Untitled - D Ank Unlimited

angiopoietins/Tie2 43 animal reservoir
A scheme for vessel sprouting (A) and for maturation of the new vessel (B). Vessel structure is maintained by action of Ang-1 on Tie2. In (A), replacement
of Ang-1 by Ang-2 destabilizes vessel integrity, facilitating vessel sprouting in response to VEGF. In (B), the new endothelial tubule interacts with
surrounding mesenchymal cells, in part through Ang-1, which acts on endothelial cell Tie2 to promote association of the new tubule with periendothelial
cells. The mechanism of this communication must involve other signals and is postulated to involve growth factors released from endothelial cells in
response to activated Tie2.
Angioimmunoblastic lymphadenopathy.
with plasma cells in lymph nodes revealing architectural effacement.
Arborization of newly formed vessels and proliferating
vessels with hyperplasia of endothelial cells is observed. In the
interstitium, amorphous, eosinophilic, PAS-positive deposits,
possibly representing debris from cells, are found. Fever, night
sweats, hepatosplenomegaly, generalized lymphadenopathy,
weight loss, hemolytic anemia, polyclonal gammopathy, and
skin rashes may characterize the disease in middle-aged to
older subjects. Patients live approximately 15 months, with
some developing monoclonal gammopathy or immunoblastic
lymphomas. AILA must be differentiated from AIDS, Hodgkin
disease, immunoblastic lymphoma, histocytosis X, and a variety
of other conditions affecting the lymphoid tissues.
angiopoietins/Tie2
Two endothelial cell-specific tyrosine kinase receptors are
Tie1 and Tie2. The ligands for Tie2 are angiopoietin-1 and
angiopoietin-2 (Ang-1 and Ang-2). The ligands for Tie1
have not been identified.
angry macrophage
A term sometimes used to refer to activated macrophages.
animal reservoir
An intermediate animal host for a pathogenic microorganism
whose primary host is another species.
Ankylosing spondylitis
.
A