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TLR1–10 706 T lymphocyte (T cell)
Antigen-presenting
cell (MHC/Antigen)
or
Mitogens
Resting
T cell
T lymphocyte (T cell) in peripheral blood.
2–8
Hours
for their failure to function in antigen presentation to T
lymphocytes.
TLR1–10
Refer to Toll-like receptors.
T lymphocyte (T cell)
A thymus-derived lymphocyte that confers cell-mediated
immunity and cooperates with B lymphocytes, enabling
them to synthesize antibody specific for thymus-dependent
antigens, including switching from IgM to IgG and/or IgA
production. T lymphocytes exiting the thymus recirculate
in the blood and lymph and in peripheral lymphoid organs.
They migrate to the deep cortices of lymph nodes. Those
in the blood may attach to postcapillary venule endothelial
cells of lymph nodes and to the marginal sinus in the spleen.
After passing across the venules into the splenic white pulp
or lymph node cortex, they reside there for 12 to 24 hours,
Activated
T cell early
T lymphocyte (T cell) activation.
3–10
Days
Activated
T cell late
IL-2
IL-2R
T lymphocyte (T cell).
exit by the efferent lymphatics, proceed to the thoracic duct,
and then proceed to the left subclavian vein where they
enter the blood circulation. Mature T cells are classified on
the basis of their surface markers, such as CD4 and CD8.
CD4 + T lymphocytes recognize antigens in the context of
MHC class II histocompatibility molecules. CD8 + T lymphocytes
recognize antigen in the context of MHC class I
histocompatibility molecules. CD4 + T cells participate in the