26.07.2013 Views

Untitled - D Ank Unlimited

Untitled - D Ank Unlimited

Untitled - D Ank Unlimited

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

IL5 354 immediate reaction<br />

IL5<br />

Abbreviation for interleukin-5.<br />

IL6<br />

Abbreviation for interleukin-6.<br />

IL7<br />

Abbreviation for interleukin-7.<br />

IL7Rd<br />

cDNA that encodes the receptor for IL7, known as IL7Rα,<br />

has been cloned from both humans and mice.<br />

IL8<br />

Abbreviation for interleukin-8.<br />

IL8RA<br />

Abbreviation for interleukin-8 receptor, type A.<br />

IL8RB<br />

Abbreviation for interleukin-8 receptor, type B.<br />

IL9<br />

Abbreviation for interleukin-9.<br />

IL10<br />

Abbreviation for interleukin-10.<br />

IL11<br />

Abbreviation for interleukin-11.<br />

IL12<br />

Abbreviation for interleukin-12.<br />

IL13<br />

Abbreviation for interleukin-13.<br />

IL14<br />

Abbreviation for interleukin-14.<br />

IL15<br />

Abbreviation for interleukin-15.<br />

IL16<br />

Abbreviation for interleukin-16.<br />

IL17<br />

Abbreviation for interleukin-17.<br />

IL18<br />

Abbreviation for interleukin-18.<br />

IL19<br />

Abbreviation for interleukin-19.<br />

IL20<br />

Abbreviation for interleukin-20.<br />

IL21<br />

Abbreviation for interleukin-21.<br />

IL22<br />

Abbreviation for interleukin-22.<br />

IL23<br />

Abbreviation for interleukin-23.<br />

IL24<br />

Abbreviation for interleukin-24.<br />

IL25<br />

Abbreviation for interleukin-25.<br />

IL26<br />

Abbreviation for interleukin-26.<br />

IL27<br />

Abbreviation for interleukin-27.<br />

IL28<br />

Abbreviation for interleukin-28.<br />

IL29<br />

Abbreviation for interleukin-29.<br />

IL30<br />

Abbreviation for interleukin-30.<br />

IL31<br />

Abbreviation for interleukin-31.<br />

IL32<br />

Abbreviation for interleukin-32.<br />

IL33<br />

Abbreviation for interleukin-33.<br />

IL34<br />

Abbreviation for interleukin-34.<br />

imbritumomab tiuxetan<br />

An anti-CD20 murine monoclonal antibody labeled with<br />

isotopic yttrium ( 90 Y) or indium ( 111 In). Isotopic radiation<br />

provides the antitumor activity. It is used in the treatment of<br />

patients with relapsed or refractory low-grade, follicular, or<br />

B cell non-Hodgkin lymphoma.<br />

ImD 50<br />

The antigen (or vaccine) dose capable of successfully<br />

immunizing 50% of a particular animal test population.<br />

IMiDs<br />

Immunomodulatory derivatives of thalidomide designed<br />

to be even more effective than thalidomide in regulating<br />

cytokines and affecting T cell proliferation.<br />

immature B cells<br />

B lymphocytes in which heavy and light chain variableregion<br />

gene rearrangement has occurred with expression of<br />

surface IgM, but not surface IgD.<br />

immature B lymphocyte<br />

A B cell that has rearranged a heavy and light chain<br />

variable-region gene and expresses surface IgM, but not<br />

surface IgD. It arises from bone marrow precursors that fail<br />

to proliferate or differentiate following exposure to antigen.<br />

By contrast, it undergoes apoptosis and is functionally unresponsive.<br />

This mechanism plays a role in the negative selection<br />

of B cells specific for self antigens in the bone marrow.<br />

immature dendritic cells<br />

Cells that exit the various body tissues in which they are<br />

present only in response to an inflammatory mediator or an<br />

infection. They take up antigen but fail to express costimulatory<br />

molecules and are unable to act as professional<br />

antigen-presenting cells to naïve T cells.<br />

immediate hypersensitivity<br />

Antibody-mediated hypersensitivity. In humans, this homocytotrophic<br />

antibody is IgE and in certain other species<br />

IgG 1. The IgE antibodies are attached to mast cells through<br />

their Fc receptors. Once the Fab regions of the mast cellbound<br />

IgE molecules interact with specific antigen, vasoactive<br />

amines are released from the cytoplasmic granules<br />

as described under type I hypersensitivity reactions. The<br />

term immediate is used to indicate that this type of reaction<br />

occurs within seconds to minutes following contact of a<br />

cell-fixed IgE antibody with antigen. Skin tests and RAST<br />

are useful for detecting immediate hypersensitivity in<br />

humans, and passive cutaneous anaphylaxis reveals immediate<br />

hypersensitivity in selected other species. Examples<br />

of immediate hypersensitivity in humans include the classic<br />

anaphylactic reaction to penicillin administration, hay fever,<br />

and environmental allergens such as tree and grass pollens,<br />

bee stings, etc.<br />

immediate reaction<br />

The onset of hypersensitivity within seconds to minutes following<br />

exposure to antigen. It is attributable to preformed<br />

antibodies in the blood circulation, such as IgE antibodies<br />

in humans, which mediate anaphylaxis. Refer also to immediate<br />

hypersensitivity reactions.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!