Untitled - D Ank Unlimited

V gene segment 741 Vibrio cholerae immunity
MHC
Class I
Self
Epitope
TCR
CD8
CD3
Veto cell
Antigen-presenting cell
C gene in germline DNA, in lymphocyte and plasma cell
DNA the V gene lies near the 5′ end of the C gene from
which it is separated by a single intron.
V gene segment
DNA segment encoding the first 95 to 100 amino acid
residues of immunoglobulin and T cell polypeptide chain
variable regions. The two coding regions in the segment are
separated by a 100- to 400-bp intron. The first 5′ coding
region is an exon that codes for a brief untranslated mRNA
region and the first 15 to 18 signal peptide residues. The
second 3′ coding region is part of an exon that codes for terminal
4 signal peptide residues and 95 to 100 variable region
residues. A J gene segment encodes the rest of the variable
region. A D gene segment is involved in encoding immunoglobulin
heavy chain and T cell receptor β and δ chains.
V H region
The variable region of immunoglobulin heavy chain; that
part of a variable region encoded for by the VH gene segment.
+H 3 N
TCR
Class I
anti-MHC Anti-CD3
T cell T cell T cell
+H 3 N
V L
L Chain
V H
H Chain
The three mechanisms of the veto effect.
C L
C H 2
C H 3
S S
H Chain
C H1
S S
S S
– OOC COO –
viability techniques
Methods employed to determine the viability of cells maintained
in vitro. Of the many dyes used for viability assays,
anionic Trypan blue is the most frequently employed. For
example, the viability of leukocytes suspended in balanced
salt solution is evaluated based on their ability to exclude
Trypan blue from cell interiors. Leukocytes are counted in a
hemacytometer and the percentage of viability is calculated
by dividing the number of unstained viable cells by the
number of all cells counted (stained and unstained).
Vi antigen
A virulence antigen linked to Salmonella microorganisms.
It is found in the capsule and interferes with serological
typing of the O antigen, a heat-stable lipopolysaccharide
of enterobacteriaceae.
Vibrio cholerae immunity
Vibrio cholerae induces disease by production of virulence
factors and toxins. Protective antigens have been identified
H Chain
S
S
H Chain
V H and V I regions of an antibody molecule.
L Chain
+
NH3 +
NH3 V