptile immun
Page 634 and 635:
estitope 619 reticulin autoantibodi
Page 636 and 637:
etrovirus 621 reverse transcriptase
Page 638 and 639:
hesus blood group system 623 rhesus
Page 640 and 641:
heumatoid arthritis cell (RA cell)
Page 642 and 643:
Ricinus communis 627 RNA polymerase
Page 644 and 645:
Rood, J. J. van 629 Rose-Waaler tes
Page 646:
RPR (rapid plasma reagin) test 631
Page 649 and 650:
Sabin-Feldman dye test 634 SAMS loc
Page 651 and 652:
sarcoma 636 scavenger receptors Ope
Page 653 and 654:
schlepper 638 scratch test schleppe
Page 655 and 656:
secondary immune response 640 secre
Page 657 and 658:
secretory piece 642 selective IgA d
Page 659 and 660:
self antigen 644 senescent cell ant
Page 661 and 662:
sequential determinant 646 serology
Page 663 and 664:
serum sickness 648 severe combined
Page 665 and 666:
Sézary syndrome 650 Shwartzman (or
Page 667 and 668:
sia test (historical) 652 side chai
Page 669 and 670:
signal sequence 654 single cysteine
Page 671 and 672:
Sips distribution 656 Sjögren’s
Page 673 and 674:
skin-reactive factor (SRF) 658 slow
Page 675 and 676:
smooth muscle antibodies (SMAs) 660
Page 677 and 678:
soluble cytokine receptors 662 spec
Page 679 and 680:
spectrotype 664 splenic cords spect
Page 681 and 682:
spontaneous cancer 666 SS-A/Ro in t
Page 683 and 684:
steric hindrance 668 Streptococcus
Page 685 and 686:
Strongyloides immunity 670 superant
Page 687 and 688:
suppressor T cells (Ts cells) 672 S
Page 689 and 690:
SXY-CIITA regulatory system 674 syn
Page 691 and 692:
systemic lupus erythematosus (SLE)
Page 694 and 695:
T1DM Abbreviation for type 1 diabet
Page 696 and 697:
Tamm-Horsfall glycoprotein (uromodu
Page 698 and 699:
T cell antigen-specific suppressor
Page 700 and 701:
T cell receptor (TCR) 685 T cell re
Page 702 and 703:
T cell tolerance 687 telencephalin
Page 704 and 705:
terminal deoxynucleotidyl transfera
Page 706 and 707:
tetanus toxoid 691 Th cells tetanus
Page 708 and 709:
T h1 cells 693 Theiler’s virus my
Page 710 and 711:
three-signal model of lymphocyte ac
Page 712 and 713:
thymic humoral factors (THFs) 697 t
Page 714 and 715:
thymus 699 thymus Marrow stem cell
Page 716 and 717:
thymus cell differentiation 701 thy
Page 718 and 719:
thymus-independent (TI) antigen 703
Page 720 and 721:
tissue transglutaminase autoantibod
Page 722 and 723:
T lymphocyte antigen receptor (TCR)
Page 724 and 725:
tolerosome 709 tonsil Susumu Tonega
Page 726 and 727:
toxin-1 (TSST-1) 711 TRALI (transfu
Page 728 and 729:
TRANCE (RANK ligand) 713 transformi
Page 730 and 731:
transgenes 715 translation chills,
Page 732 and 733:
T reg cells 717 triple response of
Page 734 and 735:
tuberculin hypersensitivity 719 tum
Page 736 and 737:
tumor-infiltrating lymphocytes (TIL
Page 738 and 739: tumor necrosis factor (TNF) recepto
Page 740 and 741: type I cytokine receptors 725 type
Page 742 and 743: type II interferon 727 type III imm
Page 744: typhus vaccination 729 tyrosine kin
Page 747 and 748: ulcerative colitis (immunologic col
Page 749 and 750: US28 734 uveitis Rhus toxicodendron
Page 751 and 752: valence 736 varicella valence The n
Page 753 and 754: vascular permeability factors 738 V
Page 755 and 756: venom 740 V gene Ileum Lumen the fi
Page 757 and 758: Videx® 742 viral hemagglutination
Page 759 and 760: vitamin B and immunity 744 vitronec
Page 761 and 762: Vpr (HIV) 746 V T region of lysis o
Page 763 and 764: warm antibody 748 Wegener’s granu
Page 765 and 766: Whipple’s disease 750 Winn assay
Page 767 and 768: Wu-Kabat plot 752 W, X, Y boxes (MH
Page 769 and 770: xenotype 754 X-linked lymphoprolife
Page 772: Rosalyn Sussman Yalow. Yalow, Rosal
Page 775 and 776: zinc and immunity 760 zinc and immu
Page 778 and 779: Appendix I Expression On most cells
Page 780 and 781: Appendix I 765 Mouse CD Chart Antig
Page 794: Activation unit Appendix II Complem
Page 797 and 798: III Appendix III 782 Cytokines and
Page 800 and 801: Appendix IV Chemokines and Their Re
Page 802 and 803: Appendix V Human Leukocyte Differen
Page 804 and 805: Appendix V 789 Human Leukocyte Diff
Page 816: Appendix V 801 Human Leukocyte Diff
Page 819: Editorial Staff Jeanann Lovell Sugg
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