Untitled - D Ank Unlimited

Mo1 502 molecular (DNA) typing (sequence-specific priming
Legend:
Alkali-labile
tetrasaccharides
( )
En a TS
En a FS
En a FR
Alkali-stable
oligosaccharide
Cryptantigens
M/N
(N vg )
t
c?
t
Mo1
An adhesive glycoprotein present on neutrophils and
monocytes. It is also called Leu-CAM, which is an iC3b
receptor and thus helps mediate monocyte functions that
are complement-dependent.
modulated dendritic cell
A dendritic cell (DC) that induces anergy rather than
activation of naïve T cells, and/or propagation of T reg
cells. Interaction of DCs with T suppressor cells in vitro
or culture in the presence of low GM-CSF, high IL10
or TGF-β, or the presence of aspirin, corticosteroids, or
cyclosporine A that interferes with NF-κβ signaling may
lead to modulation. Referred to also as a tolerized or
tolerogenic DC.
modulation
Refer to antigenic modulation.
mofetumomab
A mouse monoclonal antibody labeled with 99m Tc used as a
diagnostic aid to ascertain the extent of disease and stage of
patients with small cell lung cancers. It unites with 40-kD
antigen present on numerous tumor cell types and also on
selected normal cells.
moesin
During chemokine-induced lymphocyte polarization, the
moesin cytoskeletal protein is important for the redistribution
of adhesion molecules to the cellular uropod.
f p
(T/Tn)
Pr
c?
Membrane
MN SGP, PAS-1,
glycophorin A,
or a-glycoprotein
(T/Tn)
Pr
Enzyme cleavage site on
intact red cells
Enzyme cleavage site on
SGP extracts and
approximate site on
intact red cells
f
f
U?
‘N’
Pr
(T/Tn)
S/s
c
f
p
Ss SGP, PAS-3,
glycophorin B,
or o-glycoprotein
c = Chymotrypsin
f = Ficin
p = Papain
t = Trypsin
En a TS = Trypsin-sensitive enzyme
En a FS = Ficin-sensitive enzyme
En a FR = Ficin-resistant enzyme
Membrane glycoproteins and glycosphingolipids that carry blood group antigens.
Moesin.
molecular (DNA) typing (sequence-specific priming
or SSP)
A method that employs a primer with a single mismatch in
the 3′ end that cannot be employed efficiently to extend a
DNA strand because the enzyme Taq polymerase, during
the PCR reaction, and especially in the first PCR cycles
which are very critical, does not manifest 3′-5′ proofreading
endonuclease activity to remove the mismatched nucleotide.
If primer pairs are designed to have perfectly matched 3′
ends with only a single allele or a single group of alleles and
the PCR reaction is initiated under stringent conditions, a