Untitled - D Ank Unlimited

post-transfusion graft-vs.-host disease 586 Prausnitz–Küstner (PK) reaction (historical)
however, a cytoplasmic antigen termed endostreptosin
together with some cationic streptococcal antigens are
found in glomeruli. Subepithelial immune deposits appear
as “humps.” They are antigen–antibody complexes that
may also appear in the mesangium or occasionally in
a subendothelial or intramembranous position. These
immune deposits stain positively for IgG and complement
by immunofluorescence. Affected children develop fever,
nausea, oliguria, and hematuria within 2 weeks following
a streptococcal sore throat or skin infection. Erythrocyte
casts and mild proteinuria may be identified. Periorbital
edema and hypertension may be observed upon examination.
BUN (blood urea nitrogen) and ASO titer may also
be elevated. More than 95% of children with poststreptococcal
glomerulonephritis recover, although a few (