Untitled - D Ank Unlimited

immunoglobulin staining 376 immunoglobulin staining
N
N
IgM Fv fragment.
V
V C
C
C
C
C
?
N
N
TCR
N N
β α
CC (γ) V V (δ)
C C
CDR
N
?
FcRII
N
H
C
CD3γ(δ,ε)
N
H
C C
C
C
CDR
N
in the membrane form of IgM apparently represents the
hydrophobic transmembrane part of the chain.
immunoglobulin staining
Demonstrable by immunoperoxidase staining of plasma
cell and B lymphocyte cytoplasm in frozen or paraffinembedded
sections. B-5 fixative is preferable to formalin for
CLASS I MHC CLASS II MHC
α
N N
N
β2m C C C C
p-IgR
N
V
V
V
V
V
H
H
H
H
C
NCAM
N
H
C C
Immunoglobulin superfamily.
Ig IgG IgM IgA IgE IgD
H-chain
class
γ
Subclass γ 1 γ 2 γ 3 γ 4 α 1 α 2
α β
C C C
CD8
N N
α V V β
H
H
?
?
C C
Thy-1
C N
PDGFR
N
C
µ
α
ε δ
Heavy chain designations of immunoglobulins that determine class and
their subdivisons that determine subclass.