Untitled - D Ank Unlimited

O125 (ovarian celomic)
Nonmucinous ovarian tumor antigen demonstrable with
homologous antibody by immunoperoxidase staining.
Selected mesotheliomas express this antigen as well.
OA
Abbreviation for ovalbumin.
Oakley–Fulthorpe test.
Oakley–Fulthorpe test
Double-diffusion type of precipitation test performed by
incorporating antibody into agar placed in a tube followed
by a layer of plain agar. A solution of antigen is placed on
top of the plain agar, and precipitation occurs where antigen
and antibody meet in the plain agar layer.
O antigen
(1) A lipopolysaccharide–protein antigen of enteric
microorganisms used for their serological classification. O
antigens of the Proteus species serve as the basis for the
Weil–Felix reaction used to classify Rickettsia. O antigens
of Shigella permit their subdivision into 40 serotypes.
The exterior oligosaccharide repeating unit side chain is
responsible for specificity and is joined to lipid A to form
lipopolysaccharide and to lipid B. The O antigen is the most
variable part of the lipopolysaccharide molecule. (2) In the
ABO blood group system, O antigen is an oligosaccharide
precursor form of A and B antigens: a fucose-galactose-Nacetylglucosamine-glucose.
O blood group
One of the groups described by Landsteiner in the ABO
blood group system. Refer to ABO blood group system.
O phage antibody library
Cloned antibody variable region gene sequences that may
be expressed as Fab or svFv fusion proteins with bacteriophage
coat proteins. They can be exhibited on phage
surfaces. The phage particle contains the gene encoding a
monoclonal recombinant antibody and can be selected from
the library by binding of the phage to specific antigen.
occupational allergy
Allergy induced by the type of work in which an individual
is engaged.
O
Oct-2
A protein formed early in the development of B lymphocytes
that has a role in immunoglobulin heavy chain
transcription.
OKT monoclonal antibodies
Commercially available preparations used to enumerate
human T cells according to their surface antigens to determine
the immunophenotype. OKT designations have been
replaced by CD designations.
Anti-CD3 monoclonal antibody interaction with CD3 at the T cell surface.
Specifically reacts with the T3-Antigen recognition
structure of human T cells
Orthoclone
OKT®3
Antigen recognition
structure
T3 complex
T cell
Orthoclone OKT®3 blocks T cell effector function
involved in renal allograft rejection
OKT ® 3 bound to CD3 complex of a T cell.
OKT ® 3 (Orthoclone OKT ® 3)
A commercial mouse monoclonal antibody against the CD3
T cell surface marker. It may be used therapeutically to
diminish T cell reactivity in organ allotransplant recipients
experiencing rejection episodes. OKT3 may act in concert
with the complement system to induce T cell lysis or
it may act as an opsonin, rendering T cells susceptible to
phagocytosis.
539
O