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Untitled - D Ank Unlimited

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Vpr (HIV) 746 V T region<br />

of lysis of red blood cells coated with anti-erythrocyte<br />

antibodies under standard conditions.<br />

Vpr (HIV)<br />

A protein of the human immunodeficiency virus that<br />

facilitates passage of HIV DNA to the nucleus. It promotes<br />

G2 arrest and activation of the intrinsic apoptotic<br />

pathway.<br />

VpreB<br />

Refer to pre-B cell receptor.<br />

VpreB and λ5<br />

Proteins produced at the early pro-B cell stage of B cell<br />

development required for regulation of μ chain expression on<br />

cell surfaces. VpreB and λ5 replace immunoglobulin light<br />

chains in pre-B cells and play an important role in B cell<br />

differentiation.<br />

Vpu (HIV)<br />

A protein of the human immunodeficiency virus that combines<br />

with recently synthesized CD4 in the cytoplasm of<br />

host cells and targets it for ubiquitin-mediated degradation<br />

by proteasomes. It leads to formation of ion channels in the<br />

membranes of host cells to permit virus release. It interferes<br />

with the synthesis of MHC class I and increases susceptibility<br />

to the Fas-mediated apoptotic pathway.<br />

V region<br />

Refer to variable region.<br />

V region subgroups<br />

Individual chain V region subdivisions based on significant<br />

homology in amino acid sequence.<br />

V T region<br />

T lymphocyte antigen receptor variable region.

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