Untitled - D Ank Unlimited

acute lymphoblastic leukemia (ALL) 13 acute lymphoblastic leukemia (ALL)
0 SS 1024
CD10 1000
0.1
CD5 PC5 1000
0.1
C
0.1
0.1
B
CD45 ECD
1000
inflammation. Bradykinin is produced by activation of the
kinin system. It induces arteriolar dilation and increased
venule permeability through contraction of endothelial cells
and extravascular smooth muscle. Activation of bradykinin
precursors involves activated factor XII (Hageman factor)
generated by its contact with injured tissues. During clotting,
fibrinopeptides produced during the conversion of
fibrinogen to fibrin increase vascular permeability and are
chemotactic for leukocytes. The fibrinolytic system participates
in inflammation through the kinin system. Products
produced during arachidonic acid metabolism also affect
inflammation. These include prostaglandins and leukotrienes
that can mediate essentially every aspect of acute
inflammation.
1
E
3 4
1
CD45 GT
CD19 Positive
CD10 Positive
CD45
Positive
2
CD20
10 3
10 2
10 1
10 0
1 HLA-DR Positive
CD13 Negative
2
HLA-DR
E1 E2
0.0% 1.8%
E3 E4
0.0% 98%
100 101 102 103 1000
CD19 CD34
0.1 1000 0.1
1000
CD2 RD1
CD3 PE-CY5
CD 13 1000
0.1
2
1
CD2 Negative CD3 Negative
CD8 PE 1000
0.1
G G
3
4
3
0.1
Precursor B cell acute lymphoblastic leukemia.
E
4
1000
CD20 Negative
CD34 Positive
2
4
acute lymphoblastic leukemia (ALL)
An undifferentiated and very aggressive type of lymphoid
neoplasm that results from uncontrolled growth of
a progenitor cell that is believed to give rise to both B and
T lymphoid cell lineages. It consists of a heterogeneous
group of lymphopoietic stem cell disorders in which
lymphoblasts accumulate in the bone marrow and suppress
normal hemopoietic cells. Of all ALL cases, 80% are of
the B cell type, whereas the remainder are T cell with rare
cases of null cell origin. Ten percent (10%) of leukemias
are ALL, and 60% of ALL cases occur in children.
Chromosomal abnormalities have been found in most
cases of ALL. B-ALL (L3) is characterized by one of three
chromosomal translocations. Most B-ALL cases involve
A