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anti-human glucagon antibody 61 anti-human myeloperoxidase antibody
anti-human glucagon antibody
A rabbit antibody that labels A cells of the endocrine mammalian
pancreas.
anti-human hemoglobin
A rabbit antibody against hemoglobin A isolated from
erythrocytes of normal adults that reacts with hemoglobin
A and, due to a common α chain, also with hemoglobin A 2
and hemoglobin F.
κ light chain⎯tonsil.
anti-human κ light chain antibody
A rabbit antibody that reacts with free κ light chains as well
as κ chains in intact immunoglobulin molecules. It may be
used for typing of free and bound monoclonal light chains
by immunoelectrophoresis and immunofixation and for
immunohistochemistry.
anti-human Ki-1 antigen (CD30) antibody
A mouse monoclonal antibody that reacts with a 595-amino
acid transmembrane 121-kDa glycoprotein. It contains
six cysteine-rich motifs in the extracellular domain and
is homologous to members of the nerve growth factor
receptor superfamily. The CD30 gene was assigned to
the short arm of chromosome 1 at position 36. The CD30
antigen was initially designated Ki-1. The antibody detects
a formalin-resistant epitope on the 90-kDa precursor molecule.
This molecule is processed in the Golgi system into
the membrane-bound, phosphorylated, mature, 120-kDa
glycoprotein and into the soluble 85-kDa form of CD30,
which is released from the supernatant and appears in
serum at detectable levels in conditions such as infectious
mononucleosis or neoplastically amplified CD30-positive
blasts. The CD30 antigen is expressed by Hodgkin and
Reed–Sternberg cells in Hodgkin disease, by the tumor
cells of a majority of anaplastic large cell lymphomas and
by a varying proportion of activated T and B cells. It is also
expressed on embryonal carcinomas.
anti-human Ki-67 antibody
A mouse monoclonal antibody directed against the Ki-67
nuclear antigen that may be used to aid in the identification of
proliferating cells in normal and neoplastic cell populations. It
is intended for qualitative staining in sections of formalin-fixed,
paraffin-embedded tissue (some form of antigen enhancement
is required for paraffin-embedded samples), frozen tissue, and
cytologic preparations. Ki-67 antibody specifically binds to
nuclear antigen(s) associated with cell proliferation and present
throughout the active cell cycle (G 1, S, G 2, and M phases) but
absent in resting (G 0) cells. Unexpected antigen expression
or loss of expression may occur, especially in neoplasms.
Occasionally stromal elements surrounding heavily stained
tissues and or cells will show immunoreactivity. The clinical
interpretation of any staining or its absence must be complemented
by morphological studies and evaluation of proper
controls.
anti-human λ light chain
A rabbit antibody that reacts with free λ light chains as well
as the λ light chains in intact immunoglobulin molecules.
anti-human luteinizing hormone (LH)
A rabbit antibody that labels gonadotropic cells of the
pituitary. Positive staining for adenohypophyseal hormones
assists in classification of pituitary tumors. Luteinizing hormone
(LH) is an adenohypophyseal glycoprotein hormone
found in gonadotropic cells of the anterior pituitary glands
of most mammals. Gonadotropic cells average about 10% of
anterior pituitary cells.
Myeloperoxidase⎯bone marrow.
anti-human myeloperoxidase antibody
An antibody used to discriminate between lymphoid leukemias
and myeloid leukemias in formalin-fixed, paraffinembedded
tissues.
Prostatic acid phosphatase (PSAP)⎯prostate.
A