Untitled - D Ank Unlimited

fusin 285 fyn
fusin
A receptor present on CD4 + T lymphocytes and selected
other human cells that is linked to a G protein and is
believed to be requisite for human immunodeficiency virus
(HIV) fusion with target cells.
Fusobacterium immunity
F. nucleatum adheres to lymphocytes through lectin-like
ligands to facilitate other activity or exert an immunosuppressive
effect on them. The latter enhances the pathogenicity
of the microorganism. Patients with periodontal disease,
peritonsillar cellulitis and abscesses, infectious mononucleosis,
and acute streptococcal, nonstreptococcal, and recurrent
tonsilitis manifest increased levels of antibodies against
protein antigens of F. nucleatum. Antibodies against these
outer membrane proteins may point to a pathogenic role
for this microorganism in these infections. Delayed-type
hypersensitivity to F. necrophorum has been induced in
mice, and leukotoxin-specific antibodies have been found
in cattle. Natural infection or vaccination with a toxoid does
not always protect against reinfection. This microorganism
is believed to be a weak immunogenic pathogen.
Fv fragment
An antibody fragment consisting of the N terminal variable
segments of both heavy (V H) and light (V L) chain domains
that are joined by noncovalent forces. The fragment has one
antigen-binding site.
L1
L2
H3
L3
Fv region.
Fv region
The N terminal variable segments of both the heavy and
light chains in each Fab region of an immunoglobulin molecule
with a four-chain unit structure.
fyn
Refer to lck, fyn, ZAP (phosphotyrosine kinases in T cells).
H1
H2
5 Å
F